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Glucophage is the brand name for metformin and is available as an oral tablet.

Glucophage is available as a 500 mg, 850 mg, and 1000 mg oral tablet.

Glucophage is a biguanide that is used to treat type 2 diabetes.

Glucophage is a biguanide, which uses many methods to lower your blood sugar. It lowers the amount of sugar your body makes and absorbs from food. It also helps your body respond better to insulin.

Glucophage is typically started as 500 mg by mouth twice daily or 850 mg by mouth once daily. Depending on how well it works, the dose can be raised to a total of 2,550 mg by mouth per day split into a few doses throughout the day.

Glucophage is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have severe renal impairment (eGFR below 30 mL/min/1.73 m2), a hypersensitivity to metformin, or acute or chronic metabolic acidosis, including diabetic ketoacidosis, with or without coma.

Common side effects of Glucophage include:

• Diarrhea
• Nausea and vomiting
• Stomach pain
• Constipation
• Bloating
• Heartburn
• Gas
• Dizziness
• Headache

Serious side effects are rare with Glucophage. Contact your healthcare provider immediately if you experience any of the following.

• Lactic acidosis: muscle pain, severe abdominal pain, shallow breathing, tiredness, weakness, change in heartbeat

The following medications may interact with Glucophage:

• Carbonic anhydrase inhibitors – May increase risk of lactic acidosis
• Drugs that reduce metformin clearance (such as ranolazine, vandetanib, dolutegravir, and cimetidine) – May increase the accumulation of metformin
• Alcohol – Can potentiate the effect of metformin on lactate metabolism

Bristol-Myers Squibb

It is not known if Glucophage will harm your unborn baby. You should talk to your healthcare provider before taking this medication if you are pregnant.

• Metformin