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Manufactured by Ani Pharmaceuticals

*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.

This content is intended for US audiences only

LITHOBID cost saving options available to you

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LITHOBID Uses, Side Effects, Interactions, Warnings & Dosing



LITHOBID is the brand name for lithium carbonate and is available as an extended-release tablet.

What dosages is LITHOBID available in?

What dosages is LITHOBID available in?

LITHOBID is available as a 300 mg extended-release tablet.

What is LITHOBID used for?

What is LITHOBID used for?

LITHOBID is a mood stablizer that is used in the treatment of manic episodes of bipolar disorder or the long-term maintenance treatment of bipolar disorder.

How does LITHOBID work?

How does LITHOBID work?

LITHOBID is a mood stabilizer. It’s not known exactly how lithium works, but it’s thought to affect the levels of certain chemicals in the brain that regulate mood.

How do I take LITHOBID?

How do I take LITHOBID?

The typical dose of LITHOBID is 900 mg by mouth 2 times a day, or 600 mg 3 times a day. The total daily dose is 1,800 mg.
For long-term control: The typical dose is 600 mg by mouth 2 times a day. The total daily dose is 1,200 mg. Your provider will adjust your lithium dose based on if you have kidney problems, how well your bipolar symptoms are responding to the medication, if you’re having side effects, and your blood lithium level.

Is it safe for me to take LITHOBID?

Is it safe for me to take LITHOBID?

LITHOBID is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

LITHOBID Common Side Effects

LITHOBID Common Side Effects

Common side effects of LITHOBID:

  • Hand trembling
  • Excessive urination
  • More thirst
  • Nausea
  • General discomfort when you start treatment
  • Tremor
  • Muscle twitches
  • Restlessness
  • Vomiting
  • Diarrhea
LITHOBID Serious Side Effects

LITHOBID Serious Side Effects

Serious side effects are rare with LITHOBID. Contact your healthcare provider immediately if you experience any of the following.

  • Serotonin syndrome: fast heart rate, dizziness, sweating, flushing, tremor (shakiness), muscle stiffness, muscle twitching or spasms, uncoordinated movement, distress, seizures, hallucinations, coma
  • Lithium toxicity: trouble breathing, seizures, coma, kidney failure, abnormal heart rhythm, dizziness, confusion, blurry vision, poor balance, poor speech, poor coordination
  • Kidney damage: more frequent urination, swelling in legs, fatigue
  • High pressure in the brain and swelling in the eye: severe headaches behind eyes, ringing in the ears, blurred or double vision, and blindness
  • Low blood sodium levels: nausea, fatigue, headache, confusion, disoriented, hallucinations (seeing things that aren’t real), seizures, unconsciousness
  • High blood calcium levels: fatigue, muscle weakness, loss of appetite, nausea, vomiting, constipation, bone pain, depression, confusion
  • Brugada syndrome (life-threatening heart rhythm problem): abnormal ECG findings, unexplained fainting, and irregular heartbeat (palpitations)
Effects of other drugs, drug classes and over-the-counter products on LITHOBID

Effects of other drugs, drug classes and over-the-counter products on LITHOBID

The following medications may interact with LITHOBID:

  • Diuretic-, ACE-, and ARB-induced sodium loss may increase serum LITHOBID concentrations. Start with
  • lower doses of lithium or reduce dosage, while frequently monitoring serum lithium concentrations and
  • signs of lithium toxicity
  • Concomitant administration of LITHOBID with serotonergic drugs can precipitate serotonin syndrome. Monitor patients for signs and symptoms of serotonin syndrome, particularly during lithium initiation. Examples of serotonergic drugs include selective serotonin reuptake inhibitors (SSRI), serotonin and norepinephrine reuptake inhibitors (SNRI), and monoamine oxidase inhibitors (MAOI)
  • Concomitant administration of methyldopa, phenytoin, or carbamazepine with LITHOBID may increase the risk of adverse reactions with these drugs

The following drugs can lower serum LITHOBID concentrations: acetazolamide, urea, xanthine preparations, and alkalinizing agents such as sodium bicarbonate.

  • Concomitant extended use of iodide preparations, especially potassium iodide, with LITHOBID may produce hypothyroidism
  • Concurrent use of calcium channel blocking agents with LITHOBID may increase the risk of neurotoxicity in the form of ataxia, tremors, nausea, vomiting, diarrhea, and/or tinnitus
  • Concurrent use with metronidazole may provoke LITHOBID toxicity. Patients receiving such combined therapy should be monitored closely
  • Concurrent use of fluoxetine with LITHOBID has resulted in both increased and decreased serum LITHOBID concentrations. Patients receiving such combined therapy should be monitored closely

Nonsteroidal anti-inflammatory drugs (NSAIDs): LITHOBID levels should be closely monitored when

  • patients initiate or discontinue NSAID use
Who makes LITHOBID?

Who makes LITHOBID?

Ani Pharmaceuticals

Is LITHOBID safe in pregnancy?

Is LITHOBID safe in pregnancy?

LITHOBID may cause fetal harm when administered to a pregnant woman. You should talk to your healthcare provider before taking this medication if you are pregnant.


What to do if you missed your LITHOBID dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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