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MEDICAL INFORMATION
Evorel Conti Key Facts
Other Related Names or Treatments
Estraderm, Estradot
About Evorel Conti
Evorel Conti patches are classed as a hormone replacement therapy (HRT). It contains estradiol and norethisterone, which act in the same way as the female sex hormones oestrogen and progesterone. Evorel Conti patches are used in postmenopausal women who have not had a period in the last 18 months.
If only oestrogen levels are increased during HRT treatment, the endometrium would grow excessively, causing an increased risk of endometrial cancer. This is why you will be prescribed Evorel Conti patches (which contains a progestogen) if you have not had a hysterectomy.
Evorel Conti helps to treat menopausal symptoms such as:
- Osteoporosis
- Hot flushes, night sweats
- Depression, mood swings
- Sleep problems
- Vaginal dryness
NowPatient offers Evorel Conti patches as a treatment for HRT only, following an online consultation with a prescribing clinician.
Key facts of Evorel Conti
- For the treatment of HRT
- Evorel Conti has some common side effects which include nausea and headaches
- Evorel Conti will not prevent pregnancy in otherwise fertile women
- Do not use a hormonal contraceptive when treated with a HRT
- It can be dangerous if you use Evorel Conti with certain medications. If you’re not sure if it is safe, discuss this with the prescribing clinician
Who is Evorel Conti not suitable for?
Evorel Conti may not be suitable for some people. To make sure it’s safe for you, speak to the prescribing clinician before using Evorel Conti if you:
- Are allergic to the active ingredients estradiol or norethisterone acetate
- Have ever had breast cancer
- Have cancer sensitive to oestrogen
- Have untreated endometrial hyperplasia (an excessively thick womb lining)
- Suffer from a blood clots
- Suffer from porphyria
- Have had a heart attack, angina, stroke, or high blood pressure
- Have unusual vaginal bleeding
- Have liver disease or any other liver problems
- Are pregnant or breastfeeding
- Have fibroids
- Have uterine problems such as endometriosis or endometrial hyperplasia
- Have diabetes
- Suffer from migraines
- Have gallbladder disease
- Have asthma
- Have epilepsy
- Have fluid retention
- Have high cholesterol levels in the blood
- Are obese
- Have a hereditary ear disorder
How and where to get Evorel Conti?
You can buy Evorel Conti safely and securely from NowPatient. You can start a consultation today for free and if you qualify for treatment, you only pay for the cost of the medication. Delivery is made to your home or office from our registered pharmacy.
Our service is certified, safe and effective, and we only ever treat conditions. If you book a consultation with a prescribing clinician for the treatment of HRT, you can discuss if Evorel Conti is a suitable treatment option for you.
At the end of the consultation, the clinician will decide if a treatment plan is suitable for you. If it is, the clinician will issue you with a prescription which can then be ordered, paid for and delivered directly to your chosen address by NowPatient.
Dosage and strength for Evorel Conti patches for HRT
Evorel Conti patches contain 3.2mg of estradiol hemihydrate and 11.2mg of norethisterone acetate.
Information about how to use Evorel Conti for HRT
The Evorel Conti patch should be applied to a clean and dry area of skin. You may choose to apply the patch to your thighs or bottom. The patch must be changed twice a week, on the same two days each week. You should not apply the new patch to the same area of skin and do not apply the patch around your breasts. Read the patient information leaflet provided or speak to a healthcare professional for further information.
What happens if you use too much Evorel Conti?
If you use more than prescribed, then it can lead to some unpleasant side effects. You should talk to your doctor or reach out to one of our prescribing clinicians, if you have used too much Evorel Conti and you experience any of the following side effects:
What are the side effects of Evorel Conti?
Side effects of Evorel Conti are split into common and serious.
Common side effects include:
- Nausea
- Headache, dizziness
- Breast tenderness, breast pain
- Change in sex drive
- Anxiety, insomnia
- Stomach pain, indigestion, flatulence, diarrhoea
- Irregular bleeding
- Acne, skin irritation, rash
- Vaginal discharge
- Fluid retention, weight gain, bloating
Serious side effects include:
- Blood clots
- Stroke
- Heart disease – chest pain passing into the neck or arm
- Liver disease – jaundice (yellowing of the skin or eyes), abdominal pain
If you experience any serious side effects, you should contact NHS 111.
If you experience a serious allergic reaction with the signs shown below you should contact emergency services on 999.
- Your lips, mouth, throat or tongue suddenly become swollen
- You’re breathing very fast or struggling to breathe (you may become very wheezy or feel like you’re choking or gasping for air)
- Your throat feels tight or you’re struggling to swallow
- Your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet)
- You suddenly become very confused, drowsy or dizzy
- Someone faints and cannot be woken up
Always report adverse effects to the MHRA yellow card reporting system. You can read more about this here How and where do I report side effects of my medication? – NowPatient
Information about using Evorel Conti at the same time as other medications or herbal supplements
There is not enough evidence to suggest there are any drug interactions between herbal supplements and Evorel Conti. In any event, you should let your prescribing clinician know if you are taking any herbal supplements or other prescription drugs, such as:
- Phenytoin or carbamazepine
- Rifampicin
- Ritonavir or nelfinavir
- Warfarin
- St John’s Wort
Can Evorel Conti used for HRT be used long term?
HRT should only be used as a short-term treatment for the menopause. Women who use HRT for more than 5 years may be at an increased risk of ovarian cancer. Speak to your GP to review your treatment at least once each year and have regular checkups.
Is there a herbal Evorel Conti?
No. Herbal Evorel Conti does not exist. If you have been marketed such a formulation, it may be fake.
Should I avoid any particular food or drink when using Evorel Conti?
You can eat and drink normally when using Evorel Conti.
What lifestyle changes can I make to help me with HRT?
You modify your lifestyle in a number of ways, and this may have a positive impact on your symptoms:
- Using a fan
- Cool showers
- Light clothing
- Lubricants
- Healthy diet
- Regular exercise
- Quit smoking
Alternatives to Evorel Conti
Alternative HRT patches include Estaderm and Estradot patches.
Sources
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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FAQs
Answers to Popular Questions About Evorel Conti
What is Evorel Conti?
Evorel Conti is a combined continuous HRT patch containing oestradiol 50 mcg/24h and norethisterone acetate 170 mcg/24h. It delivers both hormones transdermally and is designed to be bleed-free for postmenopausal women (at least 12 months since last period). It is applied twice weekly and provides the benefits of transdermal HRT delivery — notably no increased VTE risk — with the convenience of a combined product.
How does Evorel Conti work?
Evorel Conti delivers a continuous dose of oestradiol to relieve menopausal symptoms and norethisterone to protect the endometrium. Because both hormones are delivered transdermally at a steady rate every day, the aim is to avoid monthly withdrawal bleeds. The transdermal route bypasses liver metabolism, avoiding the increased VTE risk associated with oral combined HRT.
How do I apply Evorel Conti patches?
Apply one patch to clean, dry skin on the lower trunk, buttocks, or thigh. Change the patch twice weekly (every 3–4 days). Press firmly for 10–15 seconds. Rotate the application site. The patch can be worn during bathing and exercise. Start a new patch as soon as you remove the old one — do not leave a gap between patches.
What are the side effects of Evorel Conti?
Common side effects include application site reactions (redness, itching), breast tenderness, headaches, and breakthrough bleeding or spotting, particularly in the first 3–6 months. If bleeding persists beyond 6 months, see your prescriber. The side effect profile is generally milder than oral combined HRT due to steady transdermal delivery.
Is Evorel Conti safer than oral combined HRT?
Transdermal delivery avoids the increased VTE risk associated with oral HRT, which is a significant safety advantage. However, the breast cancer risk associated with combined HRT (oestrogen + progestogen) applies regardless of the route of delivery. The lowest risk combined HRT is transdermal oestradiol with micronised progesterone (Utrogestan). Discuss options with your prescriber.
How can I get Evorel Conti?
Evorel Conti is available on NHS prescription from your GP, menopause clinic, or through NowPatient. It is a good option for postmenopausal women who prefer patches and need combined HRT.
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