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Cyclobenzaprine is available as a 15 mg and 30 mg extended-release capsule.

Cyclobenzaprine is a muscle relaxant indicated along with rest and physical
therapy for relief of muscle spasm associated with acute (short-term), painful
musculoskeletal conditions in adults.

Cyclobenzaprine is a muscle relaxant. It works in the brain to help relieve muscle spasms, pain, and tenderness.

Cyclobenzaprine is typically taken by mouth once daily around the same time each day for up to 2 or 3 weeks.

Cyclobenzaprine is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not take this medication if you have taken a monoamine oxidase (MAO) inhibitor within the past 14 days, during the acute recovery phase of a heart attack, inpatients with arrhythmias, heart block or conduction disturbances, or congestive heart failure, or if you have hyperthyroidism.

Common side effects of Cyclobenzaprine include:

• Dry mouth
• Dizziness
• Indigestion
• Nausea
• Feeling tired
• Constipation
• Drowsiness

Serious side effects are rare with Cyclobenzaprine. Contact your healthcare provider immediately if you experience any of the following.

• Severe allergic reaction: hives, trouble breathing, swelling of the face, lips, tongue, or throat
• Serotonin syndrome: fast heart rate, dizziness, sweating, fever, shakiness, muscle stiffness, muscle twitching, confusion, hallucinations, coma
• Seizures
• Abnormal heart rhythm

The following medications may interact with Cyclobenzaprine:

• MAO Inhibitors – Life-threatening interactions may occur.
• Serotonergic Drugs – Serotonin syndrome has been reported
• CNS Depressants – Effects of alcohol, barbiturates, and other CNS depressants may be enhanced
• Tramadol – Seizure risk may be enhanced
• Guanethidine – Antihypertensive effect may be blocked

Various FDA-approved generic manufacturers

Cyclobenzaprine use during pregnancy has not shown an identified a drug-associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes. However, you should take with your healthcare provider about the risks of taking Cyclobenzaprine if you become pregnant.

• Amrix
• Flexeril