FluoxetinePrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Fluoxetine
    Generic for Prozac
    30 capsules $4.2 USD
    Save $17.70
  3. Fluoxetine
    Generic for Prozac
    30 capsules $4.2 USD
    Save $17.70
  4. Fluoxetine
    Generic for Prozac
    40 mg
    60 capsules $5.7 USD
    Save $38.10
  5. Fluoxetine
    Generic for Prozac
    60 tablets $6.9 USD
    Save $36.90
  6. Fluoxetine
    Generic for Prozac
    90 milliliterss $9.6 USD
    Save $56.10
  7. Fluoxetine
    Generic for Prozac
    30 tablets $4.2 USD
    Save $17.70
  8. Fluoxetine
    Generic for Prozac
    30 tablets $3.9 USD
    Save $18.00
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Do you need a prescription for fluoxetine?

Yes, fluoxetine is only available with a valid physician Rx.

How much is fluoxetine without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase fluoxetine, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for fluoxetine in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a fluoxetine savings card?

Yes. Save up to 90% on your fluoxetine with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a fluoxetine coupon provider in the US?

No. Now Patient does not provide fluoxetine coupons or FREE fluoxetine samples.

Do you accept commercial, Medicare or Medicaid coverage for fluoxetine in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much fluoxetine?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using fluoxetine. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much fluoxetine. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

US brand name of fluoxetine and manufacturer

Fluoxetine is available in the US under the brand name Prozac. It is manufactured by Eli Lilly and Company.

UK brand name of fluoxetine and manufacturer

Fluoxetine is available in the UK under various brand names, including Prozac; although Prozac has recently been discontinued in the UK. However, it is available as a generic.

Is fluoxetine available in the UK on the NHS?

Yes, fluoxetine is available in the UK on the NHS as a prescription medication.

Prescription requirement for fluoxetine

Fluoxetine is a prescription medication and requires a prescription from a healthcare provider.

Active ingredient of fluoxetine and mechanism of action

The active ingredient in fluoxetine is fluoxetine hydrochloride. It belongs to a class of medications known as selective serotonin reuptake inhibitors (SSRIs).

Fluoxetine is an antidepressant that works by increasing serotonin levels in the brain, which helps regulate mood and emotions. As a selective serotonin reuptake inhibitor (SSRI), it prevents the reabsorption of serotonin into nerve cells, ensuring that more of this neurotransmitter remains available in the brain.

Uses of fluoxetine

Fluoxetine is primarily used for the treatment of depression (also known as major depressive disorder), panic disorder (panic attacks), obsessive-compulsive disorder (OCD), bulimia nervosa (an eating disorder), and premenstrual dysphoric disorder (PMDD). It may also be prescribed off-label for other conditions, such as generalized anxiety disorder and social anxiety disorder.

Forms of fluoxetine

Fluoxetine is available in various forms, including oral capsules and oral liquid. The specific form and strength will depend on the prescribed dosage and formulation.

Dosage of fluoxetine

The dosage of fluoxetine will vary depending on the specific condition being treated, individual patient factors, and response to therapy. It is important to follow the dosage instructions provided by your healthcare provider. The medication is usually taken once daily in the morning or as directed.

If you miss a dose of fluoxetine, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Precautions and warnings for fluoxetine

  • Fluoxetine should be used with caution in patients with a history of seizures, bipolar disorder, or liver or kidney problems
  • Monitor any new or worsening symptoms of mental health such as mood or behavior changes, anxiety, panic attacks, or suicidal thoughts, particularly in adolescents and young adults
  • It may take several weeks for the full therapeutic effects of fluoxetine to be noticeable. Continue taking the medication as prescribed even if you do not immediately feel better
  • Abruptly stopping fluoxetine can cause withdrawal symptoms. Consult your healthcare provider for guidance on discontinuing the medication
  • Exercise caution when consuming alcohol while taking fluoxetine as it can exacerbate side effects and decrease the effectiveness of the medication
  • Fluoxetine may cause a glaucoma attack. If you have closed-angle glaucoma, talk with your doctor before taking this drug
  • Be aware of potential allergic reactions, drug interactions, and contraindications when combining fluoxetine with other medications
  • If you are pregnant, plan to become pregnant, or are breastfeeding inform your healthcare provider. Caution is advised with breastfeeding since fluoxetine does pass into breast milk

Regular monitoring and follow-up with your healthcare provider are important during fluoxetine therapy.

Side effects of fluoxetine

Common side effects of fluoxetine may include:

  • Nausea
  • Headache
  • Insomnia
  • Drowsiness
  • Nervousness or anxiety
  • Dry mouth

Fluoxetine can also cause rare but serious side effects: allergic reactions (difficulty breathing, swelling of your face or throat, itching skin lumps, rashes, hives or blotches on your skin), and a rare condition called serotonin syndrome. Contact your healthcare provider if you experience any severe or persistent side effects.

Drug interactions 

Certain medications can interact with fluoxetine and may cause adverse effects or reduce its effectiveness. Some examples of medications that may interact with fluoxetine include:

  • Monoamine oxidase inhibitors (MAOIs) such as isocarboxazid, linezolid, phenelzine and tranylcypromine
  • Tricyclic antidepressants such as amitriptyline
  • Blood thinners such as warfarin
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen
  • Antipsychotics such as olanzapine, pimozide and thioridazine
  • Certain migraine medications such as sumatriptan
  • Amphetamines
  • St. John’s Wort
  • Narcotic pain medicine such as tramadol

A healthcare professional will be able to evaluate your specific situation, take into account any existing medical conditions you may have, and assess potential drug interactions before determining if it is safe to combine fluoxetine with other medications.

It is important to disclose all medications you are currently taking, including prescription drugs, over-the-counter medications, herbal supplements, and vitamins, to your healthcare provider to ensure they can make an informed decision regarding your treatment plan.

Similar drugs to fluoxetine

Sertraline, citalopram, and paroxetine are all similar drugs to fluoxetine that belong to the class of selective serotonin reuptake inhibitors (SSRIs). Like fluoxetine, they work by increasing the levels of serotonin in the brain to improve mood and relieve symptoms of depression and anxiety. However, each drug has its own unique characteristics and potential side effects, so it’s important to consult with a healthcare professional for personalized advice before starting any medication.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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