CRINONE
Used for Menopause
Are you tired of high medication costs? Our service offers unbeatable savings on your CRINONE prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.
Manufactured by Watson Pharma
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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CRINONE key facts
What is CRINONE?
CRINONE is the brand name for progesterone and is available as a vaginal gel.
What dosages is CRINONE available in?
CRINONE is available as a 4% and 8% vaginal gel.
What is CRINONE used for?
CRINONE is a progesterone and is used for the following:
Female infertility Lack of menstrual periods
How does CRINONE work?
CRINONE contains the natural sex hormone progesterone. It restarts menstrual periods by helping to balance the natural levels of progesterone in the body. When used for fertility treatments, it prepares the uterus to receive and nourish an embryo.
How do I take CRINONE?
CRINONE is dosed as follows:
- Fertility treatment: Insert 90 mg of the 8% gel into your vagina 1 to 2 times a day. If you successfully become pregnant, you will continue using this medication for 10 to 12 weeks
- Lack of menstrual periods: Insert 45 mg of the 4% gel into your vagina every other day for 6 doses. If needed, the dose can be raised to 90 mg of the 8% gel every other day
Is it safe for me to take CRINONE?
CRINONE is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. CRINONE should not be used in individuals with any of the following conditions:
Known sensitivity to Crinone (progesterone or any of the other ingredients).
- Undiagnosed vaginal bleeding
- Liver dysfunction or disease
- Known or suspected malignancy of the breast or genital organs.Missed abortion
- Active thrombophlebitis or thromboembolic disorders, or a history of hormone-associated thrombophlebitis or thromboembolic disorders
CRINONE Common Side Effects
Common side effects of CRINONE:
- Breast growth
- Sleepiness
- Constipation
- Mood swings
- Nausea
- Headache
- Depression
- Trouble sleeping
- Pain around the vaginal opening
- Nervousness
- Cramps
- Breast pain
- Urinating in the middle of the night
- Stomach pain
- Lowered sex drive
CRINONE Serious Side Effects
Serious side effects are rare with CRINONE. Contact your healthcare provider immediately if you experience any of the following.
- Allergic reactions
- Heart attack: Chest pain or tightness, pain that radiates up to your shoulder, arm, neck, or jaw
- Stroke: Sudden trouble talking, trouble walking, numbness on one side of your body or face
- Shortness of breath
- Sudden, severe headaches
Effects of other drugs, drug classes and over-the-counter products on CRINONE
There are no major drug interactions listed for CRINONE. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes CRINONE?
Watson Pharma
Is CRINONE safe in pregnancy?
CRINONE 8% is also used as part of a program for women who are undergoing fertility treatments to get pregnant. Progesterone is one of the hormones that helps to prepare the lining of your uterus so that it is ready to receive and nourish a fertilized egg and to continue a pregnancy. If you are undergoing ART treatment and your doctor has determined your body does not produce enough progesterone on its own, Crinone may be prescribed to increase your progesterone. If pregnancy occurs, CRINONE may be supplemented for 10-12 weeks until
production of progesterone by the placenta is adequate.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my CRINONE prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your CRINONE prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient CRINONE savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient CRINONE savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for CRINONE | Canadian Prescription Savings* for CRINONE | CRINONE Drug Coupon* | CRINONE Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of CRINONE?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for CRINONE | Canadian Prescription Savings* for CRINONE | CRINONE Drug Coupon* | CRINONE Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the CRINONE savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the CRINONE drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for CRINONE, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the CRINONE prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, CRINONE is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed CRINONE for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the CRINONE prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the CRINONE prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for CRINONE
If you are having trouble paying for your CRINONE medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for CRINONE you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- CRINONE is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers CRINONE
- If CRINONE is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for CRINONE
If you are having trouble paying for your CRINONE medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for CRINONE you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers CRINONE
- If CRINONE is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for CRINONE
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your CRINONE treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for CRINONE you will need to meet the following criteria:
- You must be currently insured and have coverage for CRINONE
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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