HUMALOG MIX 50/50
Used for Type 2 Diabetes and Type 1 Diabetes
Are you tired of high medication costs? Our service offers unbeatable savings on your HUMALOG MIX 50/50 prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.
Manufactured by Eli Lilly & Company
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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HUMALOG MIX 50/50 key facts
What is HUMALOG MIX 50/50?
HUMALOG MIX 50/50 is the brand name for insulin lispro protamine and insulin lispro and is available as a subcutaneous injection.
What dosages is HUMALOG MIX 50/50 available in?
HUMALOG MIX 50/50 is available as a subcutaneous injection that contains 100 units/mL (U-100), 50% insulin lispro protamine and 50% insulin lispro.
What is HUMALOG MIX 50/50 used for?
HUMALOG MIX 50/50 is an insulin and is used for the following:
- Type 1 diabetes
- Type 2 diabetes
How does HUMALOG MIX 50/50 work?
HUMALOG MIX 50/50 releases a hormone called insulin into the body to lower glucose (sugar) levels in the blood.
How do I take HUMALOG MIX 50/50?
- Inject HUMALOG MIX 50/50 subcutaneously (within 15 minutes before a meal) in abdominal wall, thigh, upper arm, or buttocks and rotate injection sites to reduce the risk of lipodystrophy and localized cutaneous amyloidosis
- Individualize and adjust dosage based on metabolic needs, blood glucose monitoring results and glycemic control goal
Is it safe for me to take HUMALOG MIX 50/50?
HUMALOG MIX 50/50 is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have symptoms of hypoglycemia (low blood sugar).
HUMALOG MIX 50/50 Common Side Effects
Common side effects of HUMALOG MIX 50/50:
- Low blood sugar
- Injection site reaction (e.g., redness, swelling, itching)
- Changes in skin shape at the site of the injection
- Weight gain
- Swelling in the hands and feet
- Itching
- Rash
HUMALOG MIX 50/50 Serious Side Effects
Serious side effects are rare with HUMALOG MIX 50/50. Contact your healthcare provider immediately if you experience any of the following.
- Severe hypoglycemia (dangerously low blood sugar): if not treated, severe hypoglycemia can lead to unconsciousness, seizures, and even death
- Severe allergic reactions: rash, hives, swelling of face, tongue, and throat, difficulty breathing
- Dangerously low levels of potassium: if not treated, it can lead to difficulty breathing, irregular heartbeat, and even death
Effects of other drugs, drug classes and over-the-counter products on HUMALOG MIX 50/50
The following medications may interact with HUMALOG MIX 50/50:
- Drugs that may increase the risk of hypoglycemia: antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors pentoxifylline, pramlintide, salicylates, somatostatin analog (e.g. octreotide), and sulfonamide antibiotics
- Drugs that may decrease the blood glucose lowering effect: atypical antipsychotics, corticosteroids, danazol, diuretics estrogens, glucagon, isoniazid, niacin, oral contraceptives
- phenothiazines, progestogens (e.g., in oral contraceptives) protease inhibitors, somatropin, sympathomimetic agents (e.g. albuterol, epinephrine, terbutaline), and thyroid hormones
- Drugs that may increase or decrease the blood glucose lowering effect: alcohol, beta-blockers, clonidine, lithium salts, and pentamidine
- Drugs that may blunt the signs and symptoms of hypoglycemia: beta-blockers, clonidine, guanethidine, and reserpine
Who makes HUMALOG MIX 50/50?
Eli Lilly & Company
Is HUMALOG MIX 50/50 safe in pregnancy?
Published studies with HUMALOG MIX 50/50 used during pregnancy have not reported an association between insulin lispro and the induction of major birth defects, miscarriage, or adverse maternal or fetal outcomes. If you become pregnant while receiving HUMALOG MIX 50/50, talk to your healthcare provider.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my HUMALOG MIX 50/50 prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your HUMALOG MIX 50/50 prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient HUMALOG MIX 50/50 savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient HUMALOG MIX 50/50 savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for HUMALOG MIX 50/50 | Canadian Prescription Savings* for HUMALOG MIX 50/50 | HUMALOG MIX 50/50 Drug Coupon* | HUMALOG MIX 50/50 Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of HUMALOG MIX 50/50?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for HUMALOG MIX 50/50 | Canadian Prescription Savings* for HUMALOG MIX 50/50 | HUMALOG MIX 50/50 Drug Coupon* | HUMALOG MIX 50/50 Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the HUMALOG MIX 50/50 savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the HUMALOG MIX 50/50 drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for HUMALOG MIX 50/50, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the HUMALOG MIX 50/50 prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, HUMALOG MIX 50/50 is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed HUMALOG MIX 50/50 for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the HUMALOG MIX 50/50 prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the HUMALOG MIX 50/50 prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for HUMALOG MIX 50/50
If you are having trouble paying for your HUMALOG MIX 50/50 medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for HUMALOG MIX 50/50 you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- HUMALOG MIX 50/50 is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers HUMALOG MIX 50/50
- If HUMALOG MIX 50/50 is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for HUMALOG MIX 50/50
If you are having trouble paying for your HUMALOG MIX 50/50 medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for HUMALOG MIX 50/50 you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers HUMALOG MIX 50/50
- If HUMALOG MIX 50/50 is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for HUMALOG MIX 50/50
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your HUMALOG MIX 50/50 treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for HUMALOG MIX 50/50 you will need to meet the following criteria:
- You must be currently insured and have coverage for HUMALOG MIX 50/50
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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You can lower the cost of your prescription medications using our various savings programs which include drug coupons, savings card and manufacturer-sponsored patient assistance programs.
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