Elleste Solo
Book a quick face-to-face video consultation with a certified prescribing pharmacist, nurse, or doctor. If approved, your Elleste Solo will be prescribed* and delivered straight to your door with free next-day delivery†. No hidden fees. No delays. Just expert care.
* Includes Free Private Prescription & Consultation.
† Applies to UK only.


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MEDICAL INFORMATION
Elleste Solo Key Facts
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Evorel
About Elleste Solo
Elleste Solo tablets are a form of HRT (hormone replacement therapy), used to treat the symptoms of the menopause. Elleste Solo contains estradiol as the active ingredient, which is identical to the female hormone oestrogen and is suitable for women who have had a hysterectomy.
Declining hormone levels of oestrogen at menopause can cause:
- Osteoporosis
- Hot flushes
- Depression
- Sleep problems
- Vaginal dryness
If you have not had a hysterectomy, you will also be prescribed a progestogen alongside Elleste Solo or a combined HRT, such as Elleste Duet. If only oestrogen levels are increased, the endometrium will grow excessively, increasing your risk of endometrial cancer.
NowPatient offers Elleste Solo as a treatment for HRT only, following an online consultation with a prescribing clinician.
Key facts of Elleste Solo
- For the treatment of HRT
- Elleste Solo has some common side effects which include nausea and headaches
- Elleste Solo will not prevent pregnancy in otherwise fertile women
- Do not use a hormonal contraceptive when treated with a HRT
- It can be dangerous if you take Elleste Solo with certain medications. If you’re not sure if it is safe, discuss this with the prescribing clinician
Who is Elleste Solo not suitable for?
Elleste Solo may not be suitable for some people. To make sure it’s safe for you, speak to the prescribing clinician before taking Elleste Solo if you:
- Are allergic to the active ingredient, estradiol hemihydrate
- Have ever had breast cancer
- Have cancer sensitive to oestrogen
- Have untreated endometrial hyperplasia (an excessively thick womb lining)
- Suffer from a blood clots
- Suffer from porphyria
- Have had a heart attack, angina, stroke, or high blood pressure
- Have vaginal bleeding
- Have liver disease
- Are pregnant or breastfeeding
- Have fibroids
- Have uterine problems such as endometriosis or endometrial hyperplasia
- Have diabetes
- Suffer from migraines
- Have gallstones
- Have asthma
- Have epilepsy
- Have fluid retention
- Have high fat levels in the blood
- Are obese
- Have a hereditary ear disorder
How and where to get Elleste Solo?
You can buy Elleste Solo safely and securely from NowPatient. You can start a consultation today for free and if you qualify for treatment, you only pay for the cost of the medication. Delivery is made to your home or office from our registered pharmacy.
Our service is certified, safe and effective, and we only ever treat conditions. If you book a consultation with one of our prescribers for the treatment of HRT, you can discuss if Elleste Solo is a suitable treatment option for you.
At the end of the consultation, the clinician will decide if a treatment plan is suitable for you. If it is, the clinician will issue you with a prescription which can then be ordered, paid for and delivered directly to your chosen address by NowPatient.
Dosage and strength for Elleste Solo for HRT
Elleste Solo is available as 1mg and 2mg tablets tablets when used for HRT.
Information about how to take Elleste Solo for HRT
Elleste Solo tablets should be taken at the same time each day. Swallow the tablets whole with water, with or without food. If you forget to take a tablet, take it as soon as you can. If it is almost time for your next dose, skip the missed dose and take your next dose at the usual time. Read the patient information leaflet provided or speak to your healthcare provider for further information.
What happens if you take too much Elleste Solo?
If you take more than prescribed, then it can lead to some unpleasant side effects. You should talk to your doctor or reach out to one of our prescribing clinicians, if you have taken too much Elleste Solo and you experience any of the following side effects.
What are the side effects of Elleste Solo?
Possible side effects of Elleste Solo are split into common and serious.
Common side effects include:
- Nausea
- Headache
- Breast tenderness
- Breakthrough bleeding
- Change in sex drive
- Stomach cramps
- Fluid retention
Serious side effects include:
- Blood clots
- Stroke
- Heart disease – chest pain passing into the neck or arm
- Liver disease – jaundice (yellowing of the skin or eyes)
If you experience any serious side effects, you should contact NHS 111.
If you experience a serious allergic reaction with the signs shown below you should contact emergency services on 999.
- Your lips, mouth, throat or tongue suddenly become swollen
- You’re breathing very fast or struggling to breathe (you may become very wheezy or feel like you’re choking or gasping for air)
- Your throat feels tight or you’re struggling to swallow
- Your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet)
- You suddenly become very confused, drowsy or dizzy
- Someone faints and cannot be woken up
Always report adverse effects to the MHRA yellow card reporting system. You can read more about this here How and where do I report side effects of my medication? – NowPatient
Information about taking Elleste Solo at the same time as other medications or herbal supplements
There is not enough evidence to suggest there are any drug interactions between herbal supplements and Elleste Solo. In any event, you should let your prescribing clinician know if you are taking any herbal supplements or other prescription drugs, such as:
- Phenytoin or carbamazepine
- Rifampicin
- Ritonavir or nelfinavir
- Warfarin
- St John’s Wort
Can Elleste Solo taken for HRT be taken long term?
HRT should only be used as a short-term treatment for the menopause. Speak to your GP to review your treatment at least once each year and have regular checkups.
Is there a herbal Elleste Solo?
No. Herbal Elleste Solo does not exist. If you have been marketed such a formulation, it may be fake.
Can women use Elleste Solo?
Women can take Elleste Solo for HRT, but should speak to a doctor if considering taking while pregnant or breastfeeding.
Should I avoid any particular food or drink when taking Elleste Solo?
You can eat and drink normally when taking Elleste Solo.
What lifestyle changes can I make to help me with menopause?
You modify your lifestyle in a number of ways, and this may have a positive impact on your symptoms:
- Using a fan
- Cool showers
- Light clothing
- Lubricants
- Healthy diet
- Regular exercise
- Quit smoking
Alternatives to Elleste Solo
Alternative oestrogen-only HRT include Progynova and Zumenon.
Sources
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
Related Articles
FAQs
Answers to Popular Questions About Elleste Solo
What is Elleste Solo?
Elleste Solo is a hormone replacement therapy (HRT) product containing oestradiol (estradiol), a form of the natural female hormone oestrogen. It is available as tablets in 1 mg and 2 mg strengths. Elleste Solo provides oestrogen-only HRT and is used to relieve menopausal symptoms such as hot flushes, night sweats, vaginal dryness, and mood changes in women who have had a hysterectomy. Women with an intact uterus must take a progestogen alongside Elleste Solo to protect the womb lining.
How does Elleste Solo work?
Elleste Solo replaces the oestrogen that the ovaries stop producing during and after the menopause. The declining oestrogen levels are responsible for menopausal symptoms. By supplementing oestradiol, Elleste Solo alleviates vasomotor symptoms (hot flushes, night sweats), urogenital symptoms (vaginal dryness, discomfort), mood disturbances, and helps maintain bone density, reducing the risk of osteoporotic fractures.
Who is Elleste Solo suitable for?
Elleste Solo (oestrogen-only HRT) is primarily intended for women who have had a hysterectomy, as they do not need the womb-protective effect of a progestogen. It is used for moderate to severe menopausal symptoms that significantly affect quality of life. Women with an intact uterus should use a combined HRT product (oestrogen plus progestogen) such as Elleste Duet, or add a separate progestogen to Elleste Solo.
How do I take Elleste Solo?
Take one Elleste Solo tablet daily, at the same time each day. Swallow the tablet whole with water. It can be taken with or without food. Treatment is continuous — take one tablet every day without a break. Your prescriber will start you on the lowest effective dose (usually 1 mg) and adjust if needed based on symptom control. Always use the lowest dose that controls your symptoms.
How long can I take Elleste Solo for?
The duration of HRT should be reviewed at least annually with your prescriber. NICE guidance states that there is no arbitrary limit on the duration of HRT — the decision to continue should be based on an individual assessment of benefits and risks. Many women take HRT for 5 years or longer. For women taking HRT primarily for bone protection, the benefits continue for as long as treatment is taken.
What are the side effects of Elleste Solo?
Common side effects include breast tenderness, headaches, nausea, bloating, and leg cramps. These often settle within the first 3 months. Breakthrough bleeding may occur, particularly when starting treatment or changing dose. Less common side effects include mood changes, skin reactions, and fluid retention. If breast tenderness is persistent, a dose reduction may help.
Does Elleste Solo increase the risk of breast cancer?
Oestrogen-only HRT (such as Elleste Solo, used after hysterectomy) is associated with little or no increase in breast cancer risk when used for up to 5 years. Beyond 5 years, any increase in risk is small. The Women’s Health Initiative study found no significant increase in breast cancer with oestrogen-only HRT over 7 years. Your prescriber will discuss the individual risk-benefit balance with you.
Does Elleste Solo increase the risk of blood clots?
Oral HRT, including Elleste Solo tablets, is associated with a small increase in the risk of venous thromboembolism (VTE). The risk is approximately 1.7 times higher than in non-users, but the absolute risk remains low. Transdermal HRT (patches or gels) does not increase VTE risk and may be preferred for women with VTE risk factors. Discuss your individual risk with your prescriber.
Can I take Elleste Solo if I still have my womb?
If you have not had a hysterectomy, you must take a progestogen alongside Elleste Solo to protect the womb lining from thickening (endometrial hyperplasia), which can lead to womb cancer. Your prescriber may add a separate progestogen (such as Utrogestan or Provera) for at least 12 days each month, or may recommend switching to a combined HRT product like Elleste Duet.
How can I get Elleste Solo?
Elleste Solo is available on NHS prescription from your GP, menopause clinic, or through online services like NowPatient. Your prescriber will assess your menopausal symptoms, medical history, and risk factors to determine whether HRT is appropriate. NowPatient offers online consultations with qualified UK prescribers and home delivery.
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