Estradot Conti

Other Related Names or Treatments

Evorel Conti

FemSeven Conti

About Estradot Conti

Estradot Conti is a continuous combined HRT containing estradiol (a form of oestrogen) and norethisterone acetate (a progestogen) as the active ingredients. Estradot Conti is used to treat post-menopausal women to relieve symptoms caused by low oestrogen levels.

Estradot Conti helps to reduce common menopausal symptoms such as hot flushes, night sweats, sleep disturbance, mood changes, and vaginal dryness. The progestogen component helps to protect the lining of the womb. This is needed when oestrogen is taken by women who still have a uterus.

Estradot Conti Patches are a prescription-only medication recommended to be used when menopausal symptoms have a significant impact on daily life or when other treatments are unsuitable or not well tolerated.

NowPatient offers Estradot Conti as a treatment for menopause following an online consultation with a clinician.

Key facts of Estradot Conti

• Used to treat menopausal symptoms such as hot flushes, night sweats, mood changes, and vaginal dryness
• Applied to dry, intact skin twice a week (every 3 to 4 days)
• Common side effects include headaches, breast tenderness, nausea, mild skin irritation, or spotting
• There is a very low risk of blood clots or stroke with the patch
• You should seek medical advice if you notice leg swelling, chest pain, or any sudden changes in bleeding
• Avoid applying the patches over cuts, folds, or irritated skin and replace the patch immediately if it falls off

Who is Estradot Conti suitable for?

Estradot Conti is suitable for post-menopausal women who have not had a period for at least 12 months and are experiencing menopausal symptoms such as hot flushes, night sweats, mood changes, or vaginal dryness.

Who is Estradot Conti not suitable for?

Estradot Conti may not be suitable for some people. To make sure it’s safe for you, speak to the NowPatient prescribing clinician before using Estradot Conti if you:

• Have a history of venous thromboembolism (blood clots)
• Have had a stroke, heart attack, or other arterial clot disease
• Have liver disease or abnormal liver function
• Have any undiagnosed vaginal bleeding
• Have a history of oestrogen-sensitive cancer, such as breast cancer or cancer of the womb lining

Do not use Estradot Conti patches if you have a condition that is strictly contraindicated for oestrogen-progestogen therapy.

How and where to get Estradot Conti

You can access Estradot Conti safely and securely through NowPatient. You can start a consultation today for free, and if you qualify for treatment, you only pay for the medication. Delivery is made to your home or office from our registered pharmacy.

Our service is certified, safe, and effective, and we only provide treatment for conditions that require clinical assessment. If you book a consultation with a prescribing clinician for the management of menopausal symptoms, you can discuss whether Estradot Conti is a suitable treatment option for you.

At the end of the consultation, the clinician will decide if a treatment plan is appropriate. If it is, the clinician will issue a prescription, which can then be ordered, paid for, and delivered directly to your chosen address by NowPatient.

Dosage and strength for Estradot Conti Patches

Estradot Conti patches are available in 30/95 mcg and 30/140 mcg strengths.

The patch should be applied to dry, intact skin twice a week (every 3 to 4 days). Your prescribing clinician will determine the lowest effective dose to relieve menopausal symptoms and may adjust the dose based on your response and needs.

What happens if you use too many Estradot Conti Patches?

Using more than the prescribed amount of the Estradot Conti patches will not improve menopausal symptoms faster and may increase the risk of side effects, such as breast tenderness, nausea, headache, or irregular bleeding.

If you accidentally apply more than the recommended dose, remove the extra patch and contact your prescribing clinician for advice. Seek urgent medical attention by ringing 999 or NHS 111 if you experience severe symptoms, such as swelling, chest pain, or sudden shortness of breath.

What are the side effects of Estradot Conti?

Common side effects:

• Headache
• Breast tenderness or pain
• Nausea
• Mood changes
• Irregular vaginal bleeding or spotting (usually in the first few months)
• Skin irritation or redness where the patch is applied

Serious side effects:

• Pain, swelling, or redness in one leg. Can be a sign of a blood clot (DVT)
• Chest pain or breathlessness. Could indicate a clot in the lungs or heart issue
• Sudden weakness, numbness, or slurred speech. Possible stroke
• Changes in vaginal bleeding after months of use. May signal a more serious condition
• Breast lumps or changes. Could be a sign of breast cancer, continue regular screening

Common side effects will improve over time and serious side effects are rare. If you do experience any serious side effects, contact NHS 111.

If you experience a serious allergic reaction with the following signs, call 999 immediately:

• Swelling of lips, tongue, throat, or face
• Difficulty breathing, wheezing, or tight throat
• Skin turning blue, grey, or very pale, or sudden dizziness/confusion
• Fainting or inability to wake someone up

Always report adverse effects to the MHRA Yellow Card reporting system. You can read more about this here: How and where do I report side effects of my medication?

Information about using Estradot Conti with other medications

Using Estradot Conti alongside certain other medicines may affect how it works or increase the risk of side effects. This includes:

• Drugs that induce drug‑metabolising enzymes such as phenobarbital, phenytoin, and carbamazepine. These may increase the metabolism of oestrogens and progestogens, potentially reducing their effects
• Certain anti-infective medicines such as rifampicin or rifabutin and some HIV medicines, such as nevirapine and efavirenz, which may also reduce hormone levels
• Some strong CYP3A4 inhibitors, such as ketoconazole or erythromycin which can increase exposure to estradiol
• Herbal preparations like St John’s wort may increase your metabolism, lowering hormone levels
• Caution is advised when taking estradiol with cyclosporine, as it may increase cyclosporine levels
• Certain lab tests such as thyroid function or glucose tolerance tests may be affected by oestrogen therapy

Always let your prescribing clinician know about all the medications, supplements, or herbal remedies you are taking before starting Estradot Conti, so they can make sure it is safe for you to take.

Why Estradot Conti Patches might not work as well for some people

• The hormones (estradiol and norethisterone) in the patches may be metabolised faster in some individuals due to enzyme induction, causing its effects to be reduced
• Hormone levels delivered may be lower than expected due to poor skin absorption if the patch is applied to irritated or compromised skin
• Some medicines such as certain anticonvulsants, or anti‑infective drugs can increase the breakdown of the hormones, leading to reduced effectiveness

Can Estradot Conti Patches be used long term?

Estradot Conti Patches can be used for long-term management of menopausal symptoms, but treatment should be at the lowest effective dose and reviewed regularly by a healthcare professional. Duration of therapy should be based on individual needs, balancing symptom relief with any potential risks, and ongoing assessment is recommended.

How to store Estradot Conti Patches

• Keep Estradot Conti Patches out of the sight and reach of children
• Do not use this medicine after the expiry date shown on the carton or blister (marked as “EXP”). The expiry date refers to the last day of that month
• Store the patch below 25°C in its original packaging to protect it from moisture and light
• Do not dispose of used or unused patches in wastewater or household waste. Speak to your pharmacist on how to safely dispose of the patches

Is there a herbal Estradot Conti?

No. There is no herbal version of Estradot Conti available. Any product marketed as a “herbal” Estradot Conti may be counterfeit or unsafe, and should not be used.

Should I avoid any particular food or drink when using Estradot Conti Patches?

You can eat and drink normally while using Estradot Conti Patches. There are no specific foods or drinks that need to be avoided, and a normal diet does not affect how the patches work.

What lifestyle changes can help with menopausal symptoms?

Certain lifestyle changes can help reduce menopausal symptoms alongside Estradot Conti Patches:

• Maintain a balanced diet and regular meals
• Engage in regular physical activity, including aerobic and strength exercises
• Practice stress management techniques, such as mindfulness or relaxation exercises
• Maintain a healthy weight, as this can help reduce hot flushes and night sweats
• Avoid triggers that worsen symptoms, such as excessive caffeine, alcohol, or spicy foods
• Maintain a cool sleeping environment and wear breathable clothing to reduce night sweats

Alternatives to Estradot Conti Patches

• Evorel Conti patches: A continuous HRT patch containing estradiol and norethisterone acetate
• FemSeven Conti patches: These patches contain estradiol with another type of progestogen (levonorgestrel)
• Estradiol-only patches or gels with separate progestogen such as, estradiol patches (Estradot mono) with added oral norethisterone or progestogen

Your prescribing clinician can help you decide the most appropriate alternative based on your individual clinical needs and risk profile.