Treatment options

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Navin Khosla NowPatientGreen tick
Updated on 4 Apr 2024

What to do if you missed your PREBLACON dose

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Other known brand names

Detrusitol, Mariosea XL, Blerone XL, Tolthen XL, Neditol XL, Detrol LA

About Preblacon XL

Preblacon XL contains tolterodine tartrate, an antimuscarinic (anticholinergic), as its active ingredient. It helps to reduce bladder muscle spasms and the urge to frequently urinate, caused by these spasms. Preblacon XL is used to treat the symptoms of an overactive bladder, such as:

  • Urinary urgency (a sudden and urgent need to pee)
  • Urinary frequency (needing to pee more often than usual)
  • Urinary incontinence (wetting yourself)

Tolterodine relaxes muscles around your bladder, allowing your bladder to hold more liquid, stopping you from needing to pee as often or as urgently. It is available with a prescription as generic tolterodine or under brand names such as Preblacon XL, Blerone XL, Tolthen XL, Detrusitol, and Neditol XL.

NowPatient offers generic tolterodine or the branded treatments for urinary incontinence only, following an online consultation with a prescribing clinician.

Key facts of Preblacon XL

  • For the treatment of urinary incontinence
  • Preblacon XL starts to work within 3 to 8 hours but full effects may take up to 4 weeks to be seen
  • Possible side effects of Preblacon XL include dry mouth or headache
  • It can be dangerous if you take Preblacon XL with certain medications. If you’re not sure if it is safe, discuss this with the prescribing clinician
  • You will normally take Preblacon XL slow-release capsules once daily

Who is Preblacon XL suitable for?

Tolterodine may be taken by adults. It may also be given to children 2 years of age and over, on specialist advice.

Who is Preblacon XL not suitable for?

Preblacon XL may not be suitable for some people. To make sure it’s safe for you, speak to the prescribing clinician before taking Preblacon XL if you:

  • Have had an allergic reaction to the active ingredient tolterodine
  • Have urinary retention
  • Have gastric retention
  • Have renal impairment
  • Have myasthenia gravis
  • Have uncontrolled narrow-angle glaucoma
  • Have a severe stomach or bowel condition
  • Have toxic megacolon or ulcerative colitis
  • Have any heart problems such as heart failure, long QT syndrome, or an irregular or slow heart rate (bradycardia)
  • Have heartburn or acid reflux
  • Have a hiatus hernia
  • Have any nerve damage affecting blood pressure, heart rate, peeing and digestion (autonomic neuropathy)
  • Are pregnant, trying to get pregnant or breastfeeding

How and where to get Preblacon XL?

Preblacon XL is available, only with a prescription. It is not available over the counter at a pharmacy.

NowPatient does not allow customers to buy Preblacon XL directly. Our service is certified, safe and effective, and we only ever treat conditions. If you book a consultation with a prescribing clinician for the treatment of urinary incontinence, you can discuss if Preblacon XL is a suitable treatment option for you.

At the end of the consultation, the clinician will decide if a treatment plan is suitable for you. If it is, the clinician will issue you with a prescription which can then be ordered, paid for and delivered directly to your chosen address by NowPatient.

Dosage and strength for Preblacon XL for urinary incontinence

Tolterodine is available as immediate release tablets, but is only available as Preblacon XL 4 mg prolonged-release capsules when used for urinary incontinence.

Information about how to take Preblacon XL for urinary incontinence

Preblacon XL extended release capsules should be taken whole with a glass of water, with or without food, at the same time each day. Do not chew, crush or break open the capsules.

If you are taking the extended-release capsules you will normally take 4mg once a day, unless you have liver or kidney problems, in which case you will take 2mg tablets once a day. For further information please speak to a healthcare professional for medical advice or read the patient information leaflet provided (PIL) with your medication.

What happens if you take too much Preblacon XL?

If you take more than prescribed, then it can lead to some unpleasant side effects. You should talk to your doctor or reach out to one of our prescribing clinicians, if you have taken too much Preblacon XL and you experience any of the following side effects:

What are the side effects of Preblacon XL?

Side effects of Preblacon XL are split into common and serious.

Common side effects include:

  • Dry mouth
  • Dry eyes
  • Dry skin
  • Headache
  • Dizziness, drowsiness, blurred vision
  • Gastrointestinal side effects such as diarrhoea, constipation, vomiting, burping, or passing wind, abdominal pain
  • Palpitations

Serious side effects include:

  • Faecal impaction
  • Urinary retention
  • Urinary tract infection (UTI)
  • Swollen ankles or legs
  • Angioedema – swollen face, throat or tongue, difficulty swallowing or breathing
  • Disorientation

If you experience any serious side effects, you should contact NHS 111.

If you experience a serious allergic reaction with the signs shown below you should contact emergency services on 999.

  • Your lips, mouth, throat or tongue suddenly become swollen
  • You’re breathing very fast or struggling to breathe (you may become very wheezy or feel like you’re choking or gasping for air)
  • Chest pain
  • Your throat feels tight or you’re struggling to swallow
  • Your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet)
  • You suddenly become very confused, drowsy or dizzy
  • Someone faints and cannot be woken up

Information about taking Preblacon XL at the same time as other medications or herbal supplements

There may be drug interactions when using herbal remedies and supplements when taking Preblacon XL. In any event, you should let your prescribing clinician know if you are taking any herbal supplements or other medicinal products, such as:

  • Erythromycin or clarithromycin
  • Ketoconazole or itraconazole
  • Metoclopramide or cisapride
  • Medication for irregular heartbeats such as amiodarone, sotalol, quinidine or procainamide
  • Cyclosporine
  • Vinblastine
  • Can Preblacon XL taken for urinary incontinence be taken long term?

You should not take Preblacon XL longer than you need to. Your doctor will check that you still need to take Preblacon XL every 6 to 12 months.

Is there a herbal Preblacon XL?

No. Herbal Preblacon XL does not exist. If you have been marketed such a formulation, it may be fake.

Can women use Preblacon XL?

Women can take Preblacon XL, but it is not recommended in pregnancy or when breastfeeding. Speak to your doctor about taking Preblacon XL if you’re pregnant, trying to get pregnant, or when breastfeeding.

Should I avoid any particular food or drink when taking Preblacon XL?

You can eat and drink normally when taking Preblacon XL. Some drinks may however irritate your bladder, making your symptoms worse. These include:

  • Coffee, tea, cola and energy drinks
  • Fizzy drinks
  • Alcohol
  • Diet drinks or those with artificial sweeteners
  • Citrus, orange, grapefruit or lime juice

What lifestyle changes can I make to help me with urinary incontinence?

Modifying your lifestyle may have a positive impact on your urinary incontinence and quality of life. These may include:

  • Pelvic floor muscle training to improve your bladder control
  • Stay well hydrated to maintain a healthy urinary function
  • Avoid caffeine, alcohol, and spicy foods
  • Urinate when you feel the urge to
  • When urinating, wait once you have finished for a few moments, and then try again to make sure the bladder is emptied completely

Alternatives to Preblacon XL

Alternatives for the treatment of urinary incontinence include Betmiga, Yentreve and Emselex.


Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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