EVOREL

Treatment options

Buy EVOREL safely, securely and easily in a few simple steps. Start a consultation today to check your eligibility with a prescribing clinician, at no cost to you.

Includes Free Private Prescription

This content is intended for UK audiences only

Navin Khosla NowPatientGreen tick
Updated on 26 Mar 2024
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What to do if you missed your EVOREL dose

The MHRA's reporting program for suspected side effects to medicines, vaccines, e-cigarettes, medical device incidents, defective or falsified (fake) products to the Medicines and Healthcare products Regulatory Agency to ensure safe and effective use.

Learn more about reporting side effects

Other known brand names

Estraderm, Estradot

About  Evorel

Evorel patches are classed as a hormone replacement therapy (HRT). It contains estradiol, which acts in the same way as the female sex hormone oestrogen and is used to treat the symptoms of menopause.

If only oestrogen levels are increased during HRT treatment, the endometrium would grow excessively, causing an increased risk of endometrial cancer. If you have not had a hysterectomy you will be prescribed a progestogen with Evorel.

Evorel helps to treat menopausal symptoms such as:

  • Osteoporosis
  • Hot flushes, night sweats
  • Depression, mood swings
  • Sleep problems
  • Vaginal dryness

NowPatient offers Evorel patches as a treatment for HRT only, following an online consultation with a prescribing clinician.

Key facts of Evorel

  • For the treatment of HRT
  • Evorel has some common side effects which include nausea and headaches
  • Evorel will not prevent pregnancy in otherwise fertile women
  • Do not use a hormonal contraceptive when treated with a HRT
  • It can be dangerous if you use Evorel with certain medications. If you’re not sure if it is safe, discuss this with the prescribing clinician
  • Evorel Conti patches (50mcg estradiol and 170mcg norethisterone acetate) are used in postmenopausal women who have not had a period in the last 18 months

Who is Evorel not suitable for?

Evorel may not be suitable for some people. To make sure it’s safe for you, speak to the prescribing clinician before using Evorel if you:

  • Have hypersensitivity to the active ingredients estradiol
  • Have ever had breast cancer
  • Have cancer sensitive to oestrogen
  • Have untreated endometrial hyperplasia (an excessively thick womb lining)
  • Suffer from a blood clots
  • Suffer from porphyria
  • Have had a heart attack, angina, stroke, or high blood pressure
  • Have unusual vaginal bleeding
  • Have liver disease or any other liver problems
  • Are pregnant or breastfeeding
  • Have fibroids
  • Have uterine problems such as endometriosis or endometrial hyperplasia
  • Have diabetes
  • Suffer from migraines
  • Have gallbladder disease
  • Have asthma
  • Have epilepsy
  • Have fluid retention
  • Have high cholesterol levels in the blood
  • Are obese
  • Have a hereditary ear disorder

How and where to get Evorel?

Evorel patches are available with a prescription only. It is not available over the counter at a pharmacy.

NowPatient does not allow customers to buy Evorel patches directly. Our service is certified, safe and effective, and we only ever treat conditions. If you book a consultation with a prescribing clinician for the treatment of HRT, you can discuss if Evorel is a suitable treatment option for you.

At the end of the consultation, the clinician will decide if a treatment plan is suitable for you. If it is, the clinician will issue you with a prescription which can then be ordered, paid for and delivered directly to your chosen address by NowPatient.

Dosage and strength for Evorel patches for HRT

Evorel patches contain estradiol as the active ingredient. It is available as:

  • Evorel 25 which gives 25mcg of estradiol in 24 hours
  • Evorel 50 which gives 50mcg of estradiol in 24 hours
  • Evorel 100 which gives 100mcg of estradiol in 24 hours

Information about how to use Evorel for HRT

The Evorel patch should be applied to a clean and dry area of skin. You may choose to apply the patch to your thighs or bottom. The patch must be changed twice a week, on the same two days each week. You should not apply the new patch to the same area of skin and do not apply the patch around your breasts. Read the patient information leaflet provided or speak to a healthcare professional for further information.

What happens if you use too much Evorel?

If you use more than prescribed, then it can lead to some unpleasant side effects. You should talk to your doctor or reach out to one of our prescribing clinicians, if you have used too much Evorel and you experience any of the following side effects:

What are the side effects of Evorel?

Side effects of Evorel are split into common and serious.

Common side effects include:

  • Nausea
  • Headache, dizziness
  • Breast tenderness, breast pain
  • Change in sex drive
  • Anxiety, insomnia
  • Stomach pain, indigestion, flatulence, diarrhoea
  • Irregular bleeding
  • Acne, skin irritation, rash
  • Vaginal discharge
  • Fluid retention, weight gain, bloating

Serious side effects include:

  • Blood clots
  • Stroke
  • Heart disease – chest pain passing into the neck or arm
  • Liver disease – jaundice (yellowing of the skin or eyes), abdominal pain

If you experience any serious side effects, you should contact NHS 111.

If you experience a serious allergic reaction with the signs shown below you should contact emergency services on 999.

  • Your lips, mouth, throat or tongue suddenly become swollen
  • You’re breathing very fast or struggling to breathe (you may become very wheezy or feel like you’re choking or gasping for air)
  • Your throat feels tight or you’re struggling to swallow
  • Your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet)
  • You suddenly become very confused, drowsy or dizzy
  • Someone faints and cannot be woken up

Always report adverse effects to the MHRA yellow card reporting system. You can read more about this here How and where do I report side effects of my medication? – NowPatient

Information about using Evorel at the same time as other medications or herbal supplements

There is not enough evidence to suggest there are any drug interactions between herbal supplements and Evorel. In any event, you should let your prescribing clinician know if you are taking any herbal supplements or other prescription drugs, such as:

  • Phenytoin or carbamazepine
  • Rifampicin
  • Ritonavir or nelfinavir
  • Warfarin
  • St John’s Wort

Can Evorel used for HRT be used long term?

HRT should only be used as a short-term treatment for the menopause. Women who use HRT for more than 5 years may be at an increased risk of ovarian cancer. Speak to your GP to review your treatment at least once each year and have regular checkups.

Is there a herbal Evorel?

No. Herbal Evorel does not exist. If you have been marketed such a formulation, it may be fake.

Should I avoid any particular food or drink when using Evorel?

You can eat and drink normally when using Evorel.

What lifestyle changes can I make to help me with HRT?

You modify your lifestyle in a number of ways, and this may have a positive impact on your symptoms:

  • Using a fan
  • Cool showers
  • Light clothing
  • Lubricants
  • Healthy diet
  • Regular exercise
  • Quit smoking

Alternatives to Evorel

Alternative HRT patches include Estaderm and Estradot patches.

Sources

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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