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Is the cost of your desmopressin too expensive?

You may qualify for programs where you can pay as little as $0 per fill, subject to income and insurance status.

This content is intended for US audiences only

NowPatient offers cost effective access to desmopressin for everyone including those who are uninsured, those who have commercial insurance as well as those who are enrolled into state or federal programs like Medicaid, Medicare Part D, full Low Income Subsidy (LIS, “Extra Help”), TRICARE or Veterans (VA) Benefits.

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Table of contents
OverviewWhat can I do if I am commercially insured but cannot afford my desmopressin?What can I do if I am uninsured and cannot afford my desmopressin?What can I do if I am insured with Medicare and cannot afford my desmopressin?Am I eligible for the Rx Advantage Card and how much does desmopressin cost without insurance?What will my out-of-pocket cost be for desmopressin when using the Rx Advantage Card?Is it legal for me to pay cash for desmopressin even though I have insurance?Does the Rx Advantage Card work with Medicare or any other federal or state insurance plans?Does the Rx Advantage Card work with Commercial Insurance?How do I check prices for desmopressin and how do I use the Rx Advantage Card?Do I need to pay for the Rx Advantage Card?Is there a desmopressin co-pay program?Is there a desmopressin Patient Assistance Program (PAP)?What should I do if I take too much desmopressin?What are the benefits of NowPatient?What is generic desmopressin?FDA approval of desmopressinActive ingredient of desmopressinUS brand name of desmopressin and manufacturerUK brand name of desmopressin and manufacturerPrescription requirement for desmopressinAvailability of desmopressin in the UK with NHS prescriptionConditions treated by desmopressinHow does desmopressin work?Forms of desmopressin availableDosage of desmopressinDirections for desmopressin useWarnings and precautions for desmopressinDrug interactions with desmopressinUse of desmopressin if pregnant or planning pregnancyPossible side effects of desmopressinSimilar drugs to desmopressinSourcesPeople also asked
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Medically reviewed by Navin Khosla, BPharm and written by Rajive Patel, BPharm - Updated on 25 Jan 2024
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What can I do if I am commercially insured but cannot afford my desmopressin?

If you are commercially insured and you cannot afford your copay or co-insurance you can opt for purchasing desmopressin outside of your plan using the Rx Advantage card, with costs that are usually lower than a typical plan copay. If you elect to use this method, out of pocket costs do not contribute towards your plan deductibles.

If you cannot afford the cash price possibly due to income constraints, then there is the option of applying to state assistance programs like Medicaid. Often, you may be able to receive your desmopressin without any costs at all. You can check Medicaid eligibility in your state by following this link HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application.

What can I do if I am uninsured and cannot afford my desmopressin?

If you cannot afford the cash price of desmopressin using the Rx Advantage card then there is the option of applying to state programs like Medicaid. Often, you may be able to receive your desmopressin without any costs at all. You can check Medicaid eligibility in your state by following this link HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application.

What can I do if I am insured with Medicare and cannot afford my desmopressin?

If you are insured with Medicare and have Part D or an Advantage drug plan but cannot afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you have a number of options:

Option

Savings Information

RX ADVANTAGE CARD

You can use the Rx Advantage to purchase the medication outside of your plan at prices that may be lower than you copay or co-insurance element. If you elect to use this method, out of pocket costs do not contribute towards your plan deductibles.

LOW INCOME SUBSIDY

If this is still too expensive or unaffordable then you can apply for federal support like Low Income Subsidy (LIS). To be eligible for Low Income Subsidy, you need to be resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).

MEDICAID

Alternatively, you can check Medicaid eligibility in your state by following this link to the HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.

Am I eligible for the Rx Advantage Card and how much does desmopressin cost without insurance?

Our website gives savings options to customers who wish to purchase desmopressin, as either a brand or generic, without the constraints of insurance. By using the Rx Advantage Card, users can save up to 90% on the cost of their medication. The card can be used at over 65,000 pharmacies nationwide, across America. Even if you are insured, in most cases the cash price will be significantly cheaper than your existing co-pay. NowPatient is able to negotiate discounts on bulk drug purchases with pharmacy owners meaning you can access lower medication prices at nearby pharmacies using our card that can be conveniently stored in your NowPatient account.

What will my out-of-pocket cost be for desmopressin when using the Rx Advantage Card?

Your out-of-pocket (OOP) cost will effectively be the discounted cash price you pay for desmopressin using the Rx Advantage Card. If you are insured, your OOP expense can not be used against your plan deductible, if your plan has a deductible.

Yes. The Rx Advantage card is especially useful for people who have High-deductible health plans (HDHPs). It can be used for insured, uninsured, and underinsured persons.

Does the Rx Advantage Card work with Medicare or any other federal or state insurance plans?

No. We do not bill any federal or state insurance including Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug benefit). When you purchase your medication using the NowPatient Rx Advantage Card, you will be doing so out of pocket. The spend will not count towards your plan deductibles or gaps in the event you have a plan with a deductible. The out-of-pocket desmopressin cash price you pay can be typically cheaper than your plan copay.

Does the Rx Advantage Card work with Commercial Insurance?

We do not bill your commercial insurance. When you purchase your medication using the Rx Advantage Card, from NowPatient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps in the event you have a plan with a deductible. The out-of-pocket desmopressin cash price you pay can be typically cheaper than your plan copay.

How do I check prices for desmopressin and how do I use the Rx Advantage Card?

You can search for the prices at nearby pharmacies using our website. Simply search your medication and enter your ZIP Code and we will show you the price of your drug at nearby pharmacies. If you are happy with the quote, you need to create an account with NowPatient and generate your card. Next, simply go to the pharmacy and fill your desmopressin Rx. Ask the pharmacy to run the card and check the price, even if they tell you they have another card they use. Your card is stored safely in your NowPatient account.

Do I need to pay for the Rx Advantage Card?

No. The Rx Advantage prescription savings card is FREE to use and store for NowPatient users.

Is there a desmopressin co-pay program?

Generic medications like desmopressin do not have co-pay card savings options. A Copay program, if available, would normally be for the brand name version of desmopressin. You can search the brand name of desmopressin and check to see if a co-pay program exists. Co-pay cards are programs run by pharmaceutical companies that offer you a direct way to lower your out-of-pocket costs for prescription drugs for eligible patients. The copay cards essentially allow physicians to prescribe medications that are clinically preferred.

Is there a desmopressin Patient Assistance Program (PAP)?

Generic medications like desmopressin do not have PAP savings options. A Patient assistance program, if available would normally be for the brand name version of desmopressin. You can search the brand name of desmopressin and check to see if a co-PAP exists. PAPs are programs that are run and sponsored by pharmaceutical companies. They offer uninsured, insured, or underinsured individuals access to high-cost brand-name medications, which may otherwise be unaffordable.

What should I do if I take too much desmopressin?

Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using desmopressin. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you've used too much desmopressin. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.

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What is generic desmopressin?

Generic desmopressin refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of desmopressin

Desmopressin is approved by the U.S. Food and Drug Administration (FDA) for various indications, including the treatment of diabetes insipidus and nocturnal enuresis.

Active ingredient of desmopressin

The active ingredient of desmopressin is desmopressin acetate.

US brand name of desmopressin and manufacturer

Desmopressin is available in the US under various brand names, including DDAVP and Stimate. The manufacturers may vary depending on the brand names.

UK brand name of desmopressin and manufacturer

In the UK, desmopressin is available under various brand names, including Octim, DDAVP®; DesmoMelt; Desmospray; Desmotabs; Noqdirna. The manufacturer may vary depending on the brand name.

Prescription requirement for desmopressin

A prescription (Rx) is required for desmopressin in both the US and the UK.

Availability of desmopressin in the UK with NHS prescription

Desmopressin is available in the UK with an NHS prescription.

Conditions treated by desmopressin

Desmopressin is a medication primarily used for the treatment of certain conditions related to water balance in the body. It is a synthetic version of the hormone vasopressin, which is responsible for regulating the body’s water levels.
One of the main uses of desmopressin is to treat diabetes insipidus, a condition characterized by excessive thirst and urination. Desmopressin helps to reduce the frequent urination and excessive thirst associated with this condition by increasing the reabsorption of water in the kidneys.
Additionally, desmopressin is also used in the treatment of bedwetting (nocturnal enuresis) in children and adults. It helps to reduce the production of urine during sleep, allowing individuals to have a dry night.
Furthermore, desmopressin can be prescribed to manage bleeding disorders, such as hemophilia A and von Willebrand disease. It works by increasing the levels of clotting factor VIII and von Willebrand factor, which are necessary for proper blood clotting.

How does desmopressin work?

Desmopressin works by mimicking the action of vasopressin, which is a hormone produced naturally in the pituitary gland. Vasopressin plays a crucial role in regulating water reabsorption in the kidneys and controlling the concentration of urine.
When desmopressin is administered, it binds to specific receptors in the kidneys called vasopressin V2 receptors. This binding triggers a series of intracellular events that lead to the insertion of water channels, known as aquaporin-2 channels, into the cells of the renal collecting ducts. These channels allow water to be reabsorbed from the urine back into the bloodstream, resulting in a decrease in urine volume and an increase in urine concentration.
By increasing water reabsorption, desmopressin helps to reduce excessive urine production and control the symptoms of conditions such as diabetes insipidus, bedwetting (nocturnal enuresis), and excessive thirst associated with certain medical conditions.

Forms of desmopressin available

Desmopressin is available in various forms, including nasal sprays, tablets, and injectable formulations.

Dosage of desmopressin

The dosage of desmopressin may vary depending on the specific indication and the form of the medication. It is important to follow the recommended dosage instructions provided by the healthcare provider.

Directions for desmopressin use

Desmopressin should be taken or administered as directed by the healthcare provider. The specific instructions may include the timing of administration, dosage adjustments, and any necessary precautions.
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Store desmopressin tablets at room temperature away from moisture, light, and heat.

Warnings and precautions for desmopressin

  • Individuals who have had a previous hypersensitivity or allergic reaction to desmopressin or any of its components should avoid using the medication. Signs of an allergic reaction may include rash, itching, swelling, dizziness, or difficulty breathing
  • Desmopressin works by increasing water reabsorption in the kidneys, which can potentially lead to dilutional hyponatremia, a condition characterized by low sodium levels in the blood. Therefore, desmopressin should be used with caution, or not at all, in patients with pre-existing hyponatremia or conditions that increase the risk of developing hyponatremia (e.g., heart failure, kidney disease)
  • Desmopressin can cause high blood pressure, especially in individuals with poorly controlled hypertension. Therefore, it should be used with caution or avoided in patients with uncontrolled high blood pressure
  • Desmopressin is primarily eliminated by the kidneys, so individuals with severe renal impairment may have a decreased ability to clear the medication from their system. This can increase the risk of side effects and potential toxicity. Dosage adjustments may be necessary for patients with renal impairment
  • Desmopressin is commonly used to treat bleeding disorders such as von Willebrand disease. However, it should be avoided in patients with type 2B von Willebrand disease, as it can potentially worsen bleeding symptoms in this specific subtype
  • Desmopressin should be used with caution in patients at risk of fluid overload, such as those with heart failure or certain kidney disorders. Excessive fluid retention can lead to complications such as edema and exacerbation of underlying conditions
  • It is important to follow the healthcare provider’s instructions regarding fluid intake and restrictions while using desmopressin

Drug interactions with desmopressin

Here are some drug interactions that have been reported with desmopressin:

  • Drugs like amitriptyline and imipramine, which belong to the TCA class, may increase the risk of water retention and hyponatremia (low sodium levels) when used in combination with desmopressin. Close monitoring by your doctor is necessary if you require both medications
  • Certain SSRIs (Selective Serotonin Reuptake Inhibitors) including fluoxetine and sertraline, may increase the risk of hyponatremia when used concomitantly with desmopressin. Hyponatremia is a condition characterized by low levels of sodium in the blood and can be potentially dangerous. Your doctor may need to adjust your medications or monitor your sodium levels closely if you are taking both desmopressin and an SSRI
  • Taking desmopressin in combination with other antidiuretic hormone (ADH) agonists medications such as carbamazepine or chlorpropamide, may increase the risk of water overload and hyponatremia. Your doctor will need to monitor your fluid balance and sodium levels closely if you are taking these medications together
  • Lithium is a medication commonly used to treat bipolar disorder. It can increase the antidiuretic effect of desmopressin, leading to the risk of water retention and hyponatremia. Close monitoring by your doctor is necessary if you are taking both medications

These are just a few examples of drug interactions that can occur with desmopressin. It is important to inform your healthcare professional about all the medications you are taking, including over-the-counter drugs, supplements, and herbal products, to ensure the safe use of desmopressin. They can assess the potential risks and benefits and make any necessary dosage adjustments or recommendations.

Use of desmopressin if pregnant or planning pregnancy

The use of desmopressin during pregnancy should be discussed with a healthcare provider. The potential benefits and risks should be evaluated on an individual basis.

Possible side effects of desmopressin

Common adverse effects of desmopressin may include headache, nausea, abdominal pain, and nasal congestion. Serious side effects are rare but can occur. Promptly report any concerning symptoms to a healthcare provider.

Similar drugs to desmopressin

Other medications, such as vasopressin analogues and antidiuretic hormone analogues, may be used as alternatives to desmopressin for the treatment of diabetes insipidus and related conditions.

Sources

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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