insulin lispro protamine/insulin lispro
Used for Type 2 Diabetes and Type 1 Diabetes
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Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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insulin lispro protamine/insulin lispro Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is insulin lispro protamine/insulin lispro available in?
HUMALOG MIX 75/25 is available as a subcutaneous injection that contains 100 units/mL (U-100), 75% insulin lispro protamine and 25% insulin lispro.
What is insulin lispro protamine/insulin lispro used for?
insulin lispro protamine/insulin lispro is an insulin and is used for the following:
- Type 1 diabetes
- Type 2 diabetes
How does insulin lispro protamine/insulin lispro work?
insulin lispro protamine/insulin lispro is an insulin. Insulin is a natural hormone your body normally makes to lower glucose (sugar) levels in the blood. It helps your body absorb and store sugar and fat from your bloodstream after eating a meal.
How do I take insulin lispro protamine/insulin lispro?
- The dose of HUMALOG MIX 75/25 will be different for each person. The dose depends on whether you’re using it for type 1 diabetes or type 2 diabetes, your weight, how well you respond to insulin, and your blood sugar levels Please follow the directions from your provider carefully.
- HUMALOG MIX 75/25 is typically dosed twice a day (with each dose meant to cover 2 meals or a meal and a snack). It should be injected under the skin within 15 minutes before a meal
Is it safe for me to take insulin lispro protamine/insulin lispro?
insulin lispro protamine/insulin lispro is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have symptoms of hypoglycemia.
insulin lispro protamine/insulin lispro Common Side Effects
Common side effects of insulin lispro protamine/insulin lispro:
- Low blood sugar (hypoglycemia)
- Allergic reactions
- Injection site reaction (e.g., redness, swelling, itching)
- Changes in skin shape at the site of the injection
- Weight gain
- Swelling (edema)
- Itching
- Rash
insulin lispro protamine/insulin lispro Serious Side Effects
Serious side effects are rare with insulin lispro protamine/insulin lispro. Contact your healthcare provider immediately if you experience any of the following.
- Severe hypoglycemia (dangerously low blood sugar): if not treated, severe hypoglycemia can lead to unconsciousness, seizures, and even death
- Severe allergic reactions: rash, hives, swelling of face, tongue, and throat, difficulty breathing
- Dangerously low levels of potassium: if not treated, it can lead to difficulty breathing, irregular heartbeat, and even death
Effects of other drugs, drug classes and over-the-counter products on insulin lispro protamine/insulin lispro
The following medications may interact with insulin lispro protamine/insulin lispro:
- Drugs that may increase the risk of hypoglycemia: antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors
- pentoxifylline, pramlintide, salicylates, somatostatin analog (e.g. octreotide), and sulfonamide antibiotics
- Drugs that may decrease the blood glucose lowering effect: atypical antipsychotics, corticosteroids, danazol, diuretics estrogens, glucagon, isoniazid, niacin, oral contraceptives phenothiazines, progestogens (e.g., in oral contraceptives) protease inhibitors, somatropin, sympathomimetic agents (e.g. albuterol, epinephrine, terbutaline), and thyroid hormones
- Drugs that may increase or decrease the blood glucose lowering effect: alcohol, beta-blockers, clonidine, lithium salts, and pentamidine.
- Drugs that may blunt the signs and symptoms of hypoglycemia: beta-blockers, clonidine, guanethidine, and reserpine
Who makes insulin lispro protamine/insulin lispro?
Various FDA-approved generic manufacturers
Is insulin lispro protamine/insulin lispro safe in pregnancy?
Published studies with HUMALOG MIX 75/25 used during pregnancy have not reported an association between insulin lispro and the induction of major birth defects, miscarriage, or adverse maternal or fetal outcomes. If you become pregnant while receiving HUMALOG MIX 75/25, talk to your healthcare provider.
What is the brand name for insulin lispro protamine/insulin lispro?
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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