Azithromycin Generic

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Azithromycin
    Generic for Zithromax
    30 tablets $8.1 USD
    Save $142.20
  3. Azithromycin
    Generic for Zithromax
    50 tablets $14.1 USD
    Save $236.40
  4. Azithromycin
    Generic for Zithromax
    100 tablets $24.3 USD
    Save $476.70
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Do you need a prescription for azithromycin?

Yes, azithromycin is only available with a valid physician Rx.

How much is azithromycin without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase azithromycin, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for azithromycin in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a azithromycin savings card?

Yes. Save up to 90% on your azithromycin with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a azithromycin coupon provider in the US?

No. Now Patient does not provide azithromycin coupons or FREE azithromycin samples.

Do you accept commercial, Medicare or Medicaid coverage for azithromycin in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much azithromycin?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using azithromycin. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much azithromycin. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic azithromycin?

Generic azithromycin refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of azithromycin

Azithromycin is approved by the U.S. Food and Drug Administration (FDA) for the treatment of various bacterial infections.

Active ingredient of azithromycin

The active ingredient of azithromycin is azithromycin dihydrate.

US brand name of azithromycin and manufacturer

Azithromycin is available in the US under various brand names, including Zithromax and Z-Pak. It is manufactured by various pharmaceutical companies.

UK brand name of azithromycin and manufacturer

In the UK, azithromycin is available under various brand names, including Zithromax and Clamelle. The manufacturer may vary depending on the brand name.

Prescription requirement for azithromycin

A prescription (Rx) is required for azithromycin in both the US and the UK.

Availability of azithromycin in the UK with NHS prescription

Azithromycin is available in the UK with an NHS prescription.

Conditions treated by azithromycin

Some of the common conditions that azithromycin is used to treat include:

  • Azithromycin is often prescribed for respiratory infections such as bacterial sinusitis, bronchitis, and community-acquired pneumonia. It helps in alleviating symptoms, reducing the duration of the infection, and preventing complications
  • Azithromycin can be used to treat skin and soft tissue infections caused by susceptible bacteria. It is effective against conditions like cellulitis, impetigo, and erysipelas
  • Azithromycin is an option for the treatment of certain STIs, including genital chlamydia and gonorrhea. It is commonly prescribed as a single dose or as a short course of treatment
  • Azithromycin is sometimes used to treat middle ear infections (otitis media) and throat infections (pharyngitis or tonsillitis) caused by specific bacteria
  • Azithromycin may be prescribed for the treatment of travelers’ diarrhea caused by enterotoxigenic Escherichia coli (ETEC) or Campylobacter species

Azithromycin will not treat a viral infection such as the flu or a common cold.

How does azithromycin work?

Azithromycin belongs to a class of medications called macrolide antibiotics. It works by inhibiting the growth and multiplication of bacteria. Azithromycin interferes with the protein synthesis process in bacteria, preventing them from producing the proteins necessary for their survival and replication.

Forms of azithromycin available

Azithromycin is available in the form of oral tablets, capsules, and oral suspension.

Dosage of azithromycin

The dosage of azithromycin may vary depending on the specific bacterial infection being treated, the patient’s age and weight, and other individual factors. It is important to follow the prescribed dosage instructions the healthcare provider provides. If you miss a dose of azithromycin, it is important to take the missed dose as soon as you remember unless it is close to the time for your next scheduled dose. In that case, it is best to skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for the missed one. Missing a dose may decrease the drug’s effectiveness against the bacteria, so it is generally recommended to take the missed dose as soon as possible. Remember, it is important to complete the full course of antibiotics as prescribed, even if you miss a dose. Skipping doses or stopping treatment prematurely may lead to the development of antibiotic-resistant bacteria and can hinder the effectiveness of future treatments.

Directions for azithromycin use

Azithromycin should be taken exactly as directed by the healthcare provider. The medication is usually taken once daily, with or without food. It is important to complete the full course of treatment, even if symptoms improve before the medication is finished. Store at room temperature away from moisture and heat.

Warnings and precautions for azithromycin

  • Azithromycin should be used with caution in individuals with certain medical conditions, such as liver or kidney problems. Dose adjustments may be necessary
  • It may interact with certain medications, including antacids containing aluminium or magnesium, which can reduce the absorption of azithromycin, so it is generally recommended to take them at least 2 hours apart
  • Medications that prolong the QT interval or cause irregular heart rhythms, such as certain antiarrhythmics, antipsychotics, and antidepressants, can potentially increase the risk of a rare but serious heart conditions called QT prolongation which is life-threatening. Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation
  • In rare cases, azithromycin can cause allergic reactions including anaphylaxis and angioedema, which can be life-threatening and require immediate medical attention. Symptoms may include rash, itching, swelling of the face, lips, or tongue, and trouble breathing. If you experience any signs of an allergic reaction, it is crucial to stop taking the medication and seek immediate medical help
  • While extremely rare, azithromycin has been associated with liver problems such as hepatitis and abnormal liver function tests. If you notice any yellowing of the skin or eyes, dark urine, or persistent abdominal pain, it is important to contact your healthcare provider
  • Use caution in patients with myasthenia gravis (exacerbation may occur)
  • Azithromycin may interact with warfarin, a blood thinner, and cause an increased risk of bleeding. Regular monitoring of blood clotting factors is recommended if both medications are taken together
  • Azithromycin can increase the levels of digoxin, a medication used for heart problems. Regular monitoring of digoxin levels is important when using azithromycin simultaneously, to reduce the risk of toxicity
  • Inform your doctor if you have experienced adverse effects with other antibiotics such as erythromycin, clarithromycin and telithromycin
  • It is crucial to inform a healthcare professional about all the medications you are taking, including over-the-counter drugs and supplements to prevent drug interactions

Use of azithromycin during pregnancy

The use of azithromycin during pregnancy should be carefully considered, and the potential risks and benefits should be discussed with a healthcare provider.

Use of azithromycin while breastfeeding

Azithromycin is excreted in breast milk but is generally considered safe to use while breastfeeding. It is recommended to consult a healthcare provider before using azithromycin while breastfeeding.

Possible side effects of azithromycin

In clinical trials common side effects of azithromycin are gastrointestinal related including diarrhea, nausea, abdominal pain, and headache. Serious side effects are rare but can occur. Promptly report any concerning symptoms to a healthcare provider.

Similar drugs to azithromycin

Other macrolide antibiotics used for the treatment of bacterial infections include clarithromycin and erythromycin.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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