glyburide
Used for Type 2 Diabetes
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Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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glyburide Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is glyburide available in?
glyburide is available as a 1.25 mg, 2.5 mg and 5 mg oral tablet.
What is glyburide used for?
glyburide is a sulfonylurea and is used to treat type 2 diabetes.
How does glyburide work?
glyburide is in a class of medications known as sulfonylureas. Sulfonylureas work by telling your pancreas to release insulin, which lowers your blood sugar.
How do I take glyburide?
glyburide is typically dosed as 2.5 mg to 5 mg by mouth once daily with breakfast or the first main meal. Your provider will work with you to adjust your dose weekly until your blood sugar level is the target range. The typical maintenance dose ranges from 1.25 mg to 20 mg by mouth, either once daily or divided into smaller doses and taken twice daily.
Is it safe for me to take glyburide?
glyburide is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a hypersensitivity to the drug or type 1 diabetes mellitus, diabetic ketoacidosis, with or without coma or are taking bosentan.
glyburide Common Side Effects
Common side effects of glyburide include:
- Feeling bloated
- Nausea
- Heartburn
glyburide Serious Side Effects
Serious side effects are rare with glyburide. Contact your healthcare provider immediately if you experience any of the following.
- Severe low blood sugar: anxiety, sweating, shaking, confusion, dizziness, weakness, fast heartbeat, feeling hungry, seizures
Effects of other drugs, drug classes and over-the-counter products on glyburide
- The hypoglycemic action of sulfonylureas may be potentiated by certain drugs including nonsteroidal anti-inflammatory agents, ACE inhibitors, disopyramide, fluoxetine, clarithromycin, and other drugs that are highly protein bound, salicylates, sulfonamides, chloramphenicol, probenecid, monoamine oxidase inhibitors, and beta adrenergic blocking agents
- A possible interaction between glyburide and fluoroquinolone antibiotics has been reported resulting in a potentiation of the hypoglycemic action of glyburide
- Rifampin may worsen glucose control of glyburide because rifampin can significantly induce metabolic isozymes of glyburide such as CYP2C9 and 3A4
Who makes glyburide?
Various FDA-approved generic manufacturers
Is glyburide safe in pregnancy?
glyburide hasn’t been well-studied in human pregnancy, so it’s not known whether this medication will cause harm to unborn babies. But there have been reports of babies experiencing seriously low blood sugar levels during delivery. If you’re pregnant or thinking about becoming pregnant, talk with your provider about what medication options are best for you.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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