HydralazinePrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Hydralazine
    Generic for Apresoline
    30 tablets $3.9 USD
    Save $2.10
  3. Hydralazine
    Generic for Apresoline
    30 tablets $4.2 USD
    Save $1.80
  4. Hydralazine
    Generic for Apresoline
    30 tablets $4.2 USD
    Save $1.80
  5. Hydralazine
    Generic for Apresoline
    60 tablets $5.7 USD
    Save $6.30
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Do you need a prescription for hydralazine?

Yes, hydralazine is only available with a valid physician Rx.

How much is hydralazine without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase hydralazine, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for hydralazine in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a hydralazine savings card?

Yes. Save up to 90% on your hydralazine with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a hydralazine coupon provider in the US?

No. Now Patient does not provide hydralazine coupons or FREE hydralazine samples.

Do you accept commercial, Medicare or Medicaid coverage for hydralazine in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much hydralazine?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using hydralazine. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much hydralazine. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic hydralazine?

Generic hydralazine refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of hydralazine

Hydralazine is approved by the U.S. Food and Drug Administration (FDA) for the treatment of high blood pressure (hypertension).

Active ingredient of hydralazine

The active ingredient of hydralazine is hydralazine hydrochloride.

US brand names of hydralazine and manufacturers

Hydralazine is available under various brand names in the US, including Apresoline. The medication is manufactured by different pharmaceutical companies.

UK brand names of hydralazine and manufacturers

In the UK, hydralazine is available under various brand names, including Apresoline. The manufacturers may vary depending on the brand name.

Prescription requirement for hydralazine

A prescription (Rx) is required for hydralazine in both the US and the UK.

Availability of hydralazine in the UK with NHS prescription

Hydralazine is available in the UK with an NHS prescription.

Conditions treated by hydralazine

Hydralazine is a medication that belongs to the class of drugs known as vasodilators. It is primarily used for the treatment of high blood pressure (hypertension) when other antihypertensive agents are not effective or not suitable.

In addition to treating hypertension, hydralazine may also be used in the treatment of congestive heart failure. This condition occurs when the heart is unable to pump enough blood to meet the body’s needs. By dilating the blood vessels, hydralazine can reduce the workload on the heart and improve its pumping ability.

Furthermore, hydralazine is sometimes prescribed in combination with other medications to manage certain kidney conditions, such as renal hypertension or renal artery stenosis. These conditions involve the narrowing of blood vessels leading to the kidneys, which can impair their function. By dilating the blood vessels, hydralazine helps to improve blood flow and alleviate symptoms associated with these kidney conditions.

It is important to note that hydralazine should always be used under the guidance and prescription of a healthcare professional. They will determine the appropriate dosage and duration of treatment based on individual needs and medical history.

Mechanism of action

When you take hydralazine, it is absorbed into your bloodstream and reaches the smooth muscle cells that line the walls of your blood vessels. Once there, it acts directly on the muscle cells, causing them to relax. This relaxation leads to the dilation or widening of the blood vessels, which in turn reduces the resistance to blood flow and lowers blood pressure.

Hydralazine primarily affects the arteries, which are the blood vessels that carry oxygen-rich blood away from the heart to the rest of the body. By dilating the arteries, hydralazine allows more blood to flow through them, reducing the pressure on the heart and decreasing the workload it has to perform.

In addition to its vasodilatory effects, hydralazine also has some effects on the heart muscle. It can increase the force of contraction of the heart, helping it pump blood more efficiently. This can be especially beneficial for individuals with heart failure, where the heart is weakened and has difficulty pumping blood effectively.

Forms of hydralazine available

Hydralazine is available in the form of oral tablets and injections for intravenous use.

Dosage of hydralazine

The dosage of hydralazine may vary depending on the specific condition being treated, individual patient factors, and the healthcare provider’s recommendations. It is important to follow the prescribed dosage instructions and drug information provided by the healthcare provider. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Directions for hydralazine use

Hydralazine should be taken exactly as directed by the healthcare provider. The medication may be taken with or without food. It is important to continue taking hydralazine regularly to maintain its effectiveness. Keep hydralazine in its original container at room temperature, away from moisture and heat. Do not store it in the bathroom or in the car, as these environments can be too hot and humid, which can affect the medication’s potency.

Drug interactions

  • Taking hydralazine with other blood pressure medications can result in a significant drop in blood pressure. This can cause symptoms such as dizziness, lightheadedness, or even fainting. It is important to monitor blood pressure closely and adjust medication dosages if necessary
  • Combining hydralazine with nitroglycerin, a medication used to treat chest pain (angina), can cause a severe drop in blood pressure. This combination should be used with caution and under the guidance of a healthcare professional
  • When hydralazine is taken with beta-blockers, which are commonly used to treat high blood pressure and heart conditions, the effects of both medications may be enhanced. This can lead to a further reduction in heart rate and blood pressure. Regular monitoring by a healthcare professional is essential in such cases
  • Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen, can reduce the effectiveness of hydralazine in lowering blood pressure. It is important to use these medications with caution and under the guidance of a healthcare professional
  • Taking hydralazine with monoamine oxidase inhibitors (MAOIs) a class of medications used to treat depression, can lead to a potentially dangerous increase in blood pressure. It is important to avoid this combination unless specifically instructed by a healthcare professional
  • Certain antidepressants and antipsychotic medications can interact with hydralazine and increase the risk of side effects such as low blood pressure (hypotension). It is important to discuss any medications you are taking with your healthcare provider to ensure the safe use of hydralazine

These are just a few examples of medications that can interact with hydralazine. It is important to disclose all medications you are taking, including prescription drugs, over-the-counter medications and herbal supplements, to your healthcare provider before starting hydralazine. They will be able to assess any potential adverse effects and adjust your treatment plan accordingly.

Warnings and precautions for hydralazine

  • Hydralazine should be used with caution in individuals with certain medical conditions, such as heart disease, kidney disease, or systemic lupus erythematosus (SLE)
  • It may interact with certain medications, including other blood pressure medications and medications that affect the liver. Inform the healthcare provider about all medications being taken
  • Before using this medication, tell your doctor or pharmacist your medical history, especially of heart problems (such as coronary artery disease, recent heart attack, rheumatic heart disease of the mitral valve), blood vessel problems, previous stroke and kidney problems

Use of hydralazine during pregnancy

The use of hydralazine during pregnancy should be carefully considered, and the potential risks and benefits should be discussed with a healthcare provider.

Use of hydralazine while breastfeeding

Hydralazine may pass into breast milk, and its use during breastfeeding is generally not recommended. Consultation with a healthcare provider is necessary to assess the potential risks and benefits.

Possible side effects of hydralazine

Common side effects of hydralazine may include headaches, dizziness, flushing, loss of appetite and rapid heartbeat (palpitations). Serious side effects can include allergic reactions, chest pain, and swelling. It is important to report any concerning symptoms to a healthcare provider for medical advice.

Similar drugs to hydralazine

Other medications used for the treatment of high blood pressure (hypertension) include ACE inhibitors, beta-blockers, calcium channel blockers, and diuretics.


  • FDA Prescribing Information for Hydralazine
  • MHRA product information for Hydralazine
  • WebMD – Hydralazine
  • Drugs.com – Hydralazine
  • NHS UK
Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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