Cyclobenzaprine Generic

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Cyclobenzaprine
    Generic for Flexeril
    210 tablets $18.3 USD
    Save $109.80
  3. Cyclobenzaprine Extended Release (ER)
    Generic for Amrix
    30 extended release capsules $53.1 USD
    Save $1041.30
  4. Cyclobenzaprine Extended Release (ER)
    Generic for Amrix
    30 extended release capsules $53.1 USD
    Save $1041.30
  5. Cyclobenzaprine
    Generic for Flexeril
    30 tablets $3.9 USD
    Save $14.40
  6. Cyclobenzaprine
    Generic for Flexeril
    30 tablets $3.9 USD
    Save $14.40
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Do you need a prescription for cyclobenzaprine?

Yes, cyclobenzaprine is only available with a valid physician Rx.

How much is cyclobenzaprine without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase cyclobenzaprine, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for cyclobenzaprine in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a cyclobenzaprine savings card?

Yes. Save up to 90% on your cyclobenzaprine with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a cyclobenzaprine coupon provider in the US?

No. Now Patient does not provide cyclobenzaprine coupons or FREE cyclobenzaprine samples.

Do you accept commercial, Medicare or Medicaid coverage for cyclobenzaprine in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much cyclobenzaprine?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using cyclobenzaprine. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much cyclobenzaprine. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic cyclobenzaprine?

Generic cyclobenzaprine refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of cyclobenzaprine

Cyclobenzaprine is approved by the U.S. Food and Drug Administration (FDA) for the short-term relief of muscle spasms associated with acute musculoskeletal conditions.

Active ingredient of cyclobenzaprine

The active ingredient of cyclobenzaprine is cyclobenzaprine hydrochloride.

US brand names of cyclobenzaprine and manufacturers

Cyclobenzaprine is available under various brand names in the US, including Fexmid, Flexeril and Amrix. These medications are manufactured by different pharmaceutical companies.

UK brand names of cyclobenzaprine and manufacturers

In the UK, cyclobenzaprine is not available under any specific brand names.

Prescription requirement for cyclobenzaprine

A prescription (Rx) is required for cyclobenzaprine in both the US and the UK.

Availability of cyclobenzaprine in the UK with NHS prescription

Cyclobenzaprine is not available in the UK or Europe, and its use may be limited. Consultation with a healthcare provider is necessary to determine the availability and prescribing options.

Conditions treated by cyclobenzaprine

Cyclobenzaprine is used for the short-term relief of muscle spasms associated with acute musculoskeletal conditions, such as muscle strains, sprains, or injuries.

How does cyclobenzaprine work?

Cyclobenzaprine works by acting on the central nervous system to reduce muscle spasms. It acts as a muscle relaxant, helping to relieve muscle pain and discomfort.

Forms of cyclobenzaprine available

Cyclobenzaprine is available in various formulations, such as oral tablets or extended-release capsules.

Dosage of cyclobenzaprine

The dosage of cyclobenzaprine may vary depending on the individual patient’s condition, response to treatment, and other factors. It is important to follow the prescribed dosage instructions provided by the healthcare provider.

Directions for cyclobenzaprine use

Cyclobenzaprine should be taken exactly as directed by the healthcare provider. It is usually taken as a short-term treatment for a maximum of 2 to 3 weeks. It is important to avoid sudden discontinuation of the medication and follow the tapering instructions if needed.

Warnings and precautions for cyclobenzaprine

  • Cyclobenzaprine may cause drowsiness or dizziness. It is important to avoid activities requiring alertness until the individual’s response to the medication is known
  • It may interact with certain medications, including monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), and certain other drugs. It is important to inform the healthcare provider about all medications being taken
  • Tell your doctor if you have liver disease, an overactive thyroid (hyperthyroidism), an irregular heartbeat, heartblock, heart failure, or had a recent heart attack, or glaucoma

Use of cyclobenzaprine during pregnancy

The use of cyclobenzaprine during pregnancy should be avoided unless the potential benefits outweigh the risks. Consultation with a healthcare provider is necessary to assess the individual situation.

Use of cyclobenzaprine while breastfeeding

Cyclobenzaprine may pass into breast milk, and its use during breastfeeding is generally not recommended. Consultation with a healthcare provider is necessary to discuss the potential risks and benefits.

Possible side effects of cyclobenzaprine

Common side effects of cyclobenzaprine may include drowsiness, dry mouth, dizziness, constipation, tiredness, and blurred vision. Get medical help right away if you have serious side effects such as a life-threatening allergic reaction. Symptoms include hives, trouble breathing, shortness of breath, swelling of your face, tongue or throat, skin rash, and severe skin reactions. Promptly report any adverse events to a healthcare professional for medical advice.

Interactions with other drugs

Cyproheptadine may interact with other medications, including MAO inhibitors (MAOIs) such as isocarboxazid, phenelzine, rasagiline, selegiline, and tranylcypromine, opioids, benzodiazepines barbiturates such as phenobarbital, sedatives, selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine and paroxetine, selective serotonin and norepinephrine reuptake inhibitors (SNRIs) such as duloxetine, tricyclic antidepressants such as amitriptyline, and imipramine, and tramadol. It is important to inform your healthcare provider about all the prescription drugs, non-prescription over the counter medication, supplements, and vitamins you are taking to avoid potential drug interactions.

Similar drugs to cyclobenzaprine

Other muscle relaxants used for the treatment of muscle spasms include baclofen, tizanidine, and methocarbamol. Please note that the availability, brand names, and prescribing guidelines may vary in different countries. It is important to consult with a healthcare provider for specific information relevant to your location.


  • FDA Prescribing Information for Cyclobenzaprine
  • MHRA product information for Cyclobenzaprine
  • NHS UK


Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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