Livial

Book a quick face-to-face video consultation with a certified prescribing pharmacist, nurse, or doctor. If approved, your Livial will be prescribed* and delivered straight to your door with free next-day delivery†. No hidden fees. No delays. Just expert care.

* Includes Free Private Prescription & Consultation.

† Applies to UK only.

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Manufactured by Organon
A box of Livial liquid tablets on a white background.
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MEDICAL INFORMATION

Livial Key Facts

Evorel, Femoston, Kliovance

About Livial

Livial tablets contain tibolone, which is broken down in the body into the female sex hormones oestrogen and progesterone. Livial also increases levels of testosterone, which helps to limit some of the side effects of hormone replacement therapy (HRT).

Livial is a HRT treatment used in postmenopausal women for the symptoms of menopause. If only estrogen levels are increased during HRT treatment, the endometrium would grow excessively, causing an increased risk of endometrial cancer. Livial helps to raise progesterone levels, reducing the risk of this side effect.

Livial helps to tteat menopausal symptoms such as:

  • Osteoporosis
  • Hot flushes, night sweats
  • Depression, mood swings
  • Sleep problems
  • Vaginal dryness

NowPatient offers Livial tablets as a treatment for HRT only, following an online consultation with a prescribing clinician.

Key facts of Livial

  • For the treatment of HRT
  • Livial has some common side effects which include nausea and headaches
  • Livial will not prevent pregnancy in otherwise fertile women
  • Do not use a hormonal contraceptive when treated with a HRT
  • It can be dangerous if you take Livial with certain medications. If you’re not sure if it is safe, discuss this with the prescribing clinician
  • Livial has a lower dose of oestrogen and progesterone and is more suitable for women who are more sensitive to hormones
  • Livial is most suited to women who have not had a natural period in the last 12 months

Who is Livial not suitable for?

Livial may not be suitable for some people. To make sure it’s safe for you, speak to the prescribing clinician before taking Livial if you:

  • Have hypersensitivity to the active ingredients estradiol hemihydrate or norethisterone acetate, or the inactive ingredients potato starch, lactose monohydrate, or magnesium stearate
  • Have ever had breast cancer
  • Have cancer sensitive to oestrogen
  • Have untreated endometrial hyperplasia (an excessively thick womb lining)
  • Suffer from a blood clots
  • Suffer from porphyria
  • Have had a heart attack, angina, stroke, or high blood pressure
  • Have unusual vaginal bleeding
  • Have liver disease or any other liver problems
  • Are pregnant or breastfeeding
  • Have fibroids
  • Have uterine problems such as endometriosis or endometrial hyperplasia
  • Have diabetes
  • Suffer from migraines
  • Have gallbladder disease
  • Have asthma
  • Have epilepsy
  • Have fluid retention
  • Have high cholesterol levels in the blood
  • Are obese
  • Have a hereditary ear disorder

How and where to get Livial?

You can buy Livial safely and securely from NowPatient. You can start a consultation today for free and if you qualify for treatment, you only pay for the cost of the medication. Delivery is made to your home or office from our registered pharmacy.

Our service is certified, safe and effective, and we only ever treat conditions. If you book a consultation with a prescribing clinician for the treatment of HRT, you can discuss if Livial is a suitable treatment option for you.

At the end of the consultation, the clinician will decide if a treatment plan is suitable for you. If it is, the clinician will issue you with a prescription which can then be ordered, paid for and delivered directly to your chosen address by NowPatient.

Dosage and strength for Livial tablets for HRT

Livial tablets contain 2.5 mg of tibolone as the active ingredient.

Information about how to take Livial for HRT

Livial tablets should be taken at the same time each day. Livial tablets are marked with the day of the week to help you remember when to take them. Swallow the tablets whole with water, with or without food. Start a new pack once you finish your current pack, without a break. Read the patient information leaflet provided or speak to a healthcare professional for further information.

What happens if you take too much Livial?

If you take more than prescribed, then it can lead to some unpleasant side effects. You should talk to your doctor or reach out to one of our prescribing clinicians, if you have taken too much Livial and you experience any of the following side effects:

What are the side effects of Livial?

Possible side effects of Livial are split into common and serious.

Common side effects include:

  • Nausea
  • Headache, dizziness
  • Breast tenderness, breast pain
  • Change in sex drive
  • Anxiety, insomnia
  • Stomach cramps, indigestion, flatulence, diarrhoea
  • Irregular bleeding
  • Acne, skin irritation, rash
  • Vaginal discharge
  • Fluid retention, weight gain, bloating
  • Infection

Serious side effects include:

  • Blood clots
  • Stroke
  • Heart disease – chest pain passing into the neck or arm
  • Liver disease – jaundice (yellowing of the skin or eyes), abdominal pain

If you experience any serious side effects, you should contact NHS 111.

If you experience a serious allergic reaction with the signs shown below you should contact emergency services on 999.

  • Your lips, mouth, throat or tongue suddenly become swollen
  • You’re breathing very fast or struggling to breathe (you may become very wheezy or feel like you’re choking or gasping for air)
  • Your throat feels tight or you’re struggling to swallow
  • Your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet)
  • You suddenly become very confused, drowsy or dizzy
  • Someone faints and cannot be woken up

Always report adverse effects to the MHRA yellow card reporting system. You can read more about this here How and where do I report side effects of my medication? – NowPatient

Information about taking Livial at the same time as other medications or herbal supplements

There is not enough evidence to suggest there are any drug interactions between herbal supplements and Livial. In any event, you should let your prescribing clinician know if you are taking any herbal supplements or other prescription drugs, such as:

  • Phenytoin or carbamazepine
  • Rifampicin
  • Ritonavir or nelfinavir
  • Warfarin
  • St John’s Wort

Can Livial taken for HRT be taken long term?

HRT should only be used as a short-term treatment for the menopause. Speak to your GP to review your treatment at least once each year and have regular checkups.

Is there a herbal Livial?

No. Herbal Livial does not exist. If you have been marketed such a formulation, it may be fake.

Can women use Livial?

Women can take Livial for HRT, but should speak to a doctor if considering taking it while pregnant or breastfeeding.

Should I avoid any particular food or drink when taking Livial?

You can eat and drink normally when taking Livial.

What lifestyle changes can I make to help me with HRT?

You modify your lifestyle in a number of ways, and this may have a positive impact on your symptoms:

  • Using a fan
  • Cool showers
  • Light clothing
  • Lubricants
  • Healthy diet
  • Regular exercise
  • Quit smoking

Alternatives to Livial

Alternative HRT treatments include Femoston, Evorel, and Premarin.

Sources

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

FAQs

Answers to Popular Questions About Livial

What is Livial?

Livial is a unique HRT product containing tibolone 2.5 mg. Tibolone is a synthetic steroid that has oestrogenic, progestogenic, and weak androgenic activity. It is used as a continuous, bleed-free HRT for postmenopausal women (at least 12 months since last period). Unlike conventional HRT that combines separate oestrogen and progestogen, tibolone acts as a single compound with tissue-selective activity. Livial is manufactured by Organon.

How does Livial work?

Tibolone is metabolised in the body into three active compounds with oestrogenic, progestogenic, and androgenic properties. The oestrogenic effects relieve menopausal symptoms and protect bone. The progestogenic effect protects the endometrium. The weak androgenic effect may help with low libido, which some postmenopausal women experience. Tibolone’s tissue-selective metabolism means it has minimal stimulatory effect on breast tissue and the endometrium.

What is the difference between Livial and standard HRT?

Livial differs from conventional HRT in several ways: it is a single compound rather than a combination product; it has androgenic as well as oestrogenic and progestogenic activity; it may have less breast tenderness than conventional HRT; and it may help with reduced sexual desire due to its androgenic component. However, it is generally less effective at relieving severe vasomotor symptoms than oestradiol-based HRT.

How do I take Livial?

Take one Livial tablet (2.5 mg) daily at the same time, continuously without a break. It should only be started at least 12 months after your last natural period. Swallow the tablet with water. It can be taken with or without food.

What are the side effects of Livial?

Common side effects include vaginal bleeding or spotting (particularly in the first months), abdominal pain, breast tenderness, and increased hair growth. Uncommon side effects include vaginal discharge, headache, migraine, dizziness, acne, and itching. Weight gain may occur. The androgenic effects may cause unwanted hair growth or acne in some women.

What are the risks of Livial?

Livial is associated with an increased risk of stroke, particularly in women over 60. It may also increase the risk of endometrial cancer and breast cancer recurrence (it should not be used in women with a history of breast cancer). The breast cancer risk with tibolone appears lower than with conventional combined HRT but higher than with oestrogen-only HRT. VTE risk may be slightly increased. Discuss all risks with your prescriber.

How can I get Livial?

Livial is available on NHS prescription from your GP, menopause specialist, or through online services like NowPatient. It may be particularly considered for women with low libido or those who do not tolerate conventional HRT. NowPatient offers online consultations and home delivery.

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