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What is Abilify Mycite system and how does it work?

What is Abilify Mycite system and how does it work?

Amish Patel - NowPatientGreen tick
Created on 14 Mar 2024
Updated on 16 Jul 2024

Abilify Mycite stands at the forefront of technological advances in medication management, combining the antipsychotic drug aripiprazole with a groundbreaking ingestible sensor to track adherence. This innovative digital medicine system manufactured by Otsuka Pharmaceutical Co. aims to transform the treatment landscape for individuals living with mental health conditions such as schizophrenia, bipolar I disorder, and major depressive disorder, particularly when used alongside other antidepressant medications. FDA-approved (U.S. Food and Drug Administration) Abilify Mycite not only offers a therapeutic solution but also digital surveillance of drug intake, marking a new chapter in personalized healthcare.

The introduction of Abilify Mycite raises pivotal considerations regarding patient privacy and safety, addressing potential side effects including increased risks in certain populations. As healthcare providers and patients navigate these dimensions, Abilify Mycite promises to enhance treatment outcomes and support in managing complex conditions like schizophrenia and dementia. This guide sheds light on the intricate workings, benefits, and crucial steps for those beginning their journey with Abilify Mycite.

The science behind Abilify Mycite

Abilify Mycite is a sophisticated prescription medication system designed to track the ingestion of the antipsychotic drug aripiprazole in tablet form. It is specifically approved for use by adults and is intended to assist in the treatment of conditions such as Schizophrenia, Bipolar I Disorder, and Major Depressive Disorder, in combination with other antidepressant medications. The system, however, is not sanctioned for improving patient compliance or altering aripiprazole dosages.

Key components of the Abilify Mycite System:

  • Abilify Mycite Pill: Embedded with a sensor, this pill communicates with an external patch once ingested
  • MYCITE Patch: A non-medicated, wearable patch that detects the signal from the pill via Bluetooth, records the time of ingestion and monitors the patient’s activity and rest patterns
  • MYCITE App: This smartphone app receives data from the patch, providing insights into medication adherence
  • MYCITE Dashboard: A web-based portal system accessible to healthcare providers and support networks, allowing them to view shared data and assist in managing the patient’s treatment plan

The system’s technology involves an ingestible sensor within the Abilify Mycite pill that, upon swallowing, emits a signal received by the MYCITE Patch. This patch, adhered to the patient’s body, not only logs the medication intake but also tracks physical activity and rest, offering a comprehensive overview of the patient’s well-being. Data from the patch is then wirelessly transmitted to the MYCITE App, where it is displayed and stored for the patient’s review. The MYCITE Dashboard serves as a portal for healthcare teams, facilitating informed discussions about mental health and enabling personalized treatment strategies.

While the system’s impact on treatment adherence has not been conclusively demonstrated, it represents a significant step forward in digital health, providing near-real-time information on aripiprazole ingestion. It is important to note that Abilify Mycite carries a Boxed Warning indicating an increased risk of death for elderly patients with dementia-related psychosis and an elevated risk of suicidal thoughts and behaviors in younger populations on antidepressants. Common side effects in adults may include restlessness, dizziness, nausea, and insomnia, among others.

Key components of Abilify Mycite System

The Abilify Mycite System revolutionizes medication adherence and monitoring through its four main components:

  • Abilify Mycite Pill: At the core is the Abilify Mycite pill, an aripiprazole tablet available in various strengths (2 mg to 30 mg) integrated with an Ingestible Event Marker (IEM) sensor. The sensor activates upon ingestion and communicates with the external Mycite Patch
  • MYCITE Patch: This nonmedicated, wearable sensor includes a reusable data pod and a weekly disposable adhesive strip. Resistant to water and sweat, it logs the exact time the medication is taken, measures the patient’s activity levels by counting steps, and monitors rest periods
  • MYCITE App: Patients can access their medication intake data through this smartphone application. It allows for daily check-ins to track mood, sleep quality, energy levels, and physical activity. The app also provides reminders, such as when to replace the disposable adhesive strip on the patch
  • MYCITE Dashboard: An online portal for healthcare providers and the patient’s support network, the dashboard offers a detailed view of the patient’s medication adherence, physiological data, and self-reported mood and rest quality over various time frames (7-day to 90-day views)

In addition to these, the system includes a selection of coping activities in the app to assist with symptom management and detailed instructions for setup and use. The Abilify Mycite Kit contains a month’s supply of the pill, patches, setup instructions, and monthly prescription refills. Importantly, the FDA has evaluated and approved only the drug ingestion tracking functions of the system, and it is not intended for real-time or emergency monitoring. Data reliability may be affected by factors such as poor connection or lack of smartphone access. Despite the bankruptcy of Proteus, the developer of the IEM, the system continues to provide a comprehensive approach to managing mental health conditions.

Benefits for patients and healthcare providers

The Abilify Mycite System confers several benefits to both patients and healthcare providers by enhancing medication adherence and monitoring health data:

  • Enhanced medication adherence: By tracking medication ingestion and health patterns, the system helps patients and healthcare providers identify and understand adherence behaviors. This can lead to more informed discussions about treatment plans and foster proactive management of mental health conditions
  • Informed healthcare conversations: Healthcare providers gain access to medication ingestion data, activity levels, and patient-reported mood and rest quality. This comprehensive overview allows for personalized treatment strategies and strengthens the therapeutic alliance between patients and providers
  • Empowerment and privacy: Patients maintain control over their health data, choosing who to share information with, which empowers them in their treatment journey. The system’s design ensures patient privacy while fostering trust and collaboration within the support network

The system’s capabilities extend to various aspects of patient care:

  • Data-driven decisions: Healthcare providers can remotely access data with patient consent, enabling a better understanding of medication adherence and allowing for adjustments to treatment plans as necessary
  • Trust and consistency: The system provides a single source of information, reducing uncertainty and ensuring that both patients and providers are working with the same data, thereby fostering trust
  • Comprehensive health tracking: Abilify Mycite tracks not only medication ingestion but also activity, rest, mood, energy levels, and coping activities, offering a holistic view of the patient’s well-being

By leveraging these features, the Abilify Mycite System facilitates a more nuanced approach to mental health care, emphasizing the importance of adherence and personalized care.

Privacy and safety considerations

In assessing the privacy and safety considerations of the Abilify Mycite System, it is critical to understand that:

Real-time monitoring limitations:

  • The system is not designed for real-time or emergency monitoring
  • There may be delays in the detection of the tablet, which means it should not be relied upon for immediate or critical updates

Data protection measures:

  • Data security is paramount, with encryption and secure cloud storage safeguarding user privacy
  • Access to patient data is restricted and controlled by the patient, who can determine who views their information and adjust these preferences at any time

Patient privacy and consent:

  • The iDAS MyCite app allows patients to withdraw consent to data sharing, fostering trust and control
  • Healthcare professionals access data with patient consent, using a code entered into the app

Furthermore, the Abilify Mycite System carries specific safety warnings:

Boxed warnings:

  • An increased risk of death is noted for elderly patients with dementia-related psychosis
  • There is a heightened risk of suicidal thoughts and behaviors in children, adolescents, and young adults

Side effects and contraindications:

  • In clinical trials, the most common side effects include restlessness, dizziness, nausea, and insomnia
  • Known hypersensitivity to aripiprazole is a contraindication for use

Lastly, it is essential to consider the system’s implications on the therapeutic relationship:

Potential impact on therapeutic relationship:

  • The benefits of the technology may not be realized without proper training and adherence to best practice guidelines
  • Inadequate or inappropriate use could harm the patient-provider relationship, emphasizing the need for clear guidelines and training

By addressing these considerations, the Abilify Mycite System can be integrated into patient care with an informed approach, balancing innovation with the utmost respect for patient privacy and safety.

How to get started with Abilify Mycite

Initiating treatment with the Abilify Mycite System involves understanding the associated costs and accessing support resources. Here is a breakdown of the financial considerations and technical support available to patients:

Financial aspects:

  • Health insurance impact: The cost of the ABILIFY MYCITE® Kit varies depending on the patient’s health insurance coverage. Patients need to consult with their insurance providers to ascertain the exact costs
  • Commercial insurance programs: Patients with commercial insurance plans may be eligible for an instant copay program, potentially reducing their monthly expense to as little as $5 for the ABILIFY MYCITE Kit
  • Medicaid coverage: The majority of Medicaid plans provide coverage for the ABILIFY MYCITE Kit, subject to prior authorization from the state’s Medicaid program
  • Medicare and LIS: For those under Medicare who qualify for the Low Income Subsidy (LIS), the copays for brand-name medications like ABILIFY MYCITE can be $9.85 per month or less

Technical support:

The Mycite Team is dedicated to assisting patients with any technical issues related to the Abilify Mycite System. They offer a range of support services, including:

  • App navigation assistance: Patients can receive help with navigating and utilizing the MYCITE App to its full potential
  • Troubleshooting: The team is equipped to resolve any technical difficulties that may arise during the use of the system
  • Contact information: Support is available from Monday to Friday, 8 AM to 8 PM Eastern Time, at the toll-free number 844-MYCITE-4 (844-692-4834)

Patients are encouraged to take advantage of these resources to ensure a smooth transition to using the Abilify Mycite System and to optimize their treatment experience.


The Abilify Mycite System represents a paradigm shift in managing mental health, combining medication with technology to empower patients and inform healthcare providers. Its ability to monitor adherence and provide actionable data promises to enhance the quality of care for individuals with conditions like schizophrenia and major depressive disorder. By offering a transparent and collaborative approach to treatment, the system not only prioritizes patient well-being but also signals a new horizon in personalized healthcare.


Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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