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Is the cost of your methotrexate too expensive?

You may qualify for programs where you can pay as little as $0 per fill, subject to income and insurance status.

This content is intended for US audiences only

NowPatient offers cost effective access to methotrexate for everyone including those who are uninsured, those who have commercial insurance as well as those who are enrolled into state or federal programs like Medicaid, Medicare Part D, full Low Income Subsidy (LIS, “Extra Help”), TRICARE or Veterans (VA) Benefits.

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Table of contents
OverviewWhat can I do if I am commercially insured but cannot afford my methotrexate?What can I do if I am uninsured and cannot afford my methotrexate?What can I do if I am insured with Medicare and cannot afford my methotrexate?Am I eligible for the Rx Advantage Card and how much does methotrexate cost without insurance?What will my out-of-pocket cost be for methotrexate when using the Rx Advantage Card?Is it legal for me to pay cash for methotrexate even though I have insurance?Does the Rx Advantage Card work with Medicare or any other federal or state insurance plans?Does the Rx Advantage Card work with Commercial Insurance?How do I check prices for methotrexate and how do I use the Rx Advantage Card?Do I need to pay for the Rx Advantage Card?Is there a methotrexate co-pay program?Is there a methotrexate Patient Assistance Program (PAP)?What should I do if I take too much methotrexate?What are the benefits of NowPatient?What is generic methotrexate?FDA approval of methotrexateActive ingredient of methotrexateUS brand name of methotrexate and manufacturerUK brand name of methotrexate and manufacturerPrescription requirement for methotrexateAvailability of methotrexate in the UK with NHS prescriptionConditions treated by methotrexateHow does methotrexate work?Forms of methotrexate availableDosage of methotrexateDirections for methotrexate useWarnings and precautions for methotrexateUse of methotrexate during pregnancyUse of methotrexate while breastfeedingInteractions with other drugsPossible side effects of methotrexateSimilar drugs to methotrexateSourcesPeople also asked
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Medically reviewed by Navin Khosla, BPharm and written by Rajive Patel, BPharm - Updated on 25 Jan 2024
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What can I do if I am commercially insured but cannot afford my methotrexate?

If you are commercially insured and you cannot afford your copay or co-insurance you can opt for purchasing methotrexate outside of your plan using the Rx Advantage card, with costs that are usually lower than a typical plan copay. If you elect to use this method, out of pocket costs do not contribute towards your plan deductibles.

If you cannot afford the cash price possibly due to income constraints, then there is the option of applying to state assistance programs like Medicaid. Often, you may be able to receive your methotrexate without any costs at all. You can check Medicaid eligibility in your state by following this link HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application.

What can I do if I am uninsured and cannot afford my methotrexate?

If you cannot afford the cash price of methotrexate using the Rx Advantage card then there is the option of applying to state programs like Medicaid. Often, you may be able to receive your methotrexate without any costs at all. You can check Medicaid eligibility in your state by following this link HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application.

What can I do if I am insured with Medicare and cannot afford my methotrexate?

If you are insured with Medicare and have Part D or an Advantage drug plan but cannot afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you have a number of options:

Option

Savings Information

RX ADVANTAGE CARD

You can use the Rx Advantage to purchase the medication outside of your plan at prices that may be lower than you copay or co-insurance element. If you elect to use this method, out of pocket costs do not contribute towards your plan deductibles.

LOW INCOME SUBSIDY

If this is still too expensive or unaffordable then you can apply for federal support like Low Income Subsidy (LIS). To be eligible for Low Income Subsidy, you need to be resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).

MEDICAID

Alternatively, you can check Medicaid eligibility in your state by following this link to the HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.

Am I eligible for the Rx Advantage Card and how much does methotrexate cost without insurance?

Our website gives savings options to customers who wish to purchase methotrexate, as either a brand or generic, without the constraints of insurance. By using the Rx Advantage Card, users can save up to 90% on the cost of their medication. The card can be used at over 65,000 pharmacies nationwide, across America. Even if you are insured, in most cases the cash price will be significantly cheaper than your existing co-pay. NowPatient is able to negotiate discounts on bulk drug purchases with pharmacy owners meaning you can access lower medication prices at nearby pharmacies using our card that can be conveniently stored in your NowPatient account.

What will my out-of-pocket cost be for methotrexate when using the Rx Advantage Card?

Your out-of-pocket (OOP) cost will effectively be the discounted cash price you pay for methotrexate using the Rx Advantage Card. If you are insured, your OOP expense can not be used against your plan deductible, if your plan has a deductible.

Yes. The Rx Advantage card is especially useful for people who have High-deductible health plans (HDHPs). It can be used for insured, uninsured, and underinsured persons.

Does the Rx Advantage Card work with Medicare or any other federal or state insurance plans?

No. We do not bill any federal or state insurance including Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug benefit). When you purchase your medication using the NowPatient Rx Advantage Card, you will be doing so out of pocket. The spend will not count towards your plan deductibles or gaps in the event you have a plan with a deductible. The out-of-pocket methotrexate cash price you pay can be typically cheaper than your plan copay.

Does the Rx Advantage Card work with Commercial Insurance?

We do not bill your commercial insurance. When you purchase your medication using the Rx Advantage Card, from NowPatient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps in the event you have a plan with a deductible. The out-of-pocket methotrexate cash price you pay can be typically cheaper than your plan copay.

How do I check prices for methotrexate and how do I use the Rx Advantage Card?

You can search for the prices at nearby pharmacies using our website. Simply search your medication and enter your ZIP Code and we will show you the price of your drug at nearby pharmacies. If you are happy with the quote, you need to create an account with NowPatient and generate your card. Next, simply go to the pharmacy and fill your methotrexate Rx. Ask the pharmacy to run the card and check the price, even if they tell you they have another card they use. Your card is stored safely in your NowPatient account.

Do I need to pay for the Rx Advantage Card?

No. The Rx Advantage prescription savings card is FREE to use and store for NowPatient users.

Is there a methotrexate co-pay program?

Generic medications like methotrexate do not have co-pay card savings options. A Copay program, if available, would normally be for the brand name version of methotrexate. You can search the brand name of methotrexate and check to see if a co-pay program exists. Co-pay cards are programs run by pharmaceutical companies that offer you a direct way to lower your out-of-pocket costs for prescription drugs for eligible patients. The copay cards essentially allow physicians to prescribe medications that are clinically preferred.

Is there a methotrexate Patient Assistance Program (PAP)?

Generic medications like methotrexate do not have PAP savings options. A Patient assistance program, if available would normally be for the brand name version of methotrexate. You can search the brand name of methotrexate and check to see if a co-PAP exists. PAPs are programs that are run and sponsored by pharmaceutical companies. They offer uninsured, insured, or underinsured individuals access to high-cost brand-name medications, which may otherwise be unaffordable.

What should I do if I take too much methotrexate?

Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using methotrexate. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you've used too much methotrexate. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.

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What is generic methotrexate?

Generic methotrexate refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of methotrexate

Methotrexate is approved by the U.S. Food and Drug Administration (FDA) for the treatment of various conditions, including rheumatoid arthritis, psoriasis, and certain types of cancer.

Active ingredient of methotrexate

The active ingredient of methotrexate is methotrexate.

US brand name of methotrexate and manufacturer

Methotrexate is available in the US under various brand names, including Rheumatrex and Trexall. It is manufactured by different pharmaceutical companies.

UK brand name of methotrexate and manufacturer

In the UK, methotrexate is available under various brand names, including Maxtrex. The manufacturer may vary depending on the brand name.

Prescription requirement for methotrexate

A prescription (Rx) is required for methotrexate in both the US and the UK.

Availability of methotrexate in the UK with NHS prescription

Methotrexate is available in the UK with an NHS prescription.

Conditions treated by methotrexate

Methotrexate is used to treat a range of conditions, including rheumatoid arthritis, psoriasis, psoriatic arthritis, certain types of cancer (such as leukemia and lymphoma), and ectopic pregnancy.

How does methotrexate work?

Methotrexate is an immunosuppressive medication that works by inhibiting the metabolism of certain cells, including rapidly dividing cells such as cancer cells or cells involved in inflammation. It helps to reduce inflammation and suppress the immune system’s response, providing relief for conditions such as rheumatoid arthritis and psoriasis.

Forms of methotrexate available

Methotrexate is available in various forms, including oral tablets, injectable solutions, and prefilled syringes for subcutaneous administration.

Dosage of methotrexate

The dosage of methotrexate may vary depending on the specific condition being treated and individual factors. It is important to follow the recommended dosage instructions provided by the healthcare provider.

Directions for methotrexate use

Methotrexate should be taken exactly as directed by the healthcare provider. The medication is typically taken once a week for certain conditions. It may be taken orally or administered by injection, depending on the form prescribed.

Warnings and precautions for methotrexate

  • Methotrexate can have serious side effects, including liver toxicity, lung problems, and bone marrow suppression. Regular monitoring of blood counts and liver function is necessary during treatment
  • Tell your doctor if yoiu have liver disease, lung disease (such as pulmonary fibrosis), suppressed immune system, blood cell/bone marrow disorders, peptic ulcer, ulcerative colitis, or any active infections before taking methotrexate
  • It may interact with certain medications and should be used with caution in individuals with certain medical conditions, such as kidney or liver disease. Inform the healthcare provider about all medications being taken and medical history

Use of methotrexate during pregnancy

Methotrexate is contraindicated during pregnancy as it can cause harm to the developing fetus. Effective contraception should be used during methotrexate treatment, and pregnancy should be avoided.

Use of methotrexate while breastfeeding

Methotrexate is generally not recommended while breastfeeding as it can pass into breast milk and may harm the nursing infant. Breastfeeding should be avoided during methotrexate treatment.

Interactions with other drugs

Methotrexate may have drug interactions with certain medications, including live vaccines, nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, sulfasalazine, penicillins, phenytoin, and probenecid. It is important to inform your healthcare provider about all medications, over-the-counter supplements, and herbal products you are taking to avoid potential interactions.

Possible side effects of methotrexate

Common side effects of methotrexate may include nausea, vomiting, drowsiness, mouth sores, sore throat, fatigue, and hair loss. Call a healthcare professional right away if you experience a dry cough, fever, shortness of breath, extreme tiredness, loss of appetite, or yellowing of the skin or eyes. Your doctor will most likely give you folic acid tablets to reduce adverse effects caused by your weekly dose of methotrexate.

Similar drugs to methotrexate

Other medications used for the treatment of conditions such as rheumatoid arthritis and psoriasis include leflunomide, sulfasalazine, and biologic therapies such as adalimumab and etanercept.

Sources

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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