HydroxyzinePrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Hydroxyzine HCl
    Generic for Atarax
    60 tablets $6.3 USD
    Save $24.30
  3. Hydroxyzine HCl
    Generic for Atarax
    30 tablets $4.8 USD
    Save $10.50
  4. Hydroxyzine HCl
    Generic for Atarax
    30 tablets $5.1 USD
    Save $10.20
  5. Hydroxyzine Pamoate
    Generic for Vistaril
    30 capsules $5.1 USD
    Save $9.30
  6. Hydroxyzine Pamoate
    Generic for Vistaril
    60 capsules $6 USD
    Save $22.80
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Do you need a prescription for hydroxyzine?

Yes, hydroxyzine is only available with a valid physician Rx.

How much is hydroxyzine without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase hydroxyzine, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for hydroxyzine in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a hydroxyzine savings card?

Yes. Save up to 90% on your hydroxyzine with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a hydroxyzine coupon provider in the US?

No. Now Patient does not provide hydroxyzine coupons or FREE hydroxyzine samples.

Do you accept commercial, Medicare or Medicaid coverage for hydroxyzine in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much hydroxyzine?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using hydroxyzine. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much hydroxyzine. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic hydroxyzine?

Generic hydroxyzine refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of hydroxyzine

Hydroxyzine is approved by the U.S. Food and Drug Administration (FDA) for the treatment of anxiety, itching, and other conditions.

Active ingredient of hydroxyzine

The active ingredient of hydroxyzine is hydroxyzine hydrochloride.

US brand name of hydroxyzine and manufacturer

Hydroxyzine is available in the US under various brand names, including Vistaril and Atarax. It is manufactured by different pharmaceutical companies.

UK brand name of hydroxyzine and manufacturer

In the UK, hydroxyzine is available under various brand names, including Atarax. The manufacturer may vary depending on the brand name.

Prescription requirement for hydroxyzine

A prescription (Rx) is required for hydroxyzine in both the US and the UK.

Availability of hydroxyzine in the UK with NHS prescription

Hydroxyzine is available in the UK with an NHS prescription.

Conditions treated by hydroxyzine

Hydroxyzine is used for the treatment of anxiety, tension, and pruritus (itching). It can also be used as a sedative, an antihistamine, and for the prevention and control of nausea and vomiting.

One of the main uses of hydroxyzine is to alleviate symptoms of anxiety and tension. It helps to calm the mind and reduce feelings of restlessness, making it an effective treatment for individuals with anxiety disorders. It can also be prescribed to help manage symptoms of alcohol withdrawal.

In addition to its anxiolytic properties, hydroxyzine is commonly used to relieve allergic reactions such as itching, hives (urticaria) and skin rashes. It acts by blocking the release of histamine, a substance that triggers allergic reactions in the body. By reducing the release of histamine, hydroxyzine can help alleviate these symptoms and provide relief to individuals suffering from allergies.

Furthermore, hydroxyzine can be prescribed as a sedative to treat insomnia, a sleep disorder characterized by difficulty falling asleep or staying asleep. By promoting relaxation and drowsiness, hydroxyzine can aid in initiating and maintaining sleep, allowing individuals to experience a restful night.

How does hydroxyzine work?

Hydroxyzine is an antihistamine that works by blocking the action of histamine, a substance in the body that causes allergic reactions. By blocking histamine, hydroxyzine helps to relieve symptoms such as itching, redness, and swelling. It also has sedative properties that can help with anxiety and promote relaxation.

Forms of hydroxyzine available

Hydroxyzine is available in various forms, including oral tablets, capsules, and oral solutions.

Dosage of hydroxyzine

The dosage of hydroxyzine may vary depending on the individual’s condition, medical history, and response to the medication. It is important to follow the recommended dosage instructions provided by the healthcare provider. If you miss a dose of hydroxyzine take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up for the missed dose.

Directions for hydroxyzine use

Hydroxyzine should be taken exactly as directed by the healthcare provider. The medication is usually taken orally, with or without food. It is important to swallow the tablets or capsules whole and avoid crushing or chewing them. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Warnings and precautions for hydroxyzine

  • Use caution when driving or operating machinery, as hydroxyzine may cause drowsiness or impair coordination
  • Hydroxyzine is very similar to cetirizine and levocetirizine. Do not use these medications while using hydroxyzine
  • Allergic reactions to hydroxyzine can range from mild skin reactions to severe symptoms like trouble breathing, swelling of the face, lips, or throat, and anaphylaxis. It is essential to consult with a healthcare professional if you have a history of hypersensitivity to any medications before using hydroxyzine
  • Hydroxyzine can potentially prolong the QT interval, which is the time taken for the heart to recharge between beats. If an individual has a history of QT prolongation a condition that affects the heart’s electrical activity, the use of hydroxyzine may increase the risk of developing a potentially life-threatening irregular heart rhythm. Patients with this condition or family history should avoid hydroxyzine or use it with extreme caution under the close supervision of a healthcare professional
  • Use with caution in people with a history of low blood levels of potassium or magnesium
  • Hydroxyzine can cause an increase in intraocular pressure and worsen the symptoms of glaucoma, a condition characterized by increased pressure within the eye. Individuals with glaucoma should exercise caution when using hydroxyzine and discuss the risks and benefits with their eye specialist
  • Hydroxyzine has anticholinergic effects, which means it can interfere with normal bladder function and potentially cause urinary retention. Individuals with a history of urinary retention or bladder outlet obstruction should use hydroxyzine with caution and under the guidance of a healthcare professional

Drug interactions

Some medications that may interact with hydroxyzine include:

  • Central nervous system (CNS) depressants: Hydroxyzine has sedative properties, and combining it with other medications that have similar effects, such as opioids, benzodiazepines, or barbiturates, may increase drowsiness and impair mental alertness
  • Anticholinergic medications: Hydroxyzine has anticholinergic effects, meaning it can interfere with certain nerve signals in the body. Taking hydroxyzine alongside medications that also have anticholinergic properties, like some antidepressants, antihistamines, or muscle relaxants, may increase the risk of side effects such as dry mouth, blurred vision, constipation, and urinary retention
  • QT-prolonging medications: Some medications can prolong the QT interval in the heart’s electrical activity, potentially leading to a life-threatening heart rhythm known as torsades de pointes. Hydroxyzine has the potential to prolong the QT interval as well. Therefore, taking hydroxyzine with other medications that can also prolong the QT interval, such as certain antibiotics, antipsychotics, and antiarrhythmics, may increase the risk of developing this serious heart condition
  • Combining hydroxyzine with monoamine oxidase inhibitors (MAOIs), which are a type of antidepressant medication, can increase the risk of serotonin syndrome. Serotonin syndrome is a potentially life-threatening condition characterized by symptoms such as confusion, agitation, rapid heartbeat, high blood pressure, dilated pupils, and muscle stiffness

It is crucial to inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter drugs, herbal supplements, and vitamins, to ensure that they can assess any potential interactions with hydroxyzine. They can then make appropriate adjustments to your medication regimen to minimize the risk of adverse effects and provide medical advice.

Use of hydroxyzine during pregnancy and breastfeeding

The use of hydroxyzine during pregnancy and breastfeeding should be carefully considered, and the potential risks and benefits should be discussed with a healthcare provider. Hydroxyzine should only be used if the potential benefits outweigh the potential risks.

Possible side effects of hydroxyzine

Common side effects of hydroxyzine may include drowsiness, dry mouth, dizziness, and blurred vision. Serious side effects are possible but less common. Promptly report any concerning symptoms to a healthcare provider to seek medical attention immediately.

Similar drugs to hydroxyzine

Other antihistamine medications used for the treatment of allergies, itching, and anxiety include cetirizine, loratadine, and diphenhydramine.


Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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