Avomine
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Other Related Treatments
MEDICAL INFORMATION
Avomine Key Facts
Other Related Names or Treatments
Phenergan
About Avomine
Avomine tablets contain the sedating antihistamine promethazine teoclate as the active ingredient. Promethazine is an anti-emetic (anti-sickness) drug that is used to treat insomnia, allergies such as hay fever, symptoms of the common cold (mixed with paracetamol, dextromethorphan or pseudoephedrine), and the prevention of travel sickness.
Avomine is alao available as alternative brands of promethazine such as Sominex and Phenergan. NowPatient offers Avomine as a treatment for travel sickness only, following an online consultation with a prescribing clinician.
Key facts of Avomine
- For the treatment of motion sickness
- Take Avomine the night before a long journey or 1 or 2 hours before a short journey
- Avomine has some common side effects which include drowsiness, headaches, and dizziness
- Do not drink alcohol when taking Avomine as this may increase the risk of side effects
- It can be dangerous if you take Avomine with certain medications like sleeping tablets. If you’re not sure if it is safe, discuss this with the prescribing clinician
Who is Avomine suitable for?
Avomine is suitable for most adults.
Who is Avomine not suitable for?
Avomine may not be suitable for some people. To make sure it’s safe for you, speak to the prescribing clinician before taking Avomine if you:
- Have previously had an allergic reaction to promethazine, or other phenothiazines or any of the other ingredients (sodium metabisulphite, lactose)
- Have glaucoma
- Have epilepsy
- Have liver, kidney or bladder problems
- Are pregnant or trying to get pregnant. Promethazine can affect home pregnancy tests
How and where to get Avomine 25mg tablets?
You can buy Avomine safely and securely from NowPatient. You can start a consultation today for free and if you qualify for treatment, you only pay for the cost of the medication. Delivery is made to your home or office from our registered pharmacy.
Our service is certified, safe and effective, and we only ever treat conditions. If you book a consultation with a prescribing clinician for the treatment of motion sickness, you can discuss if Avomine is a suitable treatment option for you.
At the end of the consultation, the clinician will decide if a treatment plan is suitable for you. If it is, the clinician will issue you with a prescription which can then be ordered, paid for and delivered directly to your chosen address by NowPatient.
Dosage and strength for Avomine for travel sickness
Avomine is available as 25mg tablets when used for the treatment of travel sickness.
Information about how to take Avomine for travel sickness
For the prevention of motion sickness, take 25mg 1 or 2 hours before a short journey or 25mg the night before a long journey. When treating motion sickness, take 25mg immediately and 25mg the same evening, then 25mg the next day, if needed. Read the patient information leaflet supplied with your medication for further information.
What happens if you take too much Avomine?
If you take more than prescribed, then it can lead to some unpleasant side effects.
You should talk to your doctor or reach out to one of our prescribing clinicians, if you have taken too much Avomine and you experience any of the following side effects:
- Feeling very drowsy
- An irregular heartbeat
- Difficulty breathing
In serious cases, you can become unconscious or have seizures or fits and may need emergency treatment in hospital.
What are the side effects of Avomine?
Side effects of Avomine are split into common and serious.
Common side effects include:
- Daytime tiredness
- Blurred vision
- Upset stomach, loss of appetite, diarrhoea
- Nightmares
- Dizziness
- Headaches
- Skin sensitivity to sunlight
- If you’re over 65, side effects may include confusion, dry mouth, blurred vision, and difficulty urinating
Serious side effects include:
- Yellowing of your eyes which may be a sign of liver problems
- Bruising or bleeding easily
- Muscle stiffness or shaking
- Unusual face or tongue movements
If you experience any serious side effects, you should contact NHS 111.
If you experience a serious allergic reaction with the signs shown below you should contact emergency services on 999.
- Your lips, mouth, throat or tongue suddenly become swollen
- You’re breathing very fast or struggling to breathe (you may become very wheezy or feel like you’re choking or gasping for air)
- Your throat feels tight or you’re struggling to swallow
- Your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet)
- You suddenly become very confused, drowsy or dizzy
- Someone faints and cannot be woken up
Always report adverse effects to the MHRA yellow card reporting system. You can read more about this here: how and where do i report side effects of my medication
Information about taking Avomine at the same time as other medications or herbal supplements
There may be problems when taking herbal supplements with promethazine, especially those that cause sleepiness, or dry mouth. Also tell your doctor if you are taking:
- Monoamine oxidase inhibitors (MAOIs), such as phenelzine
- Opioids, such as codeine, morphine, or oxycodone
Also, speak with a healthcare professional before you take Avomine with any other painkillers or medicines.
How long does Avomine take to work?
Avomine will start to work within 20 minutes and may continue to work for up to 12 hours.
Can Avomine be taken long term?
You should only take promethazine for short periods, unless your doctor says it’s ok to take it longer.
Is Avomine addictive?
Promethazine, the active ingredient in Avomine is not addictive, but do not take it for longer than advised. If you have taken promethazine for a long time and suddenly stop, you may feel dizzy or sick. Speak to your doctor before stopping promethazine if you have taken it for a long time.
Is there a herbal Avomine?
No. Herbal Avomine does not exist. If you have been marketed such a formulation, it may be fake.
Can women use Avomine when pregnant or breastfeeding?
Yes. Avomine is not harmful to your baby. Also, if your doctor says your baby is healthy, promethazine can be used during breastfeeding.
Should I avoid any particular food or drink when taking Avomine?
You can eat and drink normally when taking Avomine. However, do not drink alcohol when taking Avomine as this may increase the risk of side effects.
Alternatives to Avomine
Alternatives for the treatment of motion sickness include Phenergan.
Sources
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
FAQs
Answers to Popular Questions About Avomine
What is Avomine?
Avomine is a brand-name medication containing promethazine teoclate 25 mg. It is an antihistamine used primarily for the prevention and treatment of motion sickness (travel sickness) and nausea. Avomine belongs to the phenothiazine class of antihistamines and works by blocking histamine H1 receptors and muscarinic receptors in the brain’s vomiting centre. It is available over the counter in the UK from pharmacies and can also be obtained on prescription. Avomine is suitable for adults and children aged 5 years and over.
What is the difference between Avomine and Phenergan?
Both Avomine and Phenergan contain forms of promethazine, but they use different salts. Avomine contains promethazine teoclate, which is specifically formulated for motion sickness and has a longer duration of action (up to 24 hours). Phenergan contains promethazine hydrochloride, which has a wider range of uses including allergies, sleep, and general nausea. For travel sickness specifically, Avomine (promethazine teoclate) is generally preferred as it provides longer-lasting protection with a single dose taken the night before or 1–2 hours before travel.
How does Avomine work?
Avomine works by blocking histamine H1 receptors and muscarinic acetylcholine receptors in the vomiting centre and vestibular system of the brain. Motion sickness occurs when the brain receives conflicting signals from the eyes, inner ears, and body about movement and position. By blocking these receptors, Avomine reduces the sensitivity of the balance organs in the inner ear and suppresses the brain’s nausea and vomiting response. It also has a sedative effect, which can be beneficial during long journeys.
How should I take Avomine for travel sickness?
For preventing travel sickness, take one Avomine 25 mg tablet the night before a long journey, or 1–2 hours before a shorter journey. If the journey lasts longer than 24 hours, you can take another tablet at bedtime. For treatment of motion sickness that has already started, take one 25 mg tablet as soon as possible, then another at bedtime if needed. The maximum dose for adults is 75 mg in 24 hours. Avomine tablets should be swallowed whole with water.
What is the dose of Avomine for children?
Avomine is suitable for children aged 5–10 years at a dose of half a 25 mg tablet (12.5 mg) the night before travel or 1–2 hours before the journey. Children aged 10 years and over can take the adult dose of one 25 mg tablet. Avomine should not be given to children under 5 years of age. Always follow the dose instructions provided with the medication. If you are unsure about the correct dose for your child, ask a pharmacist or doctor.
Can I take Avomine on an empty stomach?
Yes, Avomine can be taken with or without food. However, if you experience stomach discomfort, taking it with a light snack or a glass of milk may help. For motion sickness prevention, the most important factor is timing rather than food — take the tablet well in advance of travel (ideally the night before for long journeys) to allow the medication to reach effective levels before exposure to motion.
What are the common side effects of Avomine?
The most common side effect of Avomine is drowsiness, which can be significant and may persist into the following day. Other common side effects include dry mouth, blurred vision, dizziness, headache, and difficulty concentrating. Less common side effects include constipation, urinary retention, and skin reactions. In children, paradoxical excitation (restlessness and agitation rather than drowsiness) can occasionally occur. The sedative effect may be considered a benefit for long journeys but can impair driving and concentration.
Will Avomine make me drowsy?
Yes, drowsiness is the most common side effect of Avomine and is often quite pronounced. It is a sedating antihistamine. You should not drive, operate heavy machinery, or perform activities requiring mental alertness until you know how Avomine affects you. The drowsiness may last for several hours and can persist into the following day. Avoid combining Avomine with alcohol or other sedating medications, as this significantly increases drowsiness. For some people, the sedation is a welcome side effect on long flights or journeys.
What medications interact with Avomine?
Avomine can interact with several medications. CNS depressants including alcohol, opioids, benzodiazepines, and other sedating antihistamines increase the risk of excessive drowsiness. Anticholinergic medications (such as tricyclic antidepressants, hyoscine) may enhance side effects like dry mouth and blurred vision. Avomine may mask the warning signs of ototoxicity from aminoglycoside antibiotics. It may also interfere with pregnancy testing and allergy skin prick tests. Inform your pharmacist or prescriber of all current medications.
Can I buy Avomine without a prescription?
Yes, Avomine is available over the counter (OTC) from pharmacies in the UK without a prescription for the prevention and treatment of motion sickness. A pharmacist will ask you some questions to ensure it is suitable for you. It is also available on prescription from your GP or through online services like NowPatient. If you prefer the convenience of home delivery or need advice on the best travel sickness medication for your circumstances, NowPatient can help.
Is Avomine safe during pregnancy?
Promethazine (the active ingredient in Avomine) has been widely used in pregnancy and is generally considered to have a reassuring safety profile. It is sometimes used to manage hyperemesis gravidarum (severe pregnancy sickness). However, it should only be used in pregnancy when advised by a doctor, and the lowest effective dose should be taken for the shortest time needed. Avomine should be avoided near the end of pregnancy as it may cause sedation or other effects in the newborn. Speak to your doctor or midwife before using Avomine if you are pregnant.
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