PROZAC
Used for Depression
NowPatient helps you obtain your PROZAC prescription for free or at low-cost. Drug savings programs are suitable for individuals who are insured, don't have insurance or are underinsured and can't afford your medicine.
Manufactured by Eli Lilly & Company
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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PROZAC key facts
What is PROZAC?
PROZAC is the brand name for fluoxetine and is available as an oral tablet, capsule, and solution.
What dosages is PROZAC available in?
PROZAC is available as a 10 mg, 20 mg, 40 mg oral capsule, a 10 mg, 20 mg, 60 mg oral tablet, and a 20 mg/5 ml oral solution.
What is PROZAC used for?
PROZAC is an SSRI that is used to treat:
Major depressive disorder (MDD)
Obsessive-compulsive disorder (OCD)
Bulimia
Panic disorder
Depression from bipolar 1 disorder
Treatment resistant depression
How does PROZAC work?
PROZAC is a selective serotonin reuptake inhibitor (SSRI). It works mainly by raising the levels of serotonin, a chemical in your brain. Serotonin plays an important role in regulating your mood and emotions.
How do I take PROZAC?
PROZAC is typically taken starting at 10 mg to 20 mg by mouth once daily. The maximum recommended dose is up to 80 mg daily total.
Is it safe for me to take PROZAC?
PROZAC is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
Serotonin Syndrome and MAOIs: Do not use MAOIs intended to treat psychiatric disorders with PROZAC or within 5 weeks of stopping treatment with PROZAC. Do not use PROZAC within 14 days of stopping an MAOI intended to treat psychiatric disorders. In addition, do not start PROZAC in a patient who is being treated with linezolid or intravenous methylene blue.
Pimozide: Do not use. Risk of QT prolongation and drug interaction.
Thioridazine: Do not use. Risk of QT interval prolongation and elevated thioridazine plasma levels. Do not use thioridazine within 5 weeks of discontinuing PROZAC. Do not use thioridazine within 5 weeks of discontinuing PROZAC.
When using PROZAC and olanzapine in combination, also referto the Contraindications section of the package insert for Symbyax.
PROZAC Common Side Effects
- Common side effects of PROZAC:
- Difficulty falling asleep
- Nausea
- Headache
- Weakness
- Diarrhea
- Low appetite
- Drowsiness
- Anxiety
- Nervousness
- Tremor
- Dry mouth
- Throat pain
- Yawning
- Low sex drive
PROZAC Serious Side Effects
Serious side effects are rare with PROZAC. Contact your healthcare provider immediately if you experience any of the following.
Suicidal thoughts or behaviors
Serotonin syndrome: fast heart rate, dizziness, sweating, flushing, tremor (shakiness), muscle stiffness, muscle twitching or spasms, uncoordinated movement, distress, seizures, distress, hallucinations, coma
Seizures
Allergic reactions: hives, rash, blisters, swelling of the lips or tongue, difficulty breathing
Abnormal heart rhythm (QT prolongation): chest pounding, short of breath, chest pain, feeling faint or lightheaded
Severe bleeding: bruising that doesn’t improve, black-colored stools, pink or red-colored urine, coughing up or vomiting blood, or unusual bleeding from the nose or gums
Low blood sodium levels: nausea, fatigue, headache, confusion, disoriented, hallucinations (seeing things that aren’t real), seizures, unconsciousness
Effects of other drugs, drug classes and over-the-counter products on PROZAC
The following medications may interact with PROZAC:
- Monoamine Oxidase Inhibitors (MAOIs)
- Drugs Metabolized by CYP2D6: Fluoxetine is a potent inhibitor of CYP2D6 enzyme pathway.
- Tricyclic Antidepressants (TCAs): Monitor TCA levels during coadministration with PROZAC or when PROZAC has been
- recently discontinued.
- CNS Acting Drugs: Caution should be used when taken in combination with other centrally acting drugs.
- Benzodiazepines: Diazepam – increased t½, alprazolam – further psychomotor performance decrement due to increased levels.
- Antipsychotics: Potential for elevation of haloperidol and clozapine levels.
- Anticonvulsants: Potential for elevated phenytoin and carbamazepine levels and clinical anticonvulsant toxicity.
- Serotonergic Drugs
- Drugs that Interfere with Hemostasis (e.g. NSAIDs, Aspirin, Warfarin): May potentiate the risk of bleeding.
- Drugs Tightly Bound to Plasma Proteins: May cause a shift in plasma concentrations.
- Olanzapine: When used in combination with PROZAC, also refer to the Drug Interactions section of the package insert for Symbyax.
- Drugs that Prolong the QT Interval: Do not use Prozac with thioridazine or pimozide. Use with caution in combination with other drugs that prolong the QT interval.
Who makes PROZAC?
Eli Lilly & Company
Is PROZAC safe in pregnancy?
Based on data from published observational studies, exposure to SSRIs, particularly in the month before delivery, has been associated with a less than 2-fold increase in the risk of postpartum hemorrhage.
There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to antidepressants
during pregnancy. Healthcare providers are encouraged to register patients by calling the National Pregnancy Registry for Antidepressants at 1-844-405-6185 or visiting online at MGH Center for women mental health. You should talk to your healthcare provider before taking this medication if you are pregnant.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects in the USDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my PROZAC prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your PROZAC prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient PROZAC savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient PROZAC savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for PROZAC | Canadian Prescription Savings* for PROZAC | PROZAC Drug Coupon* | PROZAC Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of PROZAC?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for PROZAC | Canadian Prescription Savings* for PROZAC | PROZAC Drug Coupon* | PROZAC Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the PROZAC savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the PROZAC drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for PROZAC, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the PROZAC prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, PROZAC is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed PROZAC for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the PROZAC prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the PROZAC prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for PROZAC
If you are having trouble paying for your PROZAC medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for PROZAC you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- PROZAC is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers PROZAC
- If PROZAC is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for PROZAC
If you are having trouble paying for your PROZAC medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for PROZAC you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers PROZAC
- If PROZAC is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for PROZAC
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your PROZAC treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for PROZAC you will need to meet the following criteria:
- You must be currently insured and have coverage for PROZAC
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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