Acetazolamide Generic

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  1. Medication
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  2. Acetazolamide
    Generic for Diamox
    30 tablets $9.3 USD
    Save $60.30
  3. Acetazolamide ER
    Generic for Diamox Sequels
    30 extended release capsules $8.1 USD
    Save $128.40
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Do you need a prescription for acetazolamide?

Yes, acetazolamide is only available with a valid physician Rx.

How much is acetazolamide without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase acetazolamide, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for acetazolamide in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a acetazolamide savings card?

Yes. Save up to 90% on your acetazolamide with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a acetazolamide coupon provider in the US?

No. Now Patient does not provide acetazolamide coupons or FREE acetazolamide samples.

Do you accept commercial, Medicare or Medicaid coverage for acetazolamide in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much acetazolamide?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using acetazolamide. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much acetazolamide. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic acetazolamide?

Generic acetazolamide refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of acetazolamide

Acetazolamide is approved by the U.S. Food and Drug Administration (FDA) for the treatment of various conditions, including glaucoma, edema, epilepsy, and altitude sickness.

Active ingredient of acetazolamide

The active ingredient of acetazolamide is acetazolamide.

US brand name of acetazolamide and manufacturer

Acetazolamide is available in the US under various brand names, including Diamox and Diamox Sequels. The manufacturers may vary depending on the brand names.

UK brand name of acetazolamide and manufacturer

In the UK, acetazolamide is available under various brand names, including Diamox and acetazolamide. The manufacturer may vary depending on the brand name.

Prescription requirement for acetazolamide

A prescription (Rx) is required for acetazolamide in both the US and the UK.

Availability of acetazolamide in the UK with NHS prescription

Acetazolamide is available in the UK with an NHS prescription.

Conditions treated by acetazolamide

Acetazolamide is used for the treatment of various conditions including open-angle glaucoma, secondary glaucoma, and acute angle-closure glaucoma before surgery to lower pressure inside the eye. It may also be used to treat congestive heart failure, edema (swelling), epilepsy (seizures), and high altitude sickness/acute mountain sickness (to prevent or reduce symptoms).

How does acetazolamide work?

Acetazolamide is a diuretic and carbonic anhydrase inhibitor medication. Its chemical structure consists of sulfonamide and nitrogen groups, which inhibit the action of carbonic anhydrase enzymes in various tissues. This inhibition leads to a decrease in bicarbonate formation, resulting in metabolic acidosis. The mechanism of action for acetazolamide involves reducing intraocular pressure by decreasing aqueous humor production and improving respiratory alkalosis.

Forms of acetazolamide available

Acetazolamide is available in various dosage forms, including oral tablets and extended-release capsules.

Dosage of acetazolamide

The dosage of acetazolamide may vary depending on the specific condition being treated, the severity of the condition, and other individual factors. It is important to follow the recommended dosage instructions provided by the healthcare provider.

Directions for use of acetazolamide

Acetazolamide should be taken as directed by the healthcare provider. The specific instructions may include the timing of administration, dosage adjustments, and any necessary precautions. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Warnings and contraindications for acetazolamide

  • Acetazolamide may cause side effects such as frequent urination, loss of appetite, taste changes, and drowsiness. It is important to discuss any concerning symptoms with a healthcare provider
  • Acetazolamide may interact with certain medications such as aspirin, digoxin, phenytoin, cyclosporine, sodium bicarbonate, lithium, quinidine, primidone, amphetamines, and salicylates. It is important to inform your healthcare provider about all the medications including supplements you are taking before starting acetazolamide
  • Drug interactions with other medications that may require dosage adjustments of acetazolamide or close monitoring when used concomitantly
  • People with a history of liver disease, cirrhosis or kidney disease should use acetazolamide cautiously
  • You should not use acetazolamide if you have an electrolyte imbalance, or adrenal gland failure
  • Individuals who are allergic to sulfa drugs should not take acetazolamide
  • Pregnant women and breastfeeding mothers should consult their healthcare provider before using this medication

Possible side effects of acetazolamide

Common side effects of acetazolamide may include frequent urination, loss of appetite, low blood potassium, taste changes, drowsiness, and tingling sensations. If these adverse effects persist or worsen, it is important to contact a healthcare provider. Allergic reactions or gastrointestinal upset, and neurological signs are seen when given in high doses.

Similar drugs to acetazolamide

Other medications used for the treatment of glaucoma and edema include other carbonic anhydrase inhibitors, such as dorzolamide and brinzolamide.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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