Used for Menopause

View progesterone savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or progesterone Patient Assistance Program.

Programs are suitable for individuals who want to buy progesterone without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by various FDA-approved generic manufacturers.

*Applicable to Drug Coupons & Patient Assistance Programs

This content is intended for US audiences only

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    Save up to 90%

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Updated on 24 Apr 2024

Learn more about progesterone

What dosages is progesterone available in?

What dosages is progesterone available in?

progesterone is available as a 4% and 8% vaginal gel.

What is progesterone used for?

What is progesterone used for?

progesterone is a progesterone and is used for the following:
Female infertility Lack of menstrual periods

How does progesterone work?

How does progesterone work?

progesterone contains the natural sex hormone progesterone. It restarts menstrual periods by helping to balance the natural levels of progesterone in the body. When used for fertility treatments, it prepares the uterus to receive and nourish an embryo.

How do I take progesterone?

How do I take progesterone?

progesterone is dosed as follows:

  • Fertility treatment: Insert 90 mg of the 8% gel into your vagina 1 to 2 times a day. If you successfully become pregnant, you will continue using this medication for 10 to 12 weeks
  • Lack of menstrual periods: Insert 45 mg of the 4% gel into your vagina every other day for 6 doses. If needed, the dose can be raised to 90 mg of the 8% gel every other day
Is it safe for me to take progesterone?

Is it safe for me to take progesterone?

progesterone is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. progesterone should not be used in individuals with any of the following conditions:
Known sensitivity to progesterone (progesterone or any of the other ingredients).

  • Undiagnosed vaginal bleeding
  • Liver dysfunction or disease
  • Known or suspected malignancy of the breast or genital organs.Missed abortion
  • Active thrombophlebitis or thromboembolic disorders, or a history of hormone-associated thrombophlebitis or thromboembolic disorders
progesterone Common Side Effects

progesterone Common Side Effects

Common side effects of progesterone:

  • Breast growth
  • Sleepiness
  • Constipation
  • Mood swings
  • Nausea
  • Headache
  • Depression
  • Trouble sleeping
  • Pain around the vaginal opening
  • Nervousness
  • Cramps
  • Breast pain
  • Urinating in the middle of the night
  • Stomach pain
  • Lowered sex drive
progesterone Serious Side Effects

progesterone Serious Side Effects

Serious side effects are rare with progesterone. Contact your healthcare provider immediately if you experience any of the following.

  • Allergic reactions
  • Heart attack: Chest pain or tightness, pain that radiates up to your shoulder, arm, neck, or jaw
  • Stroke: Sudden trouble talking, trouble walking, numbness on one side of your body or face
  • Shortness of breath
  • Sudden, severe headaches
Effects of other drugs, drug classes and over-the-counter products on progesterone

Effects of other drugs, drug classes and over-the-counter products on progesterone

There are no major drug interactions listed for progesterone. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.

Who makes progesterone?

Who makes progesterone?

Various FDA-approved generic manufacturers

Is progesterone safe in pregnancy?

Is progesterone safe in pregnancy?

progesterone 8% is also used as part of a program for women who are undergoing fertility treatments to get pregnant. Progesterone is one of the hormones that helps to prepare the lining of your uterus so that it is ready to receive and nourish a fertilized egg and to continue a pregnancy. If you are undergoing ART treatment and your doctor has determined your body does not produce enough progesterone on its own, progesterone may be prescribed to increase your progesterone. If pregnancy occurs, progesterone may be supplemented for 10-12 weeks until
production of progesterone by the placenta is adequate.


What to do if you missed your progesterone dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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