Key facts about Metformin
What dosages is Metformin available in?
Metformin is available as a 500 mg and 1,000 mg extended-release oral tablet.
What is Metformin used for?
Metformin is a biguanide that is used to treat type 2 diabetes.
How does Metformin work?
Metformin is a biguanide, which uses many methods to lower your blood sugar. It lowers the amount of sugar your body makes and absorbs from food. It also helps your body respond better to insulin.
How do I take Metformin?
Metformin is typically taken by mouth with a starting dose is 500 mg with your evening meal. If needed, your provider might raise your dose as long as you’re not having bad side effects. The maximum total dose is 2,000 mg daily.
Is it safe for me to take Metformin?
Metformin is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have severe renal impairment (eGFR below 30 mL/min/1.73 m2), a hypersensitivity to Metformin, or acute or chronic metabolic acidosis, including diabetic ketoacidosis, with or without coma.
Metformin Common Side Effects
Common side effects of Metformin include:
- Diarrhea
- Nausea and vomiting
- Stomach pain
- Constipation
- Bloating
- Heartburn
- Gas
- Dizziness
- Headache
Metformin Serious Side Effects
Serious side effects are rare with Metformin. Contact your healthcare provider immediately if you experience any of the following.
- Lactic acidosis: muscle pain, severe abdominal pain, shallow breathing, tiredness, weakness, change in heartbeat
Effects of other drugs, drug classes and over-the-counter products on Metformin
The following medications may interact with Metformin:
- Carbonic anhydrase inhibitors – May increase risk of lactic acidosis
- Drugs that reduce Metformin clearance (such as ranolazine, vandetanib, dolutegravir, and cimetidine) – May increase the accumulation of Metformin
- Alcohol – Can potentiate the effect of Metformin on lactate metabolism
Who makes Metformin?
Various FDA-approved generic manufacturers
Is Metformin safe in pregnancy?
It is not known if Metformin will harm your unborn baby. You should talk to your healthcare provider before taking this medication if you are pregnant.
