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MEDICAL INFORMATION
Almotriptan Key Facts
Other Related Names or Treatments
Axert, Almogran
About Almotriptan
Almotriptan is classed as a selective serotonin receptor agonist, or triptan. It is thought to work by reversing the widening of blood vessels in the brain, helping to ease the symptoms of migraine. Almotriptan is most effective when used at the start of a migraine attack.
Almotriptan is available with a prescription only. NowPatient offers Almotriptan as a treatment for migraines only, following an online consultation with a prescribing clinician.
Key facts of Almotriptan
- For the treatment of migraine attacks
- Almotriptan has some common side effects which include drowsiness and nausea
- It can be dangerous if you take Almotriptan with certain medications. If you’re not sure if it is safe, discuss this with the prescribing clinician
Who is Almotriptan not suitable for?
Almotriptan may not be suitable for some people. To make sure it’s safe for you, speak to the prescribing clinician before taking Almotriptan if you:
- Have ever had an allergic reaction to Almotriptan malate
- Have heart problems such as chest pain, heart attack, stroke, high blood pressure, or heart disease
- Have liver disease or kidney disease
- Have a history of epilepsy
- Have hemiplegic or basilar migraines
- Are taking monoamine oxidase inhibitor (MAOI) antidepressants
- Are taking other triptan medicines
- Are taking ergot-type medications such as dihydroergotamine or ergotamine, or its derivatives, methysergide
- Are taking selective serotonin reuptake inhibitors (SSRI) such as eletriptan, serotonin noradrenaline reuptake inhibitor (SNRI) antidepressants, or St. John’s wort
How and where to get Almotriptan?
You can buy Almotriptan safely and securely from NowPatient. You can start a consultation today for free and if you qualify for treatment, you only pay for the cost of the medication. Delivery is made to your home or office from our registered pharmacy.
Our service is certified, safe and effective, and we only ever treat conditions. If you book a consultation with a prescribing clinician for the treatment of migraines, you can discuss if Almotriptan is a suitable treatment option for you.
At the end of the consultation, the clinician will decide if a treatment plan is suitable for you. If it is, the clinician will issue you with a prescription which can then be ordered, paid for and delivered directly to your chosen address by NowPatient.
Dosage and strength for Almotriptan for migraines
Almotriptan is available as 12.5mg tablets when used for migraine attacks.
Information about how to take Almotriptan for migraines
The recommended dose of Almotriptan is 12.5 mg at the first sign of a migraine headache. If your headache returns, a second dose may be taken after 2 hours, but do not take more than 25 mg within a 24-hour period. If you’re first dose gives no pain relief, do not take a second dose without speaking to your doctor first.
You are advised to read the patient information leaflet supplied with your medication or speak to a healthcare professional for medical advice.
What happens if you take too much Almotriptan?
If you take more than prescribed, then it can lead to some unpleasant side effects. You should talk to your doctor or reach out to one of our prescribing clinicians, if you have taken too much Almotriptan and you experience any of the following side effects:
What are the side effects of Almotriptan?
Side effects of Almotriptan are split into common and serious.
Common side effects include:
- Drowsiness
- Chest pain
- Dry mouth
- Nausea
- Dizziness
If you experience any serious side effects, you should contact NHS 111.
If you experience a serious allergic reaction with the signs shown below you should contact emergency services on 999.
- Your lips, mouth, throat or tongue suddenly become swollen
- You’re breathing very fast or struggling to breathe (you may become very wheezy or feel like you’re choking or gasping for air)
- Your throat feels tight or you’re struggling to swallow
- Your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet)
- You suddenly become very confused, drowsy or dizzy
- Someone faints and cannot be woken up
Always report adverse effects to the MHRA yellow card reporting system. You can read more about this here How and where do I report side effects of my medication? – NowPatient
Information about taking Almotriptan at the same time as other medications or herbal supplements
There is not enough evidence to suggest there are any drug interactions between herbal supplements and Almotriptan. In any event, you should let your prescribing clinician know if you are taking any herbal supplements.
Can Almotriptan taken for migraines be taken long term?
You should not use Almotriptan too often. Speak to your doctor if your migraine does not go away, or if you have migraines or cluster headaches on a regular basis.
Is there a herbal Almotriptan?
No. Herbal Almotriptan does not exist. If you have been marketed such a formulation, it may be fake.
Can women use Almotriptan?
Women can take Almotriptan for the treatment of migraine attacks. It is not known if Almotriptan passes into breast milk. Speak to your doctor if you are breastfeeding or suspect you are pregnant, before taking Almotriptan.
Should I avoid any particular food or drink when taking Almotriptan?
You can eat and drink normally when taking Almotriptan, but you should avoid alcohol during a migraine attack.
What lifestyle changes can I make to help me with migraines?
- Maintain regular sleep patterns
- Exercise
- Eat regular healthy meals
- Reduce your stress
- Avoiding triggers
Alternatives to Almotriptan
Alternatives for the treatment of migraines include other triptans such as frovatriptan, zolmitriptan, rizatriptan, naratriptan and sumatriptan, or painkillers such as paracetamol, aspirin, or ibuprofen.
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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FAQs
Answers to Popular Questions About Almotriptan
What is Almotriptan?
Almotriptan is a triptan medication used for the acute treatment of migraine attacks with or without aura in adults. It is a selective serotonin (5-HT1B/1D) receptor agonist that relieves migraine headache, nausea, and sensitivity to light and sound. Almotriptan is available as 12.5 mg tablets and is a prescription-only medicine in the UK. It is one of seven triptans available in the UK and is known for its good tolerability profile and rapid onset of action.
How does Almotriptan work?
Almotriptan works by stimulating serotonin 5-HT1B/1D receptors in the blood vessels of the brain. During a migraine, cranial blood vessels dilate and become inflamed. Almotriptan causes vasoconstriction (narrowing) of these dilated blood vessels, reduces the release of inflammatory neuropeptides (such as CGRP), and inhibits pain transmission in the trigeminal nerve system. This addresses the underlying pathology of migraine rather than simply masking the pain.
How is Almotriptan different from other triptans?
Almotriptan is one of the better-tolerated triptans with a side effect profile closest to placebo in clinical trials. It has a rapid onset of action (within 30–60 minutes) and good 2-hour headache relief rates (approximately 60–70%). Compared to sumatriptan (the most prescribed triptan), almotriptan may cause fewer chest symptoms and overall side effects. Each triptan has a slightly different pharmacological profile, and if one triptan does not work, another may be effective.
How do I take Almotriptan?
Take one Almotriptan 12.5 mg tablet as soon as a migraine headache begins, with water. If the migraine returns after initial relief, a second dose may be taken, but not sooner than 2 hours after the first dose. The maximum dose in 24 hours is 25 mg (2 tablets). Almotriptan can be taken with or without food. It is intended for the acute treatment of migraine attacks only — do not take it to try to prevent migraines. If the first dose provides no relief at all, do not take a second dose for the same attack.
Should I take Almotriptan during the aura?
It is generally recommended to take triptans during the headache phase of a migraine rather than during the aura phase. Taking a triptan during the aura may be less effective and the headache may still develop. Wait until the headache begins, then take Almotriptan as early as possible for best results. Some patients find it helpful to take a simple analgesic during the aura and reserve the triptan for the headache phase.
What are the side effects of Almotriptan?
Almotriptan is one of the best-tolerated triptans. Common side effects include dizziness, drowsiness, nausea, and fatigue. Triptan sensations such as tingling, warmth, heaviness, tightness or pressure in the chest, throat, or limbs are possible but less common than with some other triptans. These symptoms are usually mild and transient. If chest tightness is severe or persistent, seek medical attention to exclude cardiac causes.
Who should not take Almotriptan?
Almotriptan should not be taken by people with ischaemic heart disease, coronary artery vasospasm (Prinzmetal’s angina), peripheral vascular disease, a history of stroke or TIA, uncontrolled hypertension, or severe hepatic impairment. It should not be used within 24 hours of another triptan or an ergotamine preparation. It should not be used concurrently with MAO inhibitors. Triptans are not recommended for hemiplegic or basilar migraine.
Can I take Almotriptan with other painkillers?
Yes, almotriptan can be taken alongside simple analgesics such as paracetamol, ibuprofen, or aspirin. Combining a triptan with an NSAID can improve response rates. Almotriptan should not be taken with other triptans or ergotamine-containing medications within 24 hours. Avoid excessive use of almotriptan (more than 10 days per month) to prevent medication-overuse headache.
How can I get Almotriptan?
Almotriptan requires a prescription from your GP, neurologist, or online prescriber such as NowPatient. Your prescriber will confirm your diagnosis of migraine and assess your cardiovascular risk. NowPatient offers convenient online consultations for migraine sufferers.
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