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MEDICAL INFORMATION
Relpax Key Facts
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About Relpax
Relpax contains the active ingredient eletriptan hydrobromide and is indicated in adults for the acute treatment of the headache phase of migraine attacks, with or without aura. Eletriptan reduces the symptoms associated with migraines such as headache, nausea and sensitivity to light.
Relpax is a prescription-only medication and may be recommended when other treatments have not been effective or are not well tolerated.
NowPatient offers Relpax as a treatment for migraine following an online consultation with a prescriber.
Key facts of Relpax
- For the treatment of the headache phase of migraine attacks, with or without aura
- Relpax has some common side effects which include nausea, drowsiness and lethargy
- It can interact with potent CYP3A4 inhibitors such as ketoconazole, itraconazole, erythromycin or clarithromycin and ergot-type medications. If you’re not sure if it is safe to use with other treatments, discuss this with the prescribing clinician
Who is Relpax suitable for?
Relpax is suitable for adult patients, 18-65 years of age
Who is Relpax not suitable for?
Relpax may not be suitable for some people. To make sure it’s safe for you, speak to the NowPatient prescribing clinician before using Relpax if you:
- Have a history of heart disease
- Have angina
- Have circulation problems
- Have bowel disease
Do not take Relpax if your migraine differs from those you normally experience.
How and where to get Relpax?
You can buy Relpax safely and securely from NowPatient. You can start a consultation today for free and if you qualify for treatment, you only pay for the cost of the medication. Delivery is made to your home or office from our registered pharmacy.
Our service is certified, safe and effective, and we only ever treat conditions. If you book a consultation with a prescribing clinician for the treatment of migraine, you can discuss if Relpax is a suitable treatment option for you.
At the end of the consultation, the clinician will decide if a treatment plan is suitable for you. If it is, the clinician will issue you with a prescription which can then be ordered, paid for and delivered directly to your chosen address by NowPatient.
Dosage and strength for Relpax for migraine
Relpax is available as 20 mg and 40 mg film-coated tablets.
The typical initial dose is 40 mg, as directed by your prescribing clinician.
What happens if you use too much Relpax?
Using more than the prescribed amount of Relpax will not improve your migraine faster and can increase the risk of side effects, such as hypertension or other more serious cardiovascular symptoms. If you have taken too much and experience side effects, speak to your doctor or reach out to one of our prescribing clinicians.
What are the side effects of Relpax?
Side effects of Relpax are split into common and more serious.
Common side effects include:
- Nausea
- Drowsiness
- Lethargy
More serious side effects include:
- Chest pain or tightness
- Difficulty swallowing
- Some tightness in the throat
- Dizziness
- Nosebleeds
- Sweating
- Abdominal or stomach pain
- Confusion
If you experience any serious side effects, you should contact NHS 111.
If you experience a serious allergic reaction with the signs shown below, you should contact emergency services on 999:
- Your lips, mouth, throat or tongue suddenly become swollen
- You’re breathing very fast or struggling to breathe (you may become very wheezy or feel like you’re choking or gasping for air)
- Your throat feels tight or you’re struggling to swallow
- Your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet)
- You suddenly become very confused, drowsy or dizzy
- Someone faints and cannot be woken up
Always report adverse effects to the MHRA Yellow Card reporting system. You can read more about this here: How and where do I report side effects of my medication?
Information about using Relpax with other medications
Using Relpax alongside other treatments such as potent CYP3A4 inhibitors e.g., ketoconazole, itraconazole, erythromycin, clarithromycin, josamycin and protease inhibitors (ritonavir, indinavir and nelfinavir) is not recommended. Let your prescribing clinician know if you are using any other medications.
Why might Relpax not work for migraine?
Relpax may not work for migraine due variations in individual response to the medication, when Relpax was given and potential drug interactions. Additionally, over time, some people may experience a change in effectiveness, which may require a change in treatment or dosage.
Can Relpax be used lo ng term?
It is not known if Relpax is safe to use for more than three migraine episodes per month. Speak to your doctor if you are experiencing more than three migraine episodes per month. Long-term use should always be monitored by a healthcare professional.
How to store Relpax
- Keep Relpax out of the sight and reach of children
- Do not use this medicine after the expiry date shown on the carton (marked as “EXP”). The expiry date refers to the last day of that month
- No special storage conditions are required for this medicine
- Do not dispose of unused Relpax tablets in wastewater or household waste. Ask your pharmacist how to properly dispose of medicines you no longer use. These steps help protect the environment
Is there a herbal Relpax?
No. Herbal Relpax does not exist. If you have been marketed such a product, it may be counterfeit or unsafe.
Should I avoid any particular food or drink when using Relpax?
You can eat and drink normally while using Relpax. However, it’s important to avoid grapefruit juice as it can affect how the body processes this medication.
What lifestyle changes can I make to help with migraine?
Getting regular sleep and meals, staying hydrated, exercise and managing stress can all help to manage migraines. Identify triggers such as alcohol and caffeine to avoid them.
Alternatives to Relpax
Alternatives for the treatment of migraine include Imigran, Maxalt and Zomig. Your prescriber will help decide which option is most suitable for you.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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FAQs
Answers to Popular Questions About Relpax
What is Relpax?
Relpax is a brand name for eletriptan hydrobromide, a selective serotonin 5-HT1B/1D receptor agonist (triptan) used for the acute treatment of migraine attacks with or without aura. It is available as 20 mg and 40 mg film-coated tablets. Relpax is a prescription-only medicine manufactured by Pfizer. Eletriptan is one of the more potent triptans available, with high 2-hour response rates and good sustained pain-free response.
How does Relpax work?
Like other triptans, Relpax works by stimulating serotonin 5-HT1B/1D receptors on intracranial blood vessels and trigeminal nerve endings. This causes vasoconstriction of dilated cranial arteries, inhibits the release of pro-inflammatory neuropeptides (including CGRP), and blocks pain signal transmission in the trigeminal pathway. Eletriptan has high selectivity for cranial blood vessels and good CNS penetration, which may contribute to its robust efficacy.
How do I take Relpax?
Take one Relpax 40 mg tablet as soon as migraine headache begins, with water. If the headache improves but recurs, a second 40 mg dose may be taken after at least 2 hours. The maximum dose is 80 mg in 24 hours. A lower starting dose of 20 mg is available. Take with or without food. If the first dose provides no relief at all, do not take a second dose for the same attack.
What are the side effects of Relpax?
Common side effects include dizziness, drowsiness, headache (non-migraine), nausea, weakness, and triptan sensations (tingling, warmth, tightness or pressure in the chest, throat, or limbs). These are generally mild and transient. If chest tightness is severe or persistent, seek medical attention. Eletriptan may cause slightly more chest sensation than some other triptans, but this is rarely clinically significant.
Who should not take Relpax?
Relpax is contraindicated in patients with ischaemic heart disease, coronary vasospasm, peripheral vascular disease, history of stroke or TIA, uncontrolled hypertension, severe hepatic impairment, and those taking potent CYP3A4 inhibitors (ketoconazole, itraconazole, clarithromycin, ritonavir). It should not be used within 24 hours of another triptan or ergotamine.
How can I get Relpax?
Relpax requires a prescription from your GP, neurologist, or online prescriber such as NowPatient. It is available on the NHS. Generic eletriptan is also available. Your prescriber will confirm your migraine diagnosis and assess cardiovascular risk before prescribing.
Experienced a Side Effect?
Report to Yellow Card (UK) or MedWatch (US)
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