INDOCIN
Used for Gout and Pain & Inflammation
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Manufactured by Merck & Co., Inc.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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You can lower cost of your INDOCIN using one of the 4 following drug savings programs
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INDOCIN Uses, Side Effects, Interactions, Warnings & Dosing
What is INDOCIN?
INDOCIN is the brand name for indomethacin and is available as an oral capsule and a suppository.
What dosages is INDOCIN available in?
INDOCIN is available as a 25 mg and 50 mg oral capsule as well as a 50 mg suppository.
What is INDOCIN used for?
INDOCIN is a NSAID and is used to treat moderate-to-severe rheumatoid arthritis, including flare-ups, moderate-to-severe ankylosing spondylitis, moderate-to-severe osteoarthritis, shoulder pain caused by bursitis or tendonitis, and gouty arthritis.
How does INDOCIN work?
INDOCIN is a nonsteroidal anti-inflammatory drug, or better known as an NSAID. It works by blocking proteins in the body called cyclooxygenase (COX) that cause inflammation, swelling, and pain. This helps lessen inflammation, swelling, and pain from your condition.
How do I take INDOCIN?
INDOCIN is typically dosed as 50 mg to 200 mg by mouth per day, split up into 2 or 4 doses throughout the day.
Is it safe for me to take INDOCIN?
INDOCIN is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs or for the treatment of peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery.
INDOCIN Common Side Effects
Common side effects of INDOCIN include:
- Headache
- Dizziness
- Nausea
- Stomach upset
INDOCIN Serious Side Effects
Serious side effects are rare with INDOCIN. Contact your healthcare provider immediately if you experience any of the following.
- Stomach bleeding: feeling faint, vomiting blood, bloody or dark stools, severe stomach pain or discomfort
- Heart attack: chest pain or tightness; pain that radiates up to your shoulder, arm, neck, or jaw
- Heart failure: trouble breathing, swelling, fast heartbeat, sudden weight gain
- Stroke: sudden confusion, trouble breathing, weakness on one side of your body or face, slurred speech
- Worsening liver problems or liver failure: swelling of your stomach, yellowing of your skin or the whites of your eyes, confusion, dark or brown urine
- Serious kidney problems: tiredness, dry and itchy skin, low appetite, urinating less than usual, foamy or bloody urine, muscle cramps
- Allergic reactions: hives, rash, blisters, swelling of the lips or tongue, trouble breathing
Serious skin reactions: skin reddening, skin peeling, blisters, rash
Effects of other drugs, drug classes and over-the-counter products on INDOCIN
The following medications may interact with INDOCIN:
- ACE-Inhibitors and Angiotensin II Antagonists: Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors and angiotensin II antagonists. INDOCIN can reduce the antihypertensive effects of captopril and losartan
- Aspirin: The use of INDOCIN in conjunction with aspirin or other salicylates is not recommended.
- Beta-adrenoceptor blocking agents: Blunting of the antihypertensive effect of beta-adrenoceptor blocking agents by non-steroidal antiinflammatory drugs including INDOCIN has been reported
- Cyclosporine: Administration of non-steroidal anti-inflammatory drugs concomitantly with cyclosporine has been associated with an increase in cyclosporine-induced toxicity
- Digoxin: INDOCIN given concomitantly with digoxin has been reported to increase the serum concentration and prolong the half-life of digoxin
- Probenecid: When INDOCIN is given to patients receiving probenecid, the plasma levels of indomethacin are likely to be increased
Who makes INDOCIN?
Merck & Co., Inc.
Is INDOCIN safe in pregnancy?
It’s not completely clear whether INDOCIN is safe to take during the first 20 weeks of pregnancy. But you should avoid INDOCIN after 20 weeks of pregnancy because it might cause developmental problems in your unborn baby or complications during delivery.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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