DeferasiroxPrices, Coupons & Savings
Mail Order Pharmacy
- MedicationYou saveUS ONLY
- DeferasiroxGeneric for JadenuRx90mg20 tablets $12 USD20 tablets $12 USD - $0.6 USD/tabletSave $1543.20
- DeferasiroxGeneric for JadenuRx180mg30 tablets $15 USD30 tablets $15 USD - $0.5 USD/tabletSave $2317.80
- DeferasiroxGeneric for JadenuRx360mg55 tablets $27.3 USD55 tablets $27.3 USD - $0.5 USD/tabletSave $4249.50
Do you need a prescription for deferasirox?
Yes, deferasirox is only available with a valid physician Rx.
How much is deferasirox without Insurance in the US?
Our website gives two competitive savings options to US customers who wish to purchase deferasirox, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.
What will my out-of-pocket cost be for deferasirox in the US?
There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.
Is Now Patient a deferasirox savings card?
Yes. Save up to 90% on your deferasirox with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.
Can you handle Rx transfers for home delivery in the US?
Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.
Is Now Patient a deferasirox coupon provider in the US?
No. Now Patient does not provide deferasirox coupons or FREE deferasirox samples.
Do you accept commercial, Medicare or Medicaid coverage for deferasirox in the US?
No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.
Does Now Patient work with Medicare?
Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.
Does Now Patient work with Commercial Insurance?
Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.
What should you do if you use too much deferasirox?
Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using deferasirox. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much deferasirox. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.
If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.
What should I do if I miss my dose?
There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.
Click here to find out what to do if you forgot to take your medication
US brand name of deferasirox and manufacturer
Deferasirox is available under the brand names Jadenu and Exjade, which is manufactured by Novartis Pharmaceuticals Corporation.
UK brand name of deferasirox and manufacturer
In the UK, deferasirox is available under the brand name Exjade, which is manufactured by Novartis Pharmaceuticals.
Availability of deferasirox
Deferasirox is available by prescription only.
FDA approval of deferasirox
Deferasirox has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of chronic iron overload due to blood transfusions in patients aged 2 years and older and for the treatment of chronic iron overload in non-transfusion-dependent thalassemia syndromes in patients aged 10 years and older.
NHS prescription (UK) for deferasirox
Deferasirox may be available in the UK with an NHS prescription. It is important to consult with your healthcare provider or pharmacist to verify availability.
Mechanism of action
Deferasirox is an iron chelator, which means it binds to excess iron in the body and helps to remove it. It works by forming a complex with iron, which is then excreted in the urine or feces. This helps to reduce the iron burden in patients with iron overload conditions.
Uses of deferasirox
Deferasirox is a medication primarily used for the treatment of chronic iron overload in people who receive regular blood transfusions. Here are some of the main uses of deferasirox:
- Deferasirox is commonly used in the management of thalassemia, a genetic blood disorder that causes abnormal hemoglobin production. People with thalassemia often require frequent blood transfusions, leading to iron buildup in the body. Deferasirox helps to remove excess iron and prevent iron-related complications
- Individuals with sickle cell disease often receive blood transfusions to manage their condition. As a result, they can also develop iron overload. Deferasirox can be used to reduce iron levels and minimize the risk of iron toxicity
- Deferasirox is also beneficial for people with other transfusion-dependent anemias, such as myelodysplastic syndromes (MDS), aplastic anemia, and other rare blood disorders. It helps to remove the excess iron accumulated from regular transfusions
- Although the primary use of deferasirox is for iron overload caused by blood transfusions, it may also be employed in cases where iron accumulation occurs due to other reasons, such as excessive dietary iron absorption or certain genetic conditions
Dosage of deferasirox and directions
The dosage of deferasirox is determined by factors such as the patient’s age, weight, serum ferritin levels, and the presence or absence of transfusion-dependent anemia. It is important to note that the dosage should be individualized and prescribed by a healthcare professional who is experienced in managing iron overload.
For adults and children aged 2 years of age and older with transfusional iron overload, the initial recommended dosage is 20 mg per kilogram of body weight per day. This can be increased up to a maximum of 30 mg per kilogram of body weight per day based on the patient’s response and tolerance.
For non-transfusion-dependent thalassemia patients aged 10 years and older, the recommended starting dosage is 10 mg per kilogram of body weight per day. The dosage can be increased up to a maximum of 20 mg per kilogram of body weight per day.
It is important to follow the dosage instructions provided by the healthcare professional and not exceed the recommended maximum dosage. Regular monitoring of serum ferritin levels and other relevant laboratory tests is necessary to assess the response to treatment and adjust the dosage if needed.
It is worth noting that deferasirox is available in different formulations such as tablets, dispersible tablets, and granules for oral suspension. The healthcare professional will determine the appropriate formulation and dosage based on the patient’s specific needs and preferences.
It is important to take deferasirox exactly as prescribed by your healthcare provider. Do not adjust the dosage or stop taking the medication without consulting your doctor.
It is recommended to take deferasirox on an empty stomach, at least 30 minutes before a meal. However, if you experience gastrointestinal discomfort, it is permissible to take it with a light meal.
Taking deferasirox tablets with food may slightly decrease its absorption into the body. To ensure optimal effectiveness of the medication, it is best to follow the instructions and take it on an empty stomach whenever possible. Administer granules by sprinkling the full dose on soft food (eg, yogurt or apple sauce) immediately before use and administered orally.
Store at room temperature, away from moisture and heat.
Is it safe to take deferasirox if I am pregnant or planning on becoming pregnant?
The safety of deferasirox in pregnancy has not been well established. If you are pregnant, planning to become pregnant or suspect you may be pregnant, it is important to discuss the use of deferasirox with your healthcare provider. They can evaluate the potential risks and benefits to determine the best course of action for your specific situation.
Is it safe to take deferasirox while breastfeeding?
It is not recommended to breastfeed while taking deferasirox. It is important to consult with your healthcare provider for specific guidance on the use of deferasirox while breastfeeding.
When taking any medication, it is important to be aware of potential drug interactions. Although deferasirox is generally safe to use, it can interact with other drugs, which may affect its effectiveness or cause unwanted side effects. It is crucial to inform your healthcare provider about all the medications, over-the-counter drugs, supplements, and herbal remedies you are taking, as well as any medical conditions you have, before starting treatment with deferasirox.
- One of the most significant drug interactions associated with iron-chelating agents such as deferasirox is with aluminum-containing antacids. These include common over-the-counter antacids which are used to relieve heartburn or indigestion. When taken together, deferasirox and aluminium-containing antacids can bind to each other in the digestive tract, reducing the absorption of both medications. It is recommended to separate the administration of deferasirox and aluminium-containing antacids by at least two hours to avoid this interaction
- Certain medications can increase the concentration of deferasirox in the blood, potentially leading to an increased risk of side effects. One such example is drugs that inhibit the enzyme CYP3A4, which is responsible for the breakdown of deferasirox. Examples of medications that can increase deferasirox blood levels include ketoconazole, itraconazole, clarithromycin, and ritonavir. It is important to monitor for signs of toxicity or adverse effects when combining deferasirox with these drugs
- Deferasirox can cause kidney damage, so combining it with other medications that have similar effects on the kidneys may increase the risk. Examples of such drugs include nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen, certain antibiotics such as gentamicin or vancomycin, and certain antifungal medications like amphotericin B
- You should not use deferasirox if you have severe kidney disease or liver disease, advanced cancer, a blood cell or bone marrow disorder, or low levels of platelets in your blood
- Deferasirox can also interact with other medications and affect their effectiveness. For example, deferasirox may reduce the effectiveness of hormonal contraceptives, such as birth control pills, patches, or implants. It is recommended to use alternative or additional methods of contraception while taking deferasirox
- Cholestyramine, a medication used to lower cholesterol levels, may decrease the absorption of deferasirox. It is recommended to separate the administration of cholestyramine and deferasirox by at least 2 hours
Side effects of deferasirox
Common side effects in clinical trials:
Deferasirox may cause some common gastrointestinal side effects, such as nausea, vomiting, and diarrhea. These symptoms are usually mild and improve over time. It is important to stay hydrated and eat small, frequent meals to help manage these side effects.
Serious side effects:
While rare, serious adverse events can occur with deferasirox treatment. These include liver problems, kidney damage, and severe allergic reactions. If you experience symptoms such as yellowing of the skin or eyes, dark urine, loss of appetite, difficulty breathing while taking deferasirox, or vomit that looks like coffee grounds, seek medical attention immediately. Kidney problems like decreased urine output are also possible and should not be ignored. Regular monitoring by your healthcare provider can help identify any potential serious adverse reactions early on.
If you have signs of an allergic reaction (hives, difficulty breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, a red or purple skin rash that spreads and causes blistering and peeling) seek immediate medical attention.
It is important to note that this is not an exhaustive list of side effects. For a complete list, refer to the medication leaflet or consult your healthcare provider.
Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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