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Buy COLOFAC safely, securely and easily in a few simple steps. Start a consultation today to check your eligibility with a prescribing clinician, at no cost to you.

Includes Free Private Prescription

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Manufactured by Mylan


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Updated on 26 Mar 2024

What to do if you missed your COLOFAC dose

The MHRA's reporting program for suspected side effects to medicines, vaccines, e-cigarettes, medical device incidents, defective or falsified (fake) products to the Medicines and Healthcare products Regulatory Agency to ensure safe and effective use.

Learn more about reporting side effects

About Colofac

Colofac contains mebeverine hydrochloride, an antispasmodic, as the active ingredient. It is used for the treatment of irritable bowel syndrome (IBS). Common symptoms of IBS, include stomach and intestine pain, intense bloating, flatulence, diarrhoea, and constipation. Colofac relaxes stomach muscles, reducing stomach cramps, a common symptom of irritable bowel syndrome.

It is available with a prescription or over the counter under the brand name Colofac. NowPatient offers Colofac as a treatment for IBS only, following an online consultation with a prescribing clinician.

Key facts of Colofac

  • For the treatment of irritable bowel syndrome
  • Colofac can take up to 1 hour to start working
  • Colofac has some side effects which may include a mild itchy skin rash
  • It can be dangerous if you take Colofac with certain medications. If you’re not sure if it is safe, discuss this with the prescribing clinician

Who is Colofac not suitable for?

Colofac may not be suitable for some people. To make sure it’s safe for you, speak to the prescribing clinician before taking Colofac if you:

  • Are allergic to mebeverine or any of the inactive ingredients such as lactose, povidone, talc, magnesium stearate, sucrose, gelatin, acacia or carnauba wax
  • Are over 40 years of age
  • Have new IBS symptoms or your symptoms have gotten worse
  • Have liver or kidney problems
  • Have blood in your stools
  • Are under 18 years of age

How and where to get Colofac?

Colofac is available from a number of sources. It is available on prescription or over the counter at a pharmacy.

NowPatient does not allow customers to buy Colofac directly. Our service is certified, safe and effective, and we only ever treat conditions. If you book a consultation with a prescribing clinician for the treatment of IBS, you can discuss if Colofac is a suitable treatment option for you.

At the end of the consultation, the clinician will decide if a treatment plan is suitable for you. If it is, the clinician will issue you with a prescription which can then be ordered, paid for and delivered directly to your chosen address by NowPatient.

Dosage and strength for Colofac for irritable bowel syndrome

Colofac is available as 135 mg tablets when used for IBS.

Information about how to take Colofac for irritable bowel syndrome

Swallow Colofac tablets whole with a glass of water. For best results, take Colofac around 20 minutes before a meal. Adults should take 1 tablet 3 times a day. Do not take more than 3 Colofac tablets in any 24-hour period.

If you miss a dose take it as soon as you can. If it is almost time for your next dose, skip the missed dose and take it at the next scheduled time.

What happens if you take too much Colofac?

If you take more than prescribed, then it can lead to some unpleasant side effects. You should talk to your doctor or reach out to one of our prescribing clinicians, if you have taken too much Colofac and you experience any of the following side effects.

What are the side effects of Colofac?

Side effects of Colofac include:

  • Mild itchy skin rash

If you experience any serious side effects, you should contact NHS 111.

If you experience a serious allergic reaction with the signs shown below you should contact emergency services on 999.

  • Swelling of the face, neck, tongue, or throat
  • Difficulty breathing (you may become very wheezy or feel like you’re choking or gasping for air)
  • Your throat feels tight or you’re struggling to swallow
  • Your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet)
  • You suddenly become very confused, drowsy or dizzy
  • Someone faints and cannot be woken up

Always report adverse effects to the MHRA yellow card reporting system. You can read more about this here How and where do I report side effects of my medication? – NowPatient

Information about taking Colofac at the same time as other medications or herbal supplements

There is not enough evidence to suggest there are any drug interactions between herbal supplements and Colofac. In any event, you should let your prescribing clinician know if you are taking any herbal supplements.

Can Colofac taken for irritable bowel syndrome be taken long term?

Mebeverine is not recommended for long term use. You should only take mebeverine if you have a flare-up of IBS symptoms.

Is there a herbal Colofac?

No. Herbal Colofac does not exist. If you have been marketed such a formulation, it may be fake.

Can women use Colofac?

Women can take Colofac for IBS. Pregnant women or those breastfeeding however, should speak to a doctor before taking Colofac tablets.

Should I avoid any particular food or drink when taking Colofac?

You can eat and drink normally when taking Colofac tablets.

What lifestyle changes can I make to help me with irritable bowel syndrome?

  • Manage your stress levels
  • Eat a balanced diet
  • Avoid foods that make your IBS worse

Alternatives to Colofac

Alternatives for the treatment of IBS include treatments such as Fybogel mebeverine sachets, Colpermin capsules, or Buscopan.


Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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