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RHEUMATREX

RHEUMATREX

Used for Cancer

Are you tired of high medication costs? Our service offers unbeatable savings on your RHEUMATREX prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.

Manufactured by DAVA Pharmaceuticals

*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.

This content is intended for US audiences only

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Lower the cost of your RHEUMATREX prescription

You can lower cost of your RHEUMATREX using one of the 4 following drug savings programs
  • Qualified

    NowPatient's Rx Advantage card is a simple & convenient way to save money on your RHEUMATREX

    Rx Advantage Card

    Save up to 90%

  • Available

    N/A
    Manufactured by
    N/A
    Powered by
    Buy your RHEUMATREX without insurance from Canada at discounts of up to 90% using NowPatient's Canadian Prescription savings program.

    Canadian Prescription Savings

  • Unavailable

    Obtain your RHEUMATREX for as little as $0 per fill. Suitable for insured individuals only.

    Drug Coupons

    Unavailable
  • Unavailable

    Obtain your RHEUMATREX at no cost. Suitable for insured, underinsured and uninsured individuals

    Patient Assistance Programs

    Unavailable
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RHEUMATREX key facts

What is RHEUMATREX?

What is RHEUMATREX?

RHEUMATREX is the brand name for methotrexate and is available as an oral tablet.

What dosages is RHEUMATREX available in?

What dosages is RHEUMATREX available in?

RHEUMATREX is available as a 2.5 mg oral tablet.

What is RHEUMATREX used for?

What is RHEUMATREX used for?

RHEUMATREX is an antimetabolite that is used to treat:

  • Acute lymphoblastic leukemia (ALL) in adults and children; given with other chemotherapy
  • Cutaneous T-cell lymphoma in adults; given by itself or with other chemotherapy
  • Advanced non-Hodgkin lymphoma in adults; given with other chemotherapy
  • Rheumatoid arthritis (RA) in adults
  • Polyarticular juvenile idiopathic arthritis (pJIA) in children
  • Severe psoriasis in adults
How does RHEUMATREX work?

How does RHEUMATREX work?

RHEUMATREX is an antimetabolite medication that treats many types of cancers and non-cancer conditions (like arthritis and psoriasis). For cancer: TREXALL works by blocking dihydrofolate reductase, a protein in your body that’s important for making DNA in cells and for cell growth. Since cancer cells grow much more quickly than healthy cells, the medication helps slow down cancer growth so the cancer can’t spread as well.

For non-cancer conditions: We don’t know exactly how TREXALL works to treat non-cancer conditions such as rheumatoid arthritis and psoriasis. But research suggests that, at lower doses, it blocks the immune system from becoming too active. For psoriasis, the medication might also help slow down the growth of skin cells.

How do I take RHEUMATREX?

How do I take RHEUMATREX?

The dose of RHEUMATREX varies depending on what condition you’re taking the medication for. Sometimes, the dose depends on your body size or body surface area (BSA) in m2 units. It is typically taken by mouth up to 4 times a week.

Is it safe for me to take RHEUMATREX?

Is it safe for me to take RHEUMATREX?

RHEUMATREX is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you are pregnant or breastfeeding, have alcoholic liver disease, bone marrow hypoplasia, leukopenia, thrombocytopenia or significant anemia.

RHEUMATREX Common Side Effects

RHEUMATREX Common Side Effects

Common side effects of RHEUMATREX:

  • Mouth sores
  • Nausea or vomiting
  • Diarrhea
  • Stomach upset
  • Dizziness
  • Tiredness
  • Chills
  • Fever
  • Infection
  • Higher liver enzyme levels in the blood
  • Low white blood cells
  • Low platelet levels
RHEUMATREX Serious Side Effects

RHEUMATREX Serious Side Effects

Serious side effects are rare with RHEUMATREX. Contact your healthcare provider immediately if you experience any of the following.

  • Serious infections (from having low white blood cell counts): temperature of 100.4 degrees Fahrenheit, with or without other symptoms, such as chills, cough, muscle aches, very fast heartbeat, confusion
  • Low platelets: blood in urine or stool, nosebleeds, unexplained bruising or bleeding, bruising or bleeding that doesn’t go away
  • Serious lung problems: sudden cough, fever, difficulty breathing
  • Serious liver problems: nausea, vomiting, tiredness, stomach pain or swelling, pale-colored stool, dark-colored urine, yellowing of the whites of the eyes or skin
  • Serious nervous system problems: headache, confusion, vision changes, difficulty talking, difficulty moving one side of the body, seizure, coma
  • Serious skin reactions: painful blisters, skin wounds, peeling skin, fever, sore throat, body aches
  • Allergic reaction: rash, difficulty breathing, swelling of the mouth or around the eyes
Effects of other drugs, drug classes and over-the-counter products on RHEUMATREX

Effects of other drugs, drug classes and over-the-counter products on RHEUMATREX

The following medications may interact with RHEUMATREX:

  • Concomitant administration of some NSAIDs with high dose RHEUMATREX therapy has been reported to elevate and prolong serum methotrexate levels, resulting in deaths from severe hematologic and gastrointestinal toxicity
  • RHEUMATREX is partially bound to serum albumin, and toxicity may be increased because of displacement by certain drugs, such as salicylates, phenylbutazone phenytoin, and sulfonamides. Renal tubular transport is also diminished by probenecid; use of RHEUMATREX with this drug should be carefully monitored
  • Oral antibiotics such as tetracycline, chloramphenicol, and nonabsorbable broad spectrum antibiotics, may decrease intestinal absorption of RHEUMATREX or interfere with the enterohepatic circulation by inhibiting bowel flora and suppressing metabolism of the drug by bacteria
  • Penicillins may reduce the renal clearance of RHEUMATREX; increased serum concentrations of RHEUMATREX with concomitant hematologic and gastrointestinal toxicity have been observed with RHEUMATREX. Use of RHEUMATREX with penicillins should be carefully monitored
Who makes RHEUMATREX?

Who makes RHEUMATREX?

DAVA Pharmaceuticals

Is RHEUMATREX safe in pregnancy?

Is RHEUMATREX safe in pregnancy?

RHEUMATREX can cause embryo-fetal toxicity, including fetal death. For non-neoplastic diseases, RHEUMATREX is contraindicated in pregnancy. For neoplastic diseases, advise patients of reproductive potential of the potential risk to a fetus and to use effective contraception.

What is the generic name for RHEUMATREX?

What is the generic name for RHEUMATREX?

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects

Drug Savings Guide

A practical guide to saving money and receiving support with prescription costs

How can NowPatient help me to lower the cost of my RHEUMATREX prescription?

After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your RHEUMATREX prescription

Applicability to each program will be dependent on your insurance status.

How do the NowPatient RHEUMATREX savings programs work?

After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.

Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.

Are the NowPatient RHEUMATREX savings programs suitable for everyone, regardless of insurance status?

No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.

Rx Advantage Card* for RHEUMATREXCanadian Prescription Savings* for RHEUMATREXRHEUMATREX Drug Coupon*RHEUMATREX Patient Assistance Program*
Insured (federal, state or government)AvailableAvailableNot AvailableAvailable If Offered by Pharmaceutical Company
Insured (Commercial or Private)AvailableAvailableAvailable If Offered by Pharmaceutical CompanyAvailable If Offered by Pharmaceutical Company
UninsuredAvailableAvailableNot AvailableAvailable If Offered by Pharmaceutical Company
Insured but without pharmacy benefit or drug coverageAvailableAvailableNot AvailableAvailable If Offered by Pharmaceutical Company

*This is not insurance.

Are the NowPatient drug savings programs suitable for brand and generic versions of RHEUMATREX?

No. Each program has applicability requirements. Please see below

Rx Advantage Card* for RHEUMATREXCanadian Prescription Savings* for RHEUMATREXRHEUMATREX Drug Coupon*RHEUMATREX Patient Assistance Program*
BrandYesYesYes, If Offered by Pharmaceutical CompanyYes, If Offered by Pharmaceutical Company
GenericYesYesNoNo

*This is not insurance.

If you have Medicare Part D or Medicare Advantage and none of the RHEUMATREX savings options are applicable or affordable for me, what can you do?

If you are insured with Medicare and the RHEUMATREX drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.

The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.

People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.

If you are denied Medicaid for RHEUMATREX, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).

I am uninsured or underinsured and none of the RHEUMATREX prescription saving options are applicable or affordable for me, what can I do?

If you are uninsured or underinsured (for example, RHEUMATREX is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.

The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.

If you are denied and all else fails, and if you have been prescribed RHEUMATREX for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.

I am commercially or privately insured and none of the RHEUMATREX prescription saving options are applicable or affordable for me, what can I do?

If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.

If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.

However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.

The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.

If I have federal, state or commercial insurance and none of the RHEUMATREX prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?

If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:

1. Patient Access Network Foundation (PAN) assistance for RHEUMATREX

If you are having trouble paying for your RHEUMATREX medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for RHEUMATREX you will need to meet one or all of the following criteria:

  • Your income is below 400% of the federal poverty level
  • RHEUMATREX is prescribed for an approved FDA indication
  • You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
  • You have Medicare insurance coverage that covers RHEUMATREX
  • If RHEUMATREX is listed on PAN’s list of covered medications

You can check the Patient Access Network Foundation Website for more information.

2. HealthWell Foundation Copay Program for RHEUMATREX

If you are having trouble paying for your RHEUMATREX medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for RHEUMATREX you will need to meet the following criteria:

  • You live in and are being treated in the United States
  • You are insured and your plan covers RHEUMATREX
  • If RHEUMATREX is listed on the HealthWell Foundation’s list of covered medications

You can check the HealthWell Foundation Website for more information.

3. Patient Advocate Foundation Co-Pay Relief Program for RHEUMATREX

Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your RHEUMATREX treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for RHEUMATREX you will need to meet the following criteria:

  • You must be currently insured and have coverage for RHEUMATREX
  • You must have a confirmed diagnosis and treatment plan
  • You must reside and receive treatment in the United States
  • Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
  • Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.

You can check the Patient Advocate Foundation Website for more information.

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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You can lower the cost of your prescription medications using our various savings programs which include drug coupons, savings card and manufacturer-sponsored patient assistance programs.

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