acarbose
Used for Type 2 Diabetes
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Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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acarbose Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is acarbose available in?
acarbose is available as a 50 mg and 100 mg oral tablet.
What is acarbose used for?
acarbose is an alpha-glucosidase inhibitor that is used to treat type 2 diabetes.
How does acarbose work?
acarbose temporarily blocks a protein called alpha-glucosidase, which slows down the digestion of carbohydrates in your gut. As a result, your body will absorb less sugar from the foods that you eat. And this leads to lower blood sugar levels after you eat.
How do I take acarbose?
acarbose is typically started at a low dose and then gradually increased. The average
adult dose is 100 mg acarbose three times daily. A further increase to 200 mg acarbose three
times daily may occasionally be necessary.
Is it safe for me to take acarbose?
acarbose is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following.
Hypersensitivity to acarbose and/or any of the inactive tablet constituents, pregnancy and lactation.
acarbose should not be used in patients under 18 years of age.
acarbose is contraindicated in patients with severe renal impairment (creatinine clearance <
25 mL/min).
acarbose should not be used in patients with gastrointestinal disorders associated with
malabsorption. It should not be used in patients with inflammatory bowel disease, such as ulcerative
colitis and Crohn’s disease.
acarbose should not be used in patients with partial intestinal obstruction, or in patients predisposed
to intestinal obstruction or ileus.
Similarly, acarbose should not be used in conditions that could be aggravated by an increased
formation of intestinal gas (e.g. Roemhelds syndrome, major hernias, intestinal obstruction and intestinal
ulcers).
acarbose Common Side Effects
- Common side effects of acarbose:
- Excessive gas
- Diarrhea
- Stomach pain
acarbose Serious Side Effects
Serious side effects are rare with acarbose.
Effects of other drugs, drug classes and over-the-counter products on acarbose
- The following medications may interact with acarbose:
- Oral antidiabetic agents: When acarbose is prescribed in addition to existing treatment with
- sulfonylureas, or metformin, the dosage of the sulfonylurea or metformin must be appropriately reduced
- should the blood glucose levels fall in the hypoglycaemic range. In individual cases hypoglycaemiarelated impairment of consciousness may occur.
- Neomycin: Due to neomycin-induced malabsorption of carbohydrate, concomitant administration of
- neomycin may lead to an enhanced reduction of postprandial blood glucose and to an increase in the
- frequency and severity of gastrointestinal adverse reactions. If the symptoms are severe, a temporary
- dose reduction of acarbose may be warranted.
- Cholestyramine: The concomitant administration of cholestyramine may enhance the effects of
- acarbose, particularly the reduction of postprandial insulin levels. If both acarbose and
- cholestyramine therapy are withdrawn simultaneously, caution should be exercised as a rebound
- phenomenon has been observed in non-diabetic subjects.
- Digoxin: In individual cases, acarbose may affect digoxin bioavailability, which may require dose
- adjustment of digoxin.
- Intestinal Adsorbents: On the basis of general considerations, the simultaneous use of intestinal
- adsorbents (e.g. charcoal), and digestive enzyme preparations (e.g. amylase, pancreatin) may reduce the
- effect of acarbose and should be avoided wherever possible.
- Antacids: The concomitant administration of acarbose and antacids does not alter the effect of
- acarbose. The administration of antacid preparations is unlikely to ameliorate the gastrointestinal
- symptoms of acarbose and therefore should not be recommended for this purpose.
Who makes acarbose?
Various FDA-approved generic manufacturers
Is acarbose safe in pregnancy?
acarbose should not be administered during pregnancy as no information from controlled clinical
studies is available on its use in pregnant women.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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