indomethacin
Used for Pain & Inflammation and Gout
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Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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indomethacin Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is indomethacin available in?
indomethacin is available as a 75 mg extended-release oral capsule.
What is indomethacin used for?
indomethacin is a NSAID and is used to treat moderate-to-severe rheumatoid arthritis, including flare-ups, moderate-to-severe ankylosing spondylitis, moderate-to-severe osteoarthritis, shoulder pain caused by bursitis or tendonitis, and gouty arthritis.
How does indomethacin work?
indomethacin is a nonsteroidal anti-inflammatory drug, or better known as an NSAID. It works by blocking proteins in the body called cyclooxygenase (COX) that cause inflammation, swelling, and pain. This helps lessen inflammation, swelling, and pain from your condition.
How do I take indomethacin?
indomethacin is typically dosed as 75 mg by mouth once a day.
Is it safe for me to take indomethacin?
indomethacin is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs or for the treatment of peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery.
indomethacin Common Side Effects
Common side effects of indomethacin include:
- Headache
- Dizziness
- Nausea
- Stomach upset
indomethacin Serious Side Effects
Serious side effects are rare with indomethacin. Contact your healthcare provider immediately if you experience any of the following.
- Stomach bleeding: feeling faint, vomiting blood, bloody or dark stools, severe stomach pain or discomfort
- Heart attack: chest pain or tightness; pain that radiates up to your shoulder, arm, neck, or jaw
- Heart failure: trouble breathing, swelling, fast heartbeat, sudden weight gain
- Stroke: sudden confusion, trouble breathing, weakness on one side of your body or face, slurred speech
- Worsening liver problems or liver failure: swelling of your stomach, yellowing of your skin or the whites of your eyes, confusion, dark or brown urine
- Serious kidney problems: tiredness, dry and itchy skin, low appetite, urinating less than usual, foamy or bloody urine, muscle cramps
- Allergic reactions: hives, rash, blisters, swelling of the lips or tongue, trouble breathing
- Serious skin reactions: skin reddening, skin peeling, blisters, rash
Effects of other drugs, drug classes and over-the-counter products on indomethacin
The following medications may interact with indomethacin:
- ACE-Inhibitors and Angiotensin II Antagonists: Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors and angiotensin II antagonists. indomethacin can reduce the antihypertensive effects of captopril and losartan
- Aspirin: The use of indomethacin in conjunction with aspirin or other salicylates is not recommended
- Beta-adrenoceptor blocking agents: Blunting of the antihypertensive effect of beta-adrenoceptor blocking agents by non-steroidal antiinflammatory drugs including indomethacin has been reported
- Cyclosporine: Administration of non-steroidal anti-inflammatory drugs concomitantly with cyclosporine has been associated with an increase in cyclosporine-induced toxicity
- Digoxin: indomethacin given concomitantly with digoxin has been reported to increase the serum concentration and prolong the half-life of digoxin
- Probenecid: When indomethacin is given to patients receiving probenecid, the plasma levels of indomethacin are likely to be increased
Who makes indomethacin?
Various FDA-approved generic manufacturers
Is indomethacin safe in pregnancy?
It’s not completely clear whether indomethacin is safe to take during the first 20 weeks of pregnancy. But you should avoid indomethacinafter 20 weeks of pregnancy because it might cause developmental problems in your unborn baby or complications during delivery.
What to do if you missed your indomethacin dose
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Tips
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
Things to know
Is indomethacin a strong painkiller?
What is the most common side effect of indomethacin?
Who Cannot take indomethacin?
What organ does indomethacin damage?
What painkiller can I take with indomethacin?
Does indomethacin cause weight gain?
Is 50 mg of indomethacin a lot?
What is stronger indomethacin or prednisone?
Is indomethacin bad for kidneys?
What to avoid when taking indomethacin?
How do I protect my stomach with indomethacin?
Which is safer ibuprofen or indomethacin?
Is indomethacin hard on the kidneys?
What pain reliever can I take with indomethacin?
Can I take indomethacin and ibuprofen at same time?
Can I drink alcohol 5 hours after taking indomethacin?
How much stronger is indomethacin than ibuprofen?
What is the strongest anti-inflammatory drug?
Can I mix indomethacin and ibuprofen?
Does indomethacin make you sleepy?
Is indomethacin the strongest NSAID?
Is too much indomethacin bad for you?
How much indomethacin can I take at once?
Which painkiller is best for inflammation?
How quickly does indomethacin work?
Which is better for pain indomethacin or ibuprofen?
What kind of pain does indomethacin treat?
Can I lay down after taking indomethacin?
How many days should you take indomethacin for gout?
Does indomethacin 50 mg make you sleepy?
When should you not take indomethacin?
Why does indomethacin work so well?
What happens when you take indomethacin?
How powerful is indomethacin?
How many indomethacin can I take at once?
What should I eat before taking indomethacin?
Can I take indomethacin and ibuprofen in the same day?
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