Mounjaro^®

Do you need a prescription for Mounjaro?

Yes, Mounjaro is only available with a valid physician Rx.

How much is Mounjaro without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase Mounjaro, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for Mounjaro in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a Mounjaro savings card?

Yes. Save up to 90% on your Mounjaro with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a Mounjaro coupon provider in the US?

No. Now Patient does not provide Mounjaro coupons or FREE Mounjaro samples.

Do you accept commercial, Medicare or Medicaid coverage for Mounjaro in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much Mounjaro?

US

Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using Mounjaro. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much Mounjaro. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.

UK

If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

US brand name of Mounjaro and manufacturer

Mounjaro is the brand name of tirzepatide and is available in the US under the brand name Mounjaro. It is manufactured by Eli Lilly

Source: Eli Lilly

UK brand name of Mounjaro and manufacturer

Mounjaro is the brand name of tirzepatide and is available in the UK under the brand name Mounjaro. It is manufactured by Eli Lilly.

Is Mounjaro available in the UK on the NHS?

Mounjaro is available on the NHS in the UK. It can be prescribed by healthcare providers for eligible patients.

Prescription requirement for Mounjaro

Mounjaro (tirzepatide) is available as Pen 0.5ml of 2.5mg/0.5ml, Pen 0.5ml of 5mg/0.5ml, Pen 0.5ml of 7.5mg/0.5ml, Pen 0.5ml of 10mg/0.5ml, Pen 0.5ml of 12.5mg/0.5ml and Pen 0.5ml of 15mg/0.5ml injection pen.  It is a prescription medicine and requires a valid prescription.

FDA approval of Mounjaro

Mounjaro has received FDA approval for:

• Treatment of adults with type 2 diabetes as an adjunct to diet and exercise

It is not known if MOUNJARO is safe and effective for use in children under 18 years of age.

It is not known if MOUNJARO can be used in people who have had pancreatitis.

When not to use Mounjaro?

There are certain precautions where Mounjaro may not be suitable if:

• You are allergic to tirzepatide or ingredients found in Mounjaro pen
• You have problems with your pancreas or kidney
• You have a history of diabetic retinopathy
• You are pregnant or breastfeeding or plan to become pregnant or breastfeed
• You or you family have had medullary thyroid carcinoma – MTC
• You have Multiple Endocrine Neoplasia syndrome type 2 -MEN 2
• You have severe problems with your stomach, such as slowed emptying of your stomach (gastroparesis) or problems digesting food
• You are taking insulin or sulfonylureas
• You take birth control pills by mouth? These may not work as well while using Mounjaro. Your healthcare provider may recommend another type of birth control when you start Mounjaro or when you increase your dose
• You have type 1 diabetes

Active ingredient of Mounjaro and mechanism of action

Mounjaro is the first and only approved treatment in a different class of medication for type 2 diabetes. The active ingredient in Mounjaro is tirzepatide. Tirzepatide is a glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonist. It is the first and only unimolecular dual GIP/GLP-1 receptor agonist. 

Both GIP and GLP-1 increase the production of insulin in your body. 

It has proven to result in significant reductions in A1c levels and body weight. Mounjaro works in several ways:

• It increases insulin production, but only when your blood sugar is rising—which makes the risk of low blood sugar minimal
• It decreases your liver’s production of sugar
• It slows down the speed at which your stomach empties food into your intestine. This helps manage your blood sugars after eating while also leaving you feeling full longer

Is Mounjaro as effective as Ozempic? 

Mounjaro is more effective than Ozempic (semaglutide) for blood sugar control and weight loss. For people taking Mounjaro, 82% reached an A1C under 7% on the 5-mg dose, 86% reached an A1C under 7% on the 10-mg dose, and 86% reached an A1C under 7% on the 15-mg dose. For people taking Ozempic 1-mg, 79% reached an A1C under 7%.

The American Diabetes Association (ADA) recommends that a reasonable goal for most adults with type 2 diabetes is an HbA1C less than 7%. 

Does Mounjaro reduce cardiovascular risks?

It is not yet proven, however there may be a follow-through assumption of the Novo Nordisk Phase III SELECT trial of Wegovy (semaglutide) which showed a statistically significant reduction in major adverse cardiovascular events (MACE) of 20%. Eli Lilly is sponsoring the CVOT in obese patients, SURMOUNT-MMO, which is expected to yield data in 2027.  

Can Mounjaro be used for weight loss?

Mounjaro is not currently FDA approved for weight loss or chronic weight management, despite data that shows that there is significant weight loss associated with using Mounjaro.  

In June 2023 Eli Lilly presented data from the Phase III SURMOUNT-2 study at the American Diabetes Association meeting, which showed a mean weight loss of 13.4% among patients receiving the 10mg dose and 15.7% for the 15mg dose after 72 weeks in overweight and obese patients with type 2 diabetes.

In August 2023, Eli Lilly confirmed that it had applied to the US Food and Drug Administration for the approval of Mounjaro for chronic weight management.

Some physicians and doctors are currently prescribing Mounjaro for weight loss, off-licence. 

‡Individual results may vary. In studies with or without other diabetes medications, weight loss in adults ranged from 12 lb (5 mg) to 25 lb (15 mg).

Can Mounjaro Pen be shared?

No. You should not share your Mounjaro pen with others, even if the needle is changed. You may give other people a serious infection or get a serious infection from them through cross-contamination.

Is it safe to use compounded Mounjaro?

The manufacturer has said that they do not sell Mounjaro or the active ingredient tirzepatide for compounding. Eli Lilly is the sole company that has FDA approval to market Mounjaro and it is supplied in a branded box that includes a proprietary pen along with FDA-approved prescribing information. Eli Lilly  cannot validate safety or effectiveness of products claiming to contain tirzepatide. Therefore, compounded Mounjaro should be avoided. While doctors can prescribe these medications “off-label” for obesity, insurance companies may deny these claims.

Is there a shortage of Mounjaro?

Mounjaro, in all strengths, is available to community pharmacies nationwide for treatment in patients with type 2 diabetes. There may be normal delays given the time required to order the product from their local distribution center, and geographical variabilities. However, there are concerns about supply effects, in anticipation of the manufacturer confirming it will be looking to licence the product for chronic weight management.

Forms of Mounjaro

Mounjaro comes as a solution in a prefilled, single-dose injection pen with the following dosage strengths:

• 2.5mg/0.5mL
• 5mg/0.5mL
• 7.5mg/0.5mL
• 10mg/0.5mL
• 12.5mg/0.5mL
• 15mg/0.5mL

Storage requirements for Mounjaro

Mounjaro is temperature sensitive and should be handled as follows: 

• Store your Pen in the refrigerator between 2C to 8C
• You may store your Pen at room temperature below 30C for up to a total of 21 days
• Do not freeze your Pen. If the Pen has been frozen, throw the Pen away and use a new Pen
• Store your Pen in the original carton to protect your Pen from light
• The Pen has glass parts. Handle it carefully. If you drop the Pen on a hard surface, do not use it. Use a new Pen for your injection
• Keep your MOUNJARO Pen and all medicines out of the sight and reach of children

Dosage of Mounjaro

Mounjaro is given as a weekly injection under the skin (subcutaneous). It should be administered at the same time each week, at any time of the day. The 2.5-mg dose is for treatment initiation and is not intended for glycemic (blood sugar) control. 

Patients are initiated with the 2.5-mg dose once weekly.

After 4 weeks on the 2.5-mg dose, the physician may increase to the 5-mg dose once weekly. If additional glycemic control is needed, the physician can continue to increase the dose by 2.5-mg increments after at least 4 weeks on the current dose. The maximum dose is 15 mg once weekly.

Source: Eli Lilly

Even though doses change, the administration frequency will always be weekly. It is important to follow the dosage instructions provided by your healthcare provider.

How long does it take for Mounjaro to start working?

Mounjaro starts working immediately. It achieves glycaemic control faster than other treatment. SURPASS-2 and SURPASS-3 studies have shown that those taking any dose of Mounjaro reached A1C targets about 4 weeks sooner than those using injected semaglutide (Ozempic) 1 mg. When compared to titrated insulin degludec (Tresiba), participants using Mounjaro achieved the A1C goals between 4 and 12 weeks sooner.

How do I use the Mounjaro Pen?

Follow these 4 steps to use your Mounjaro pen:

Step 1: Choose your injection site. Your healthcare provider can help you choose the injection site that is best for you. You or another person can inject the medicine in your stomach, thighs, or the back of your upper arms. Another person should give you the injection in the back of your upper arm.

Step 2: Pull off the base cap.

Step 3: Place the base flat on your skin, then unlock.

Step 4: Press and hold the button for up to 10 seconds. Listen for the first click. It means the injection has started. The second click means that the injection is complete.

How long can I continue using Mounjaro?

Mounjaro is designed to be a long-term maintenance treatment. Mounjaro is safe and effective when used as indicated for the treatment of adults with type 2 diabetes to lower blood sugar, along with diet and exercise.

What are the common side effects of Mounjaro?

• Nausea
• Diarrhea
• Decreased appetite
• Vomiting
• Constipation
• Indigestion
• Stomach pain

What are the serious side effects of Mounjaro?

• Sudden inflammation of your pancreas (pancreatitis)
• Severe diarrhea, nausea, or vomitin
• Low blood sugar (hyproglycemia)
• Serious allergic reactions
• Possible risk of thyroid cancer

Contact your healthcare provider if you experience any serious side effects.

What can I do if I experience nausea when using Mounjaro?

• Consume bland, low-fat foods, like crackers, toast, rice
• Eat smaller meals–try splitting your 3 daily meals into 4 or more smaller ones
• Stop eating when you feel full
• Avoid laying down after eating
• Avoid fat or fatty foods
• Drink ice-cold drinks

What support resources are there for Mounjaro?

You can contact the Mounjaro patient services support center at 1-833-807-MJRO (833-807-6576).

What prescription assistance is available for Ozempic?

Prescription drug prices can be confusing. Two people may pay different prices for the same drug, depending on their insurance situation. The list price of Mounjaro is $1,023.04 per fill, but the amount you pay will largely depend on your prescription drug insurance plan.

Commercially insured patients may be eligible for the Mounjaro Savings Card program.

If you are not eligible for the Mounjaro Savings Program, then you may have to pay close to the list price shown above, plus any additional pharmacy charges depending on where you purchase your medicine.

If you are interested in obtaining insurance, there are resources available to help you:

• To find out if you qualify for Medicaid and for information about copayments in your state, please visit: https://www.medicaid.gov/state-overviews/index.html
• To learn more about private individual policies via the Insurance Marketplace, please visit: https://mat.org/Health-Insurance-Resources

For the most accurate information, talk to your insurance provider who knows the details of your plan.

Interactions with other drugs

Ozempic may interact with certain medications, including:

• Insulin (Humalog, Tresiba, Lantus, Basaglar, Fiasp)
• Sulfonylureas (Amayrl, glyburide, glipizide)
• Meglitinides (repaglinide, nateglinide)
• Birth control pills (drospirenone/estetrol, ethinyl estradiol/norethindrone, ethinyl estradiol/norgestimate) 
• Ibuprofen
• Simvastatin
• Atorvastatin (Lipitor)

Sources

• FDA – Mounjaro
• Drugs.com – Mounjaro
• Eli Lilly – Mounjaro