Prazosin Generic

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  1. Medication
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  2. Prazosin HCl
    Generic for Minipress
    30 capsules $6.9 USD
    Save $14.10
  3. Prazosin HCl
    Generic for Minipress
    45 capsules $8.1 USD
    Save $23.40
  4. Prazosin HCl
    Generic for Minipress
    60 capsules $10.8 USD
    Save $31.20
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Do you need a prescription for prazosin?

Yes, prazosin is only available with a valid physician Rx.

How much is prazosin without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase prazosin, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for prazosin in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a prazosin savings card?

Yes. Save up to 90% on your prazosin with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a prazosin coupon provider in the US?

No. Now Patient does not provide prazosin coupons or FREE prazosin samples.

Do you accept commercial, Medicare or Medicaid coverage for prazosin in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much prazosin?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using prazosin. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much prazosin. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

US brand name of prazosin and manufacturer

Prazosin is available in the US under the brand name Minipress. It is manufactured by various pharmaceutical companies, including Pfizer.

UK brand name of prazosin and manufacturer

Prazosin hydrochloride is available as a generic in the UK.  It is manufactured by a number of generics manufacturers.

Prescription requirement for prazosin

Prazosin is a prescription medication in both the US and the UK. It is not available over the counter and requires a prescription from a healthcare provider.

FDA approval of prazosin

Prazosin has received FDA approval for the treatment of high blood pressure (hypertension).

Is prazosin available in the UK on NHS?

Prazosin is available on the NHS in the UK. It can be prescribed by healthcare providers for the treatment of high blood pressure and other conditions.

Mechanism of action

Prazosin belongs to a class of medications called alpha-1 blockers. It works by relaxing the smooth muscles in the blood vessels, allowing them to widen. This results in a decrease in blood pressure and improved blood flow.

Uses of prazosin

High blood pressure can cause damage to the heart, blood vessels, and other parts of your body. Damage can cause cardiovascular heart disease, heart failure, heart attacks, stroke, kidney failure, and loss of vision.

Prazosin is an antihypertensive treatment, primarily used for the treatment of high blood pressure (hypertension). It may also be prescribed for other conditions, including benign prostatic hyperplasia (enlarged prostate) and post-traumatic stress disorder (PTSD) related nightmares.

Dosage of prazosin

The dosage of prazosin will vary depending on the individual patient’s condition, response to treatment, and other factors. It is important to follow the dosage instructions provided by your healthcare provider.

Prazosin may cause first-dose hypotension, it is recommended to take your first dose at night. Also, if you forget to take a dose, take it as soon as you can. If it is almost time for your next dose, skip the missed dose and take your next dose at the usual time.

Contraindications and warnings for prazosin

  • Prazosin should not be used in individuals who have a known allergy to the medication or any of its components
  • It is important to inform your healthcare provider about any existing medical conditions, especially low blood pressure, liver disease, or kidney disease
  • Prazosin may cause dizziness or fainting, especially during the initial stages of treatment or when standing up quickly. It is important to rise slowly from a sitting or lying position to minimize these effects
  • Prazosin may interact with certain medications, including other blood pressure medications, erectile dysfunction medications, and certain antidepressants. It is important to inform your healthcare provider about all the medications you are taking to avoid potential interactions
  • Prazosin may cause a decrease in blood pressure, which may result in symptoms such as lightheadedness or dizziness. Regular monitoring of blood pressure may be recommended
  • It is important to avoid activities that require mental alertness or physical coordination until you know how prazosin affects you, as it may cause drowsiness or dizziness

Side effects of prazosin

In clinical trials common side effects of prazosin may include dizziness, drowsiness, headache, and fluid retention. It may also rarely cause more serious side effects, such as low blood pressure, chest pain, an irregular heart rate, palpitations, or allergic reactions (rash, itching, swelling of the face, tongue, or throat, trouble breathing). It is important to discuss any persistent or severe adverse effects with a healthcare professional.

Interactions with other drugs

Prazosin may have drug interactions with other medications, including:

  • Other blood pressure medications
  • Erectile dysfunction medications (e.g., sildenafil, tadalafil)
  • Certain antidepressants (e.g., fluoxetine, paroxetine)
  • Alpha blockers such as doxazosin, and terazosin
  • Beta blockers such as atenolol and propranolol
  • Treatments for erectile dysfunction such as sildenafil, or tadalafil

It is important to inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter drugs, and herbal supplements, to avoid potential interactions.

Is it safe to take prazosin if I am pregnant or planning on becoming pregnant?

Prazosin should be used with caution during pregnancy. It may be prescribed in certain situations, but only if the potential benefits outweigh the potential risks. It is important to discuss the risks and benefits with your healthcare provider.

Is prazosin safe to use while breastfeeding?

Prazosin may pass into breast milk and could potentially affect the nursing infant. It is important to consult with your healthcare provider before using prazosin while breastfeeding to assess the potential risks and benefits.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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