ZIAC
Used for Hypertension
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Manufactured by Duramed Pharmaceuticals
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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ZIAC Uses, Side Effects, Interactions, Warnings & Dosing
What is ZIAC?
ZIAC is the brand name for bisoprolol/hydrochlorothiazide and is available as an oral tablet.
What dosages is ZIAC available in?
ZIAC is available as a 2.5 mg/6.25 mg, 5 mg/6.25 mg, and 10 mg/6.25 mg oral tablet.
What is ZIAC used for?
ZIAC is a beta-blocker and diuretic that is used to treat high blood pressure.
How does ZIAC work?
ZIAC is a combination of two different medications that both work to lower blood pressure.
Bisoprolol is a cardioselective beta blocker. It works by blocking chemicals that attach to receptors on the heart. This slows down your heart rate and lowers your blood pressure.
Hydrochlorothiazide is a thiazide diuretic (water pill) that makes you urinate more. It works in your kidneys to remove extra water and certain electrolytes, which helps lower your blood pressure.
How do I take ZIAC?
ZIAC is typically started at 2.5 mg/6.25 mg (bisoprolol / hydrochlorothiazide) by mouth once daily. If needed, your provider will raise your dose every 2 weeks. The maximum recommended dose of Ziac is 20 mg/12.5 mg (bisoprolol / hydrochlorothiazide) by mouth once daily.
Is it safe for me to take ZIAC?
ZIAC is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have any of the following:
Sinus bradycardia (a type of slow heartbeat)
Heart block greater than first degree
Shock
Heart failure
Not producing urine
Allergy to sulfa-containing medications
ZIAC Common Side Effects
ZIAC Serious Side Effects
Serious side effects are rare with ZIAC. Contact your healthcare provider immediately if you experience any of the following.
Severe allergic reaction: difficulty breathing, swelling of the tongue, mouth, or throat, hives
Heart failure: trouble breathing, fast weight gain, feeling very tired, chest pain, swelling in the legs, ankles, or feet
Bronchospasm: tightness in the chest, trouble catching your breath, difficulty breathing, wheezing, cough, dizziness, extreme tiredness
Effects of other drugs, drug classes and over-the-counter products on ZIAC
The following medications may interact with ZIAC:
Who makes ZIAC?
Duramed Pharmaceuticals
Is ZIAC safe in pregnancy?
ZIAC hasn’t been well-studied in human pregnancies. But animal studies suggest that it can cause harm to pregnant mothers and unborn babies. Please speak with your healthcare provider right away if you become pregnant or want to become pregnant.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
Drug Savings Tips
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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