Key facts about Azactidine Tablets
What dosages is Azactidine Tablets available in?
Azactidine Tablets is available as a 200 mg and 300 mg oral tablet.
What is Azactidine Tablets used for?
Azactidine Tablets is an antimetabolite that is used to treat acute myeloid leukemia maintenance treatment in adults.
How does Azactidine Tablets work?
Azactidine Tablets is a chemotherapy medication called a hypomethylating agent. It works by inserting itself in the genetic material of cancer cells. By doing this, it turns on certain genes that help kill cancer cells. As a result, AML cells no longer grow out of control.
How do I take Azactidine Tablets?
Azactidine Tablets is dosed as follows:
- Acute myeloid leukemia
- Each chemotherapy cycle with Azactidine Tablets (azacitidine) lasts about 1 month (28 days)
- Days 1-14: The typical dose is to take 300 mg by mouth daily
- Days 15-28: Don’t take any Azactidine Tablets (azacitidine).
- Repeat chemotherapy cycle
Your dose of Azactidine Tablets might be different if you experience certain side effects.
Is it safe for me to take Azactidine Tablets?
Azactidine Tablets is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Azactidine Tablets Common Side Effects
Common side effects of Azactidine Tablets:
- Low white blood cells
- Nausea
- Low platelets
- Vomiting
- Diarrhea
- Tiredness or weakness
- Constipation
- Fever, cough, and other symptoms of pneumonia
- Low red blood cells
- Stomach pain
Azactidine Tablets Serious Side Effects
Serious side effects are rare with Azactidine Tablets. Contact your healthcare provider immediately if you experience any of the following.
- Serious infections: fever, headache, chills, extreme tiredness, low energy, muscle aches, cough, sore throat, congestion
- Serious bleeding: unusual bruising or bleeding, bleeding that takes longer to stop, bleeding from the nose or gums, black or tarry stool
Effects of other drugs, drug classes and over-the-counter products on Azactidine Tablets
There are no major drug interactions listed for Azactidine Tablets. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes Azactidine Tablets?
Various FDA-approved generic manufacturers
Is Azactidine Tablets safe in pregnancy?
Azactidine Tablets can harm your unborn baby.
Females who are able to become pregnant:
- Your healthcare provider should perform a pregnancy test before you start treatment with Azactidine Tablets.
You should use effective birth control (contraception) during treatment and for at least 6 months after your last dose of Azactidine Tablets. Tell your healthcare provider right away if you become pregnant during treatment with Azactidine Tablets.
Males with a female sexual partner who can become pregnant:
- You should use effective birth control (contraception) during treatment and for at least 3 months after your last
dose of Azactidine Tablets.
