Buy Loceryl Nail Lacquer Online. No Consultation Fee, Free Next-Day Delivery
Get prescribed Loceryl Nail Lacquer for Fungal Nail Infections by a UK clinician through a free video consultation*. No questionnaires, no hidden fees. You only pay for your medication if approved.


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MEDICAL INFORMATION
Loceryl Nail Lacquer Key Facts
Other Related Names or Treatments
Curanail
About Loceryl Nail Lacquer
Loceryl 5% Nail Lacquer contains the active ingredient amorolfine hydrochloride, an antifungal agent that kills a wide range of fungi that may cause fungal nail infections.
Loceryl is a nail treatment available with a prescription and is also available as the brand Curanail over the counter. NowPatient offers Loceryl as a treatment for fungal nail infections only, following an online consultation with a prescribing clinician.
Key facts of Loceryl Nail Lacquer
- For the treatment of fungal nail infections
- Loceryl can be used up to 3 months to clear a fungal nail infection
- Loceryl has some common side effects which include nail discolouration and brittle nails
- Artificial nails and nail polish should not be used while using Loceryl
Who is Loceryl suitable for?
Loceryl is suitable for adults and children over the age of 12.
Who is Loceryl not suitable for?
Loceryl may not be suitable for some people. To make sure it’s safe for you, speak to the prescribing clinician before using Loceryl if you:
- Are allergic to amorolfine or any of the other ingredients of Loceryl
- Are pregnant, plan to become pregnant or are breast-feeding
How and where to get Loceryl Nail Lacquer?
You can buy Loceryl Nail Lacquer safely and securely from NowPatient. You can start a consultation today for free and if you qualify for treatment, you only pay for the cost of the medication. Delivery is made to your home or office from our registered pharmacy.
Our service is certified, safe and effective, and we only ever treat conditions. If you book a consultation with a prescribing clinician for the treatment of fungal nail infections, you can discuss if Loceryl is a suitable treatment option for you.
At the end of the consultation, the clinician will decide if a treatment plan is suitable for you. If it is, the clinician will issue you with a prescription which can then be ordered, paid for and delivered directly to your chosen address by NowPatient.
Dosage and strength for Loceryl for fungal nail infections
Loceryl is available as a solution containing 5% amorolfine when used for the treatment of fungal nail infections.
Information about how to use Loceryl for fungal nail infections
Loceryl should be applied to the affected toe nails once or twice a weekly. Before applying, file down the infected areas of nail as much as possible using the nail file provided. Do not use nail files used for infected nails on healthy nails, as this may spread the infection. Use the swabs provided to clean the nail bed. Repeat for each affected nail. Apply the nail lacquer over the entire surface of the nail. Do not apply to the skin around the nail and avoid contact with the eyes, ears, or mucous membranes of the nostrils or mouth. Allow the treated nail to dry for about 3 minutes.
Remove old nail lacquer and file down nails if required, before using Loceryl again. Use Loceryl until the infection has cleared and healthy nails have grown back. This may take 6 months for finger nails up to 12 months for toe nails.
Read the patient information leaflet (PIL) provided to you with your medication or speak to a healthcare professional for further information and medical advice.
What happens if you use too much Loceryl?
If you use more than prescribed, then it can lead to some unpleasant side effects. You should talk to your doctor or reach out to one of our prescribing clinicians, if you have used too much Loceryl and you experience any side effects.
What are the possible side effects of Loceryl?
Side effects of Loceryl include:
- Nail damages
- Nail discolouration
- Brittle nails
- Skin burning sensation
If you experience any serious side effects, you should contact NHS 111.
If you experience a serious allergic reaction with the signs shown below you should contact emergency services on 999.
- Your lips, mouth, throat or tongue suddenly become swollen
- You’re breathing very fast or struggling to breathe (you may become very wheezy or feel like you’re choking or gasping for air)
- Your throat feels tight or you’re struggling to swallow
- Your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet)
- You suddenly become very confused, drowsy or dizzy
- Someone faints and cannot be woken up
Always report adverse effects to the MHRA yellow card reporting system. You can read more about this here How and where do I report side effects of my medication? – NowPatient
Information about using Loceryl at the same time as other medications or herbal supplements
There is not enough evidence to suggest there are any drug interactions between herbal supplements and Loceryl. In any event, you should let your prescribing clinician know if you are taking any herbal supplements.
What do I do if Loceryl does not work for fungal nail infections?
Loceryl needs to be used for over 3 months to see any effect, but may not work in certain instances. Speak to your doctor for alternative treatments if Loceryl does not work for you.
Can Loceryl used for fungal nail infections be used long term?
You may need to use Loceryl for 6 months for finger nails and up to 12 months for toe nail fungal infections.
Is there a herbal Loceryl?
No. Herbal Loceryl does not exist. If you have been marketed such a formulation, it may be fake.
Can women use Loceryl?
Women can use Loceryl for the treatment of fungal nail infections, but not if you are pregnant or breastfeeding.
Should I avoid any particular food or drink when using Loceryl?
You can eat and drink normally when using Loceryl for the treatment of fungal nail infections.
What lifestyle changes can I make to help me with fungal nail infections?
To prevent fungal nail infections:
- Treat athlete’s foot immediately, to avoid it spreading to nails
- Keep your feet clean and dry
- Wear clean socks
- Do not share nail clippers or scissors
Alternatives to Loceryl
Alternatives for the treatment of fungal nail infections include terbinafine.
Sources
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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FAQs
Answers to Popular Questions About Loceryl Nail Lacquer
What is Loceryl Nail Lacquer?
Loceryl Nail Lacquer is a medicated nail polish containing amorolfine 5%, used to treat fungal nail infections (onychomycosis). It is manufactured by Galderma and is available both as a prescription-only medicine and as a pharmacy (P) medicine in the UK. Loceryl is applied directly to the affected nails once or twice weekly and works by penetrating the nail plate to kill the fungi causing the infection. It is suitable for treating mild to moderate fungal nail infections that affect up to two nails and no more than two-thirds of the nail plate.
How does Loceryl Nail Lacquer work?
Amorolfine, the active ingredient in Loceryl, is a morpholine antifungal that works by inhibiting two key enzymes in the fungal cell membrane: delta-14 reductase and delta-7–8 isomerase. This disrupts the production of ergosterol, an essential component of the fungal cell membrane, causing the membrane to become unstable and the fungal cell to die. The lacquer formulation allows amorolfine to penetrate through the nail plate to reach the infection underneath, creating high local concentrations of the drug.
Can I buy Loceryl without a prescription?
Yes, Loceryl Nail Lacquer (marketed as Loceryl Curanail for pharmacy sale) is available without a prescription from pharmacies in the UK. However, the pharmacist will ask questions to ensure it is suitable — they will check how many nails are affected, how much of the nail is involved, and whether the nail matrix (the root) is affected. If the infection is severe or widespread, the pharmacist may advise seeing a GP for a stronger treatment. Loceryl is also available on prescription from your GP or through NowPatient.
How do I apply Loceryl Nail Lacquer?
Apply Loceryl once or twice weekly following these steps: (1) File the affected nail surface with the provided file to roughen and thin the nail, allowing better penetration. (2) Clean the nail surface with the provided swab (alcohol cleanser). (3) Apply the lacquer thinly over the entire affected nail using the spatula provided — do not use the same file or spatula on healthy nails. (4) Allow to dry for approximately 3–5 minutes. (5) Re-seal the bottle tightly. Do not use nail varnish remover between applications; remove old lacquer weekly using the provided swabs.
How long does Loceryl take to work?
Fungal nail treatment with Loceryl requires patience. Fingernail infections typically take 6 months of treatment, while toenail infections may take 9–12 months or longer — this is because nails grow slowly and the treatment must continue until the infected portion of nail has fully grown out. You should see healthy new nail growing from the base over time. Do not stop treatment early even if the nail looks improved, as the fungus may not be completely eliminated and the infection can return.
Can I wear nail varnish while using Loceryl?
It is generally best to avoid cosmetic nail varnish or gel/shellac nails while using Loceryl, as these create a barrier that may reduce the penetration of amorolfine into the nail. If you wish to wear nail varnish, apply it over the Loceryl lacquer once it has fully dried, but remove both layers before the next Loceryl application. Artificial nails (acrylics, gels) should not be used during treatment as they trap moisture and can worsen fungal infections.
What are the side effects of Loceryl?
Side effects from Loceryl Nail Lacquer are uncommon because it is applied topically to the nail with minimal systemic absorption. When side effects do occur, they are usually local and mild, including nail discolouration, brittle or broken nails, and burning sensation at the application site. Rarely, contact dermatitis (skin redness and itching around the nail) may develop. If you experience persistent or severe skin irritation, stop using Loceryl and consult your pharmacist or doctor.
Is Loceryl effective for all nail infections?
Loceryl is most effective for mild to moderate fungal nail infections that affect up to two nails and involve no more than two-thirds of the nail plate. It is less effective for severe infections that involve the nail matrix (root), thick or very discoloured nails, or infections affecting many nails. In these cases, oral antifungal treatment (such as terbinafine tablets) may be more appropriate. Your doctor can take a nail clipping to confirm fungal infection before starting treatment, as not all nail problems are caused by fungi.
How should I store Loceryl?
Store Loceryl Nail Lacquer below 25°C, away from heat and direct sunlight. Keep the bottle tightly closed when not in use — the lacquer can thicken if exposed to air. Do not use Loceryl after the expiry date. Keep all nail files and applicators separate for infected and healthy nails to avoid spreading the infection. Dispose of used files regularly. Keep out of reach of children.
How can I get Loceryl?
Loceryl Curanail is available over the counter from pharmacies without a prescription. For a fuller range of fungal nail treatments, or if the pharmacist recommends seeing a doctor, you can get a prescription from your GP or through NowPatient’s online service. NowPatient can assess whether topical treatment alone is sufficient or whether oral antifungal medication would be more appropriate for your infection.
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