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when will zepbound be available in pharmacies?

when will zepbound be available in pharmacies?

Navin Khosla NowPatientGreen tick
Updated on 7 Mar 2024

The anticipation for the release of the weight loss drug Zepbound, the new medication developed by American pharmaceutical company Eli Lilly and Company, is growing among adults living with certain medical conditions. Zepbound, also known as tirzepatide, has shown promising results in clinical trials, and patients are eagerly awaiting its availability in pharmacies. If you’ve heard of Mounjaro, you’ve heard of Zepbound, they contain the same active ingredient, but treat different indications. In this article, we will delve into the details of when Zepbound will be available in pharmacies, the benefits it offers, and how it can potentially improve the lives of those who need it.

Understanding Zepbound and its benefits

Zepbound, or tirzepatide, is an innovative medication developed by Lilly Pharmaceuticals for the treatment of specific medical conditions. It belongs to a class of drugs called glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and is designed to help manage blood sugar levels in adults living with type 2 diabetes. Additionally, Zepbound has shown potential benefits for individuals struggling with obesity. The drug joins a list of other similar prescription drugs that are FDA-approved (Food and Drug Administration). Like Novo Nordisk’s Ozempic and Wegovy containing the active ingredient semaglutide.

The unique mechanism of action of Zepbound sets it apart from other medications on the market. It combines the effects of two hormones, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP), to regulate blood sugar levels and promote weight loss. This dual action makes Zepbound a promising option for individuals who have not achieved adequate glycemic control with other treatments.

Zepbound is indicated for chronic weight management in adult patients with obesity with a BMI (body mass index) of 30+, or who are overweight with a BMI of 27+ with weight-related medical health conditions. Weight-related conditions may include high blood pressure (hypertension), type 2 diabetes, obstructive sleep apnea, cardiovascular disease or high cholesterol. It is typically prescribed in conjunction with a reduced-calorie diet and increased physical activity to help people lose weight and maintain weight loss. The most common side effects of Zepbound include nausea, diarrhea, vomiting, constipation, stomach (abdominal) pain, indigestion, and injection site reactions.

Clinical trials and efficacy

Extensive clinical trials have been conducted to evaluate the safety and efficacy of Zepbound in treating type 2 diabetes and obesity. The results have been highly encouraging, demonstrating significant improvements in glycemic control and weight loss.

In a phase 3 clinical trial involving over 4,000 patients with type 2 diabetes, Zepbound demonstrated superior efficacy compared to other GLP-1 RAs. The trial showed a substantial reduction in HbA1c levels, a key indicator of long-term glucose control, as well as significant weight loss. These findings highlight the potential of Zepbound to address the multifaceted challenges faced by individuals living with type 2 diabetes.

FDA approval process

The journey from clinical trials to the availability of a new medication in pharmacies involves various stages, including regulatory approval by the United States Food and Drug Administration (FDA). Lilly Pharmaceuticals has submitted a New Drug Application (NDA) to the FDA for Zepbound, seeking approval for its use in obesity treatment and type 2 diabetes.

The FDA rigorously reviews the safety and efficacy data provided by the pharmaceutical company as part of the NDA. This process ensures that the medication meets the necessary standards for patient use. While the FDA strives to complete the review process within a specific timeline, it is crucial to note that the duration may vary depending on the complexity of the application.

Anticipated availability in Pharmacies

Following the U.S. Food and Drug Administration (FDA) approval on Nov. 8, 2023, people living with obesity can now access Zepbound in six doses (2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg) through a prescription that can be filled at retail and mail-order pharmacies.

Patient Access Programs and Support

Recognizing the importance of patient access to innovative medications, Lilly Pharmaceuticals is dedicated to providing support and assistance to individuals who may benefit from Zepbound. Patient access programs, often initiated by pharmaceutical companies, aim to remove barriers that may hinder access to medications.

Lilly Pharmaceuticals intends to launch patient support programs concurrent with the availability of Zepbound in pharmacies. These programs may include financial assistance options, educational resources, and personalized support to help patients navigate their treatment journey effectively.

Consultation with Healthcare Providers

Before starting any new medication, patients need to consult with their healthcare providers. Healthcare professionals, such as doctors and pharmacists, have the expertise to assess an individual’s specific medical needs and determine if Zepbound is the right choice for chronic weight management.

During the consultation, healthcare providers will consider various factors, including the patient’s medical history, current medications, and treatment goals. They will evaluate the potential benefits and risks of Zepbound and guide its appropriate usage. Engaging in open and honest communication with healthcare providers is key to optimizing treatment outcomes.


Lilly’s Zepbound holds great promise for individuals living with type 2 diabetes and obesity. Its innovative mechanism of action and impressive clinical trial results have generated excitement within the medical community and among patients.

Zepbound is now available in pharmacies. Individuals are encouraged to consult with their healthcare providers to explore the best treatment options available. By working together, patients and healthcare professionals can navigate the journey towards optimal health and well-being.

Disclaimer: This article is for informational purposes only and should not be considered medical advice. Please consult with your healthcare provider for personalized recommendations and guidance.


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NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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