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Navin Khosla NowPatientGreen tick
Updated on 24 Apr 2024

caplacizumab-yhdp Uses, Side Effects, Interactions, Warnings & Dosing

What dosages is caplacizumab-yhdp available in?

What dosages is caplacizumab-yhdp available in?

caplacizumab-yhdp is available as an 11 mg single-dose vial.

What is caplacizumab-yhdp used for?

What is caplacizumab-yhdp used for?

caplacizumab-yhdp is an anti-von Willebrand Factor that is used to treat:
Acquired thrombotic thrombocytopenic purpura (aTTP), in combination with plasma exchange and immunosuppressants (medications that lower your immune system)

How does caplacizumab-yhdp work?

How does caplacizumab-yhdp work?

caplacizumab-yhdp treats aTTP by sticking to von Willebrand factor (vWF) in your blood. This prevents your platelets from clumping together to form clots and also keeps your platelet level in the rest of your body from dropping too low.

How do I take caplacizumab-yhdp?

How do I take caplacizumab-yhdp?

You typically start treatment of caplacizumab-yhdp when you start your plasma exchange. Your first dose of caplacizumab-yhdp is injected into the veins by a healthcare provider. After this, your doses of caplacizumab-yhdp can be injected under the skin by a provider, yourself, or your caregiver.

1st day of treatment: The typical dose is 11 mg of caplacizumab-yhdp injected into the veins (IV) at least 15 minutes before plasma exchange by a healthcare provider. Another 11 mg of caplacizumab-yhdp is injected under the skin after your plasma exchange.

Treatment during daily plasma exchange: The typical dose is 11 mg of caplacizumab-yhdp injected under the skin daily after plasma exchange.

Treatment after the last day of plasma exchange: The typical dose is 11 mg injected under the skin daily for about 1 month. Your provider might have you continue taking caplacizumab-yhdp for up to about another month, depending on how you’re responding to the medication.

Is it safe for me to take caplacizumab-yhdp?

Is it safe for me to take caplacizumab-yhdp?

caplacizumab-yhdp is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

caplacizumab-yhdp Common Side Effects

caplacizumab-yhdp Common Side Effects

  • Common side effects of caplacizumab-yhdp:
  • Nosebleeds
  • Headache
  • Bleeding gums
  • Feeling tired
  • Rash and hives
  • Fever
  • “Pins and needles” feeling
  • Difficulty breathing
  • Back pain
  • Muscle pain
  • Urinary tract infection
  • Bleeding at injection or catheter site
caplacizumab-yhdp Serious Side Effects

caplacizumab-yhdp Serious Side Effects

Serious side effects are rare with caplacizumab-yhdp. Contact your healthcare provider immediately if you experience any of the following.

Severe bleeding: fast heart rate, dizziness, light-headedness, pale skin, blood in urine or stool, vomiting or couging up blood

Effects of other drugs, drug classes and over-the-counter products on caplacizumab-yhdp

Effects of other drugs, drug classes and over-the-counter products on caplacizumab-yhdp

  • Concomitant use of anticoagulants or antiplatelet agents with caplacizumab-yhdp may increase
  • the risk of bleeding. Monitor closely for bleeding with concomitant use.
Who makes caplacizumab-yhdp?

Who makes caplacizumab-yhdp?

Various FDA-approved generic manufacturers

Is caplacizumab-yhdp safe in pregnancy?

Is caplacizumab-yhdp safe in pregnancy?

caplacizumab-yhdp may increase the risk of bleeding in the fetus and neonate. Monitor neonates for
All patients receiving caplacizumab-yhdp, including pregnant women, are at risk for bleeding.
Pregnant women receiving caplacizumab-yhdp should be carefully monitored for evidence of
excessive bleeding.


What to do if you missed your caplacizumab-yhdp dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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