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Get prescribed Aknemycin Plus for Acne by a UK clinician through a free video consultation*. No questionnaires, no hidden fees. You only pay for your medication if approved.


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MEDICAL INFORMATION
Aknemycin Plus Key Facts
Aknemycin Plus is a topical acne treatment normally used for the treatment of mild to moderate acne. It works by reducing the number of spots and pimples caused by acne and treats skin infections. The solution also works on comedones, papules and pustules.
Aknemycin Plus contains a combination of two active ingredients. Erythromycin, an antibiotic that attacks bacteria on the skin, and tretinoin, a retinoid that reduces skin cells ability to stick together. This allows dead skin cells to be shed instead of blocking hair follicles. This helps to treat blackheads, whiteheads, papules and redness.
Aknemycin Plus is only available with a prescription. NowPatient offers Aknemycin Plus as a treatment for acne only, following an online consultation with a healthcare professional.
Key facts of Aknemycin Plus
- For the treatment of mild to moderate acne
- Aknemycin Plus takes a few weeks to build up an effect. It is normally prescribed for 9 -12 weeks
- Aknemycin Plus has some common side effects which include skin irritation and dry skin
- It can be dangerous if you use Aknemycin Plus with certain medications. If you’re not sure if it is safe, discuss this with the prescribing clinician
- Aknemycin Plus is for topical use only
- Do not use Aknemycin Plus at the same time as other topical treatments
- Avoid cleansers, scrubbing solutions, abrasive soaps and cosmetics with strong drying effects
- Resistance may occur with other antibiotics such as lincomycin or clindamycin
Who is Aknemycin Plus not suitable for?
Aknemycin Plus may not be suitable for some people. To make sure it’s safe for you, speak to the prescribing clinician before using Aknemycin Plus if you:
- Have hypersensitivity to erythromycin, clindamycin, tretinoin, or lincomycin
- Have ulcerative colitis, or antibiotic-associated colitis
- Have a family history of skin cancer
- Have acute eczemas, rosacea or perioral dermatitis
How and where to get Aknemycin Plus?
You can buy Aknemycin Plus safely and securely from NowPatient. You can start a consultation today for free and if you qualify for treatment, you only pay for the cost of the medication. Delivery is made to your home or office from our registered pharmacy.
Our service is certified, safe and effective, and we only ever treat conditions. If you book a consultation with one of our prescribers for the treatment of moderate acne, you can discuss if Aknemycin Plus is a suitable treatment option for you.
At the end of the consultation, the clinician will decide if a treatment plan is suitable for you. If it is, the clinician will issue you with a prescription which can then be ordered, paid for and delivered directly to your chosen address by NowPatient.
Dosage and strength for Aknemycin Plus for acne
Aknemycin Plus 4%/0.025% is available as a solution when used for acne. It is manufactured by Almirall Ltd and comes in 25 mL bottles.
Information about how to use Aknemycin Plus for acne
Before using Aknemycin Plus solution, clean your face with a mild cleanser. Using the applicator, apply Aknemycin Plus thinly to the affected skin, once or twice a day as directed by your doctor. Do not use cosmetics or moisturisers until the solution has been absorbed into your skin. Also, avoid using sunbeds or sun lamps at any time while using Aknemycin Plus.
Use Aknemycin Plus as directed by your healthcare provider. Also, make sure you read the patient information leaflet given to you.
What happens if you use too much Aknemycin Plus?
You should talk to your doctor or reach out to one of our prescribing clinicians, if you have used too much Aknemycin Plus and you experience any side effects.
What are the side effects of Aknemycin Plus?
Side effects of Aknemycin Plus are split into common and serious.
Common side effects include:
- Stinging or skin pain
- Skin irritation
- Burning sensation
- Redness of the skin
- Dry skin
- Peeling, crusting
- A warm sensation on the applied area
- A temporary change in skin complexion
If you experience any serious side effects, you should contact NHS 111.
If you experience a serious allergic reaction with the signs shown below you should contact emergency services on 999.
- Your lips, mouth, throat or tongue suddenly become swollen
- You’re breathing very fast or struggling to breathe (you may become very wheezy or feel like you’re choking or gasping for air)
- Your throat feels tight or you’re struggling to swallow
- Your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet)
- You suddenly become very confused, drowsy or dizzy
- Someone faints and cannot be woken up
Always report adverse effects to the MHRA yellow card reporting system. You can read more about this here How and where do I report side effects of my medication?
Information about using Aknemycin Plus at the same time as other medications or herbal supplements
There is not enough evidence to suggest there are any drug interactions between herbal supplements and Aknemycin Plus. In any event, you should let your prescribing clinician know if you are taking any herbal supplements.
Caution is advised if using keratolytic agents such as benzoyl peroxide, resorcinol or chemical abrasives.
Why might Aknemycin Plus not work for acne?
If you stop using Aknemycin Plus or are not consistent with your use, improvements may disappear over time.
Can Aknemycin Plus used for acne be used long term?
You should not exceed 12 weeks of continuous treatment with Aknemycin Plus without evaluation from a healthcare provider.
Is there a herbal Aknemycin Plus?
No. Herbal Aknemycin Plus does not exist. If you have been marketed such a formulation, it may be fake.
Can women use Aknemycin Plus?
Aknemycin Plus can be used by women, but is not recommended for use by pregnant or women trying to get pregnant. Aknemycin Plus is also not recommended when breastfeeding as the active ingredients can pass into breast milk.
Should I avoid any particular food or drink when taking Aknemycin Plus?
You can eat and drink normally when using Aknemycin Plus.
What lifestyle changes can I make to help me with acne?
Lifestyle changes you can make include:
- Not washing affected areas of skin more often than twice a day as this may irritate your skin and make spots worse
- Washing affected skin with a mild soap or cleanser and lukewarm water
- Never squeeze spots as this can cause permanent scars
- Not use too much make-up or cosmetics and use water-based make-up and toiletries that are less likely to block skin pores
Alternatives to Aknemycin Plus
Alternatives for the treatment of acne include benzoyl peroxide gels such as Acnecide, topical antibiotics such as Zineryt lotion, retinoids such as Differin, Epiduo gel (adapalene and benzoyl peroxide), and Skinoren.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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FAQs
Answers to Popular Questions About Aknemycin Plus
What is Aknemycin Plus?
Aknemycin Plus is a prescription topical solution for acne vulgaris containing erythromycin 4% and tretinoin 0.025%. It combines a macrolide antibiotic with a topical retinoid, providing antibacterial and comedolytic (unblocking pores) activity in a single product. Aknemycin Plus is applied to acne-affected skin and is suitable for mild to moderate acne. The combination of antibiotic and retinoid also helps reduce the risk of antibiotic resistance compared to using erythromycin alone.
How does Aknemycin Plus work?
The erythromycin component kills Cutibacterium acnes bacteria by inhibiting protein synthesis, reducing the bacterial load that drives acne inflammation. The tretinoin component is a retinoid that normalises follicular keratinisation (the shedding of skin cells inside pores), preventing blocked pores (comedones) and promoting the turnover of existing lesions. Together, they address both the bacterial and comedonal aspects of acne.
How do I use Aknemycin Plus?
Apply Aknemycin Plus once or twice daily to clean, dry skin, as directed by your prescriber. Apply a thin layer to the entire acne-affected area, not just individual spots. Avoid the eye area, mouth, and any broken skin. Because it contains tretinoin, the skin may become more sensitive to sunlight — use SPF 30+ sunscreen daily and avoid excessive sun exposure. Some initial mild irritation and skin peeling is normal and usually settles within 2–4 weeks.
What are the side effects of Aknemycin Plus?
Common side effects include skin dryness, peeling, mild stinging or burning on application, redness, and photosensitivity (increased sun sensitivity). These effects are mainly due to the tretinoin component and usually improve over 2–4 weeks as the skin adapts. Use a gentle, fragrance-free moisturiser and SPF 30+ sunscreen. If severe irritation occurs, reduce to once-daily application or take a break from treatment and consult your prescriber.
Can I use Aknemycin Plus during pregnancy?
No, Aknemycin Plus must not be used during pregnancy or if planning pregnancy. The tretinoin component is a retinoid, and all retinoids are contraindicated in pregnancy due to the risk of birth defects. If you are of childbearing potential, reliable contraception should be used during treatment. Consult your prescriber for pregnancy-safe acne alternatives.
How can I get Aknemycin Plus?
Aknemycin Plus requires a prescription from your GP, dermatologist, or online prescriber such as NowPatient. It is available on the NHS. Your prescriber will assess your acne severity and determine the most appropriate treatment plan.
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