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Prometrium is the brand name for progesterone and is available as an oral capsule.

Prometrium is available as 100 mg and 200 mg oral capsule.

Prometrium is a progesterone that is used to treat a lack of menstrual periods due to hormone imbalance.

Prometrium contains the hormone progesterone. It regulates menstrual periods by helping to balance the natural levels of the hormone progesterone in the body. When taken together with estrogen-containing medications, it helps protect the uterus from the damage caused by estrogen.

Prometrium is typically taken as 200 mg to 400 mg by mouth once a day at bedtime. Your length of therapy will depend on the condition being treated.

Prometrium is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. Prometrium should not be used in women with any of the following conditions:

• Prometrium should not be used in patients with known hypersensitivity to its ingredients. Prometrium contain peanut oil and should never be used by patients allergic to peanuts
• Undiagnosed abnormal genital bleeding
• Known, suspected, or history of breast cancer
• Active deep vein thrombosis, pulmonary embolism or history of these conditions
• Active arterial thromboembolic disease (for example, stroke and myocardial infarction), or a history of
  these conditions
• Known liver dysfunction or disease.
• Known or suspected pregnancy

Common side effects of Prometrium:

• Headache
• Breast tenderness
• Joint pain
• Depression
• Dizziness
• Stomach bloating
• Hot flashes
• Trouble urinating
• Stomach pain
• More vaginal discharge than usual

Serious side effects are rare with Prometrium. Contact your healthcare provider immediately if you experience any of the following.

• Allergic reactions: trouble breathing, hives, swelling of your face, lips, tongue, or throat
• Heart attack: Chest pain or tightness, pain that radiates up to your shoulder, arm, neck, or jaw
• Stroke: Sudden trouble talking, trouble walking, or numbness on one side of your body or face
• Shortness of breath
• Sudden, severe headaches
• Breast lumps or pain
• Unusual or heavy vaginal bleeding

The following medications may interact with Prometrium:

• The metabolism of Prometrium was inhibited by ketoconazole. Ketoconazole is a known inhibitor of cytochrome P450 3A4, hence these data suggest that ketoconazole or other known inhibitors of this enzyme may increase the bioavailability of progesterone

Abbott Laboratories

Prometrium should not be used during pregnancy.

• Progesterone