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MEDICAL INFORMATION
Treclin Key Facts
Treclin gel contains a combination of two active ingredients. Clindamycin, an antibiotic that attacks bacteria on the skin, and tretinoin, a retinoid that reduces skin cells ability to stick together. This allows dead skin cells to be shed instead of blocking hair follicles. This helps to treat blackheads, whiteheads, papules and redness.
Treclin gel is only available with a prescription. NowPatient offers Treclin gel as a treatment for acne only, following an online consultation with a healthcare professional.
Key facts of Treclin gel
- For the treatment of moderate acne
- Treclin gel takes a few weeks to build up an effect. It is normally prescribed for 10-12 weeks
- Treclin gel has some common side effects which include skin irritation and dry skin
- It can be dangerous if you take Treclin gel with certain medications. If you’re not sure if it is safe, discuss this with the prescribing clinician
- Treclin gel is for topical use only
- Treclin gel is not recommended for the treatment of mild acne vulgaris
- Do not use Treclin gel at the same time as other topical treatments
- Avoid cleansers, scrubbing solutions, abrasive soaps and cosmetics with strong drying effects
- Treclin gel may make your skin more sensitive to light, causing sunburn. Use sunscreen with SPF 30 if you are exposed to strong sunlight
- Resistance may occur with other antibiotics such as lincomycin or erythromycin
Who is Treclin gel not suitable for?
Treclin gel may not be suitable for some people. To make sure it’s safe for you, speak to the prescribing clinician before using Treclin gel if you:
- Have hypersensitivity to clindamycin, tretinoin, or lincomycin
- Have ulcerative colitis, or antibiotic-associated colitis
- Have a family history of skin cancer
- Have acute eczemas, rosacea or perioral dermatitis
How and where to get Treclin gel?
You can buy Treclin safely and securely from NowPatient. You can start a consultation today for free and if you qualify for treatment, you only pay for the cost of the medication. Delivery is made to your home or office from our registered pharmacy.
Our service is certified, safe and effective, and we only ever treat conditions. If you book a consultation with one of our prescribers for the treatment of moderate acne, you can discuss if Treclin gel is a suitable treatment option for you.
At the end of the consultation, the clinician will decide if a treatment plan is suitable for you. If it is, the clinician will issue you with a prescription which can then be ordered, paid for and delivered directly to your chosen address by NowPatient.
Dosage and strength for Treclin gel for acne
Treclin gel 1%/0.025% is available as a translucent yellow gel when used for acne. It is manufactured by Meda Pharmaceuticals and comes in 30g tubes.
Information about how to use Treclin gel for acne
Treclin gel should be applied once daily at bedtime. Before using the gel, wash your face with mild soap and warm water. Pat dry with a towel. Using a pea-sized amount on one fingertip, dot the gel onto the face and gently rub in over your entire face.
Use Treclin gel as directed by your healthcare provider. Also, make sure you read the patient information leaflet given to you.
What happens if you use too much Treclin gel?
You should talk to your doctor or reach out to one of our prescribing clinicians, if you have used too much Treclin gel and you experience any side effects.
What are the side effects of Treclin gel?
Side effects of Treclin gel are split into common and serious.
Common side effects include:
- Stinging or skin pain
- Skin irritation
- Burning sensation
- Redness of the skin
- Dry skin
- Itching
Serious side effects include:
- Prolonged diarrhoea or abdominal cramps may indicate antibiotic-associated colitis
If you experience any serious side effects, you should contact NHS 111.
If you experience a serious allergic reaction with the signs shown below you should contact emergency services on 999.
- Your lips, mouth, throat or tongue suddenly become swollen
- You’re breathing very fast or struggling to breathe (you may become very wheezy or feel like you’re choking or gasping for air)
- Your throat feels tight or you’re struggling to swallow
- Your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet)
- You suddenly become very confused, drowsy or dizzy
- Someone faints and cannot be woken up
Always report adverse effects to the MHRA yellow card reporting system. You can read more about this here How and where do I report side effects of my medication?
Information about using Treclin gel at the same time as other medications or herbal supplements
There is not enough evidence to suggest there are any drug interactions between herbal supplements and Treclin gel. In any event, you should let your prescribing clinician know if you are taking any herbal supplements.
Caution is advised if using keratolytic agents such as benzoyl peroxide, resorcinol or chemical abrasives.
Why might Treclin gel not work for acne?
If you stop using Treclin gel or are not consistent with your use, improvements may disappear over time.
Can Treclin gel used for acne be used long term?
You should not exceed 12 weeks of continuous treatment with Treclin gel without evaluation from a healthcare provider.
Is there a herbal Treclin gel?
No. Herbal Treclin gel does not exist. If you have been marketed such a formulation, it may be fake.
Can women use Treclin gel?
Women of childbearing potential can use Treclin gel for the treatment of moderate acne only if contraception is used during treatment and for 4 weeks after stopping treatment. It is also advised that Treclin gel is not used by women who are breastfeeding due to insufficient data.
Should I avoid any particular food or drink when taking Treclin gel?
You can eat and drink normally when using Treclin gel.
What lifestyle changes can I make to help me with acne?
Lifestyle changes you can make include:
- Not washing affected areas of skin more often than twice a day as this may irritate your skin and make spots worse
- Washing affected skin with a mild soap or cleanser and lukewarm water
- Never squeeze spots as this can cause permanent scars
- Not to use too much make-up or cosmetics and use water-based make-up and toiletries that are less likely to block skin pores
Alternatives to Treclin gel
Alternatives for the treatment of acne include benzoyl peroxide gels such as Acnecide, topical antibiotics such as Zineryt lotion, retinoids such as Differin, Epiduo, and Skinoren.
Sources
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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FAQs
Answers to Popular Questions About Treclin
What is Treclin gel?
Treclin is a prescription-only topical gel used to treat acne vulgaris, particularly facial acne with both comedonal (blackheads and whiteheads) and inflammatory (red, swollen spots) components. It contains two active ingredients: clindamycin 1% (an antibiotic) and tretinoin 0.025% (a topical retinoid). Treclin gel is applied once daily in the evening and is suitable for adults and adolescents aged 12 years and over. It combines antibacterial action with retinoid-based skin cell turnover to address multiple acne mechanisms.
How does Treclin gel work?
Treclin works through two complementary mechanisms. Clindamycin kills Cutibacterium acnes bacteria by inhibiting bacterial protein synthesis, reducing infection and inflammation in acne lesions. Tretinoin (vitamin A acid) normalises the shedding of skin cells inside pores, preventing the formation of comedones (blocked pores), and promotes the turnover of skin cells. The combination targets both the bacterial and the comedonal components of acne, providing more comprehensive treatment than either ingredient alone.
Is Treclin gel available on the NHS?
Yes, Treclin gel is available on NHS prescription from GPs and dermatologists. It can also be prescribed through online services such as NowPatient. Treclin is commonly used when single-agent topical treatments have been insufficient or when acne has both comedonal and inflammatory components. Your prescriber will determine whether Treclin is appropriate based on the type and severity of your acne.
How do I apply Treclin gel?
Apply a pea-sized amount of Treclin gel once daily in the evening to clean, dry skin. Gently spread a thin layer over the entire acne-prone area, not just individual spots. Avoid the eyes, nostrils, mouth, and any broken or sunburnt skin. Wash your hands after application. Start by using Treclin every other evening for the first 1–2 weeks if your skin is sensitive, then increase to nightly use as tolerated. Allow the gel to absorb fully before applying any moisturiser.
How long does it take for Treclin to work?
Treclin typically takes 4–8 weeks before you see noticeable improvement. An initial worsening of acne (sometimes called a ‘retinoid purge’) may occur in the first 2–4 weeks as tretinoin increases skin cell turnover and brings underlying spots to the surface. This is normal and temporary. Full results are usually seen after 12 weeks of consistent use. Do not stop treatment early due to initial worsening — persistence is key to success with retinoid-containing products.
How long should I use Treclin for?
Treclin is typically used for 12 weeks per course, primarily because it contains the antibiotic clindamycin and prolonged antibiotic use increases the risk of bacterial resistance. After 12 weeks, your prescriber should reassess your acne. If ongoing retinoid treatment is needed, you may be switched to a retinoid-only product (such as adapalene or tretinoin alone) for maintenance. Repeated courses of Treclin may be prescribed if acne recurs.
What are the common side effects of Treclin?
Common side effects include skin dryness, peeling, redness, and a stinging or burning sensation, particularly in the first few weeks of use. These are largely due to the tretinoin component and usually improve as the skin adapts. Sun sensitivity is increased — always use a broad-spectrum SPF 30+ sunscreen during the day. Less commonly, contact dermatitis or excessive irritation may occur. Using a gentle, non-comedogenic moisturiser can help manage dryness and irritation.
Can I use Treclin in the sun?
Tretinoin makes the skin more sensitive to UV radiation. While using Treclin, you should apply a broad-spectrum SPF 30+ sunscreen every morning, avoid prolonged sun exposure, and not use sunbeds. If you are going to be in the sun, wear a hat and protective clothing. If you experience sunburn, stop using Treclin until the skin has fully healed. Sun sensitivity continues for a period after stopping tretinoin, so continue sun protection measures.
Can I use Treclin with other skincare products?
Yes, but be cautious. Avoid using other potentially irritating products at the same time as Treclin, including other retinoids, benzoyl peroxide (unless advised by your prescriber), glycolic acid, salicylic acid, and products containing alcohol. Use a gentle, fragrance-free cleanser and a non-comedogenic moisturiser. Sunscreen is essential. You can layer moisturiser over Treclin once it has absorbed. If using other active skincare ingredients, apply them at a different time of day (e.g., morning) to minimise irritation.
Can I use Treclin during pregnancy?
No, Treclin must not be used during pregnancy or if you are planning to become pregnant. Tretinoin is a retinoid and retinoids are known teratogens — they can cause serious birth defects. You should use effective contraception while using Treclin. If you become pregnant while using Treclin, stop the gel immediately and inform your doctor. Treclin should also be avoided during breastfeeding as clindamycin and tretinoin may pass into breast milk.
How can I get a prescription for Treclin?
Treclin is available on NHS prescription or privately through your GP, a dermatologist, or an online service like NowPatient. A prescriber will assess your acne severity and type to determine if Treclin is suitable. NowPatient offers convenient online consultations with UK-qualified prescribers and home delivery of your medication.
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