ocrelizumab
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Manufactured by various FDA-approved generic manufacturers.
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ocrelizumab Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is ocrelizumab available in?
ocrelizumab is available as a 300 mg/10 mL (30 mg/mL) single-dose vial.
What is ocrelizumab used for?
ocrelizumab is a monoclonal antibody that is used to treat all types of multiple sclerosis (MS).
How does ocrelizumab work?
ocrelizumab is a monoclonal antibody. It’s not exactly known how the medication works, but it’s thought to work by attaching to certain proteins on the surface of immune cells to change how they function. This might help lower inflammation and symptoms of MS.
How do I take ocrelizumab?
You’ll receive 300 mg injected into the veins (intravenously or IV) every 2 weeks for the first two treatments. Then, you’ll receive 600 mg IV every 6 months for your following treatments.
Is it safe for me to take ocrelizumab?
ocrelizumab is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have any of the following.
- Active hepatitis B virus infection
- History of life-threatening infusion reaction to ocrelizumab
ocrelizumab Common Side Effects
Common side effects of ocrelizumab:
- Upper respiratory tract infections
- Infusion reactions
- Skin infections
- Lower respiratory tract infections
- Back pain
ocrelizumab Serious Side Effects
Serious side effects are rare with ocrelizumab. Contact your healthcare provider immediately if you experience any of the following.
- Serious allergic reactions: hives, rash, itching, dizziness, fever, shaking, flushing, trouble breathing, chest pain
Effects of other drugs, drug classes and over-the-counter products on ocrelizumab
The following medications may interact with ocrelizumab:
- The concomitant use of ocrelizumab and other immune-modulating or immunosuppressive therapies, including
- immunosuppressant doses of corticosteroids, is expected to increase the risk of immunosuppression
- The safety and effectiveness of live or live-attenuated vaccines administered concomitantly with ocrelizumab have not been assessed.
Who makes ocrelizumab?
Various FDA-approved generic manufacturers
Is ocrelizumab safe in pregnancy?
It is not known if ocrelizumab will harm your unborn baby. You should use birth control (contraception) during treatment with ocrelizumab and for 6 months after your last infusion of ocrelizumab. Talk with your healthcare provider about what birth control method is right for you during this time .Pregnancy Registry. There is a pregnancy registry for women who take ocrelizumab during pregnancy. If you become pregnant while receiving ocrelizumab, tell your healthcare provider right away. Talk to your healthcare provider about registering with the ocrelizumab Pregnancy Registry. The purpose of this registry is to collect information about your health and your baby’s health. Your healthcare provider can enroll you in this registry by calling 1-833-872-4370
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
Drug Savings Tips
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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