ZIAC

Ziac (bisoprolol / hydrochlorothiazide) is a combination of two different medications that both work to lower blood pressure. Bisoprolol is a cardioselective beta blocker. It functions by inhibiting chemicals that attach to receptors on the heart.

This medication may induce or exacerbate heart failure in certain patients. It is essential to consult your healthcare provider immediately if you experience chest pain or discomfort, swollen neck veins, irregular breathing, an irregular heartbeat, facial, finger, feet, or leg swelling, breathing difficulties, weight gain, or unusual tiredness or weakness.

Although hydroCHLOROthiazide and lisinopril are frequently combined, their combined effects may lead to greater blood pressure reduction. It might be necessary to adjust the dosage or conduct special tests to safely use both medications. If you experience a decreased heart rate, dizziness, fainting, or headaches, contact your doctor.

Hydrochlorothiazide is a thiazide diuretic (water pill), while bisoprolol is a beta-blocker. The combination of hydrochlorothiazide and bisoprolol is used to treat high blood pressure (hypertension).

Bisoprolol is marketed under various brand names, including Monocor and Zebeta.

Zebeta (bisoprolol fumarate) is a type of antihypertensive drug known as a beta-adrenergic receptor blocking agent (beta-blocker) utilized in the treatment of hypertension (high blood pressure). Generic versions of Zebeta are also available.

The recommended Ziac dosage and administration typically begin with one 2.5mg/6.25mg tablet taken once daily. Adjustments may be made at 14-day intervals, with a maximum dose of two 10mg/6.25mg tablets (equivalent to 20mg of bisoprolol and 12.5mg of HCTZ) once daily.

Bisoprolol is a beta-blocker medication used for managing high blood pressure (hypertension) and heart failure. For individuals with high blood pressure, taking bisoprolol can help prevent future heart diseases, heart attacks, and strokes.

ZIAC (bisoprolol fumarate and hydrochlorothiazide) is indicated for the treatment of hypertension. It combines two antihypertensive agents in a once-daily dosage: a synthetic beta1-selective (cardioselective) adrenoceptor blocking agent (bisoprolol fumarate) and a benzothiadiazine diuretic (hydrochlorothiazide).

Senior Cardiac Nurse Christopher Allen notes that both Atenolol and bisoprolol are beta-blockers commonly used to treat high blood pressure, angina, and heart failure. However, Atenolol is an older drug and is now less frequently prescribed for cardiac patients, while bisoprolol was developed to be more cardio-specific than Atenolol.

Bisoprolol-HCTZ refers to the generic version of Ziac, a combination medication.

Common side effects of this medication may include a dry, tickly cough that doesn’t improve, dizziness or lightheadedness, particularly upon quick changes in position, headaches, vomiting, diarrhea, mild skin rash or itching, and blurred vision.

ZIAC (bisoprolol fumarate and hydrochlorothiazide) is indicated for the management of hypertension. Bisoprolol is effective in daily doses ranging from 2.5 to 40 mg, while hydrochlorothiazide is effective in doses from 12.5 to 50 mg.

Among commonly prescribed blood pressure medications, ACE inhibitor lisinopril (Prinivil, Zestril) is the most prevalent, followed by the calcium channel blocker amlodipine besylate (Norvasc) and generic hydrochlorothiazide (HCTZ).

The most frequently prescribed blood pressure medications include ACE inhibitors like lisinopril (Prinivil and Zestril), DHP calcium channel blockers such as amlodipine (Norvasc), beta-blockers like metoprolol (Lopressor), and thiazide diuretics like hydrochlorothiazide.

Propranolol and atenolol have been extensively studied for hypertension. For the secondary prevention of myocardial infarction, timolol has the strongest evidence. Sotalol is considered one of the most effective antiarrhythmics among beta-blockers. The best beta-blocker for heart failure is still a subject of ongoing research.

When taking bisoprolol, it’s important to be cautious with alcohol consumption, but otherwise, you can maintain a regular diet and beverage intake. A balanced diet can be beneficial if you have high blood pressure or heart failure.

Bisoprolol may potentially lead to heart failure in some patients. If you experience chest pain or discomfort, dilated neck veins, extreme fatigue, irregular breathing, an irregular heartbeat, shortness of breath, facial, finger, feet, or leg swelling, weight gain, or wheezing, consult your doctor immediately.

Bisoprolol or metoprolol succinate are typically the first-choice beta-blockers for individuals with atrial fibrillation, as they are taken once daily and do not require dose adjustments in patients with renal impairment. Bisoprolol is preferred due to its greater cardioselectivity compared to metoprolol, which may cause more bradycardia.

Before starting bisoprolol, it’s important to inform your doctor if you have ever had an allergic reaction to bisoprolol or any other medication, low blood pressure (hypotension), a slow heart rate, worsening heart failure, a history of heart disease, or if you’ve recently had a heart attack.

Weight gain is not a commonly reported side effect of hydrochlorothiazide. Studies have not indicated weight gain as a typical outcome with this medication.

Continue taking bisoprolol and hydrochlorothiazide as directed by your healthcare provider, even if you feel well. This medication may increase urination frequency. To prevent sleep disturbances, avoid taking it too close to bedtime.

Both drugs are effective for their licensed indications. Your doctor will discuss which medication is the most suitable considering your health circumstances and condition which is being treated.

Notify your doctor immediately if you experience serious side effects while taking this medication, including very slow or irregular heartbeat, ankle or feet swelling, shortness of breath, sudden and unexplained weight gain, tingling in the fingers or toes, hair loss, changes in vision, eye pain, or mood changes such as nervousness.

To achieve weight loss, consider maintaining a food diary for two weeks, tracking your daily caloric intake. Reduce your average daily calorie intake by 250 calories. Additionally, engage in physical activities like walking, playing with children, walking the dog, playing basketball, or any activity that burns approximately 250 calories per day.

Beta-blockers may selectively promote the accumulation of abdominal fat, which is more sensitive to catecholamines than peripheral fat.

While using beta-blockers, it is advisable to avoid consuming products or beverages high in caffeine, such as coffee, soda, energy drinks, tea, and dark chocolate. Additionally, steer clear of over-the-counter cough and cold medicines, antihistamines, and antacids containing aluminum, and minimize alcohol consumption, as it may diminish the effectiveness of beta-blockers.

Weight gain is more likely to occur with older beta-blockers like atenolol and metoprolol. Newer beta-blockers such as carvedilol typically do not cause weight gain as a side effect.

Diuretics like hydrochlorothiazide may cause a temporary reduction in weight due to fluid loss. However, this effect does not impact long-term fat content.

Guidelines recommend the prescription of beta-blockers to all patients who have experienced a heart attack as part of a comprehensive risk reduction strategy. Typically, this treatment should be continued indefinitely.

Hair loss is a relatively rare side effect of various medications, including beta-blockers. Other drugs that may contribute to hair loss include blood thinners, antidepressants, cholesterol-lowering medications, certain nonsteroidal anti-inflammatory drugs (NSAIDs), and hormone-related drugs such as thyroid medications, hormone replacement therapies, or steroids.

Clinically apparent, acute liver injury attributable to bisoprolol is exceptionally rare, if it occurs at all. There have been no well-documented cases of such hepatotoxicity.

Coffee and other caffeine-containing beverages or foods, such as soda, high-energy drinks, tea, and dark chocolate, can counteract the antiadrenergic effects of beta-blockers, potentially reducing their efficacy.

Weight gain is a possible side effect of some beta-blockers, especially older ones like atenolol and metoprolol. On average, weight gain associated with beta-blockers is approximately 2.6 pounds (about 1.2 kilograms).

Serious side effects of bisoprolol may include chest pain, fast or irregular heartbeats, dizziness, blurred vision, shortness of breath, swelling of the ankles or feet, and rapid weight gain.

Seek medical attention if you experience sudden swelling of the lips, mouth, throat, or tongue, rapid or labored breathing, tightness in the throat, or difficulty swallowing.

Bisoprolol may potentially lead to heart failure in some patients. If you experience chest pain or discomfort, dilated neck veins, extreme fatigue, irregular breathing, an irregular heartbeat, shortness of breath, facial, finger, feet, or leg swelling, weight gain, or wheezing, consult your doctor immediately.

Hepatotoxicity associated with bisoprolol therapy is rare, with low rates of mild-to-moderate elevations in serum aminotransferase levels, typically asymptomatic and transient, and often resolving without discontinuing therapy.

Bisoprolol is prescribed for the prevention of future heart diseases, heart attacks, strokes, and the treatment of chest pain caused by angina. It is also used to manage conditions like atrial fibrillation and irregular heartbeats.

Zebeta (Bisoprolol) is an FDA-approved beta-blocker used to treat hypertension and congenital heart failure. Additionally, it is sometimes prescribed off-label to alleviate physical symptoms of anxiety, such as a racing heart, sweating, or trembling.

The two most common beta-blockers prescribed for anxiety are propranolol and atenolol. Other beta-blockers that may be suggested by your doctor include acebutolol, bisoprolol, carvedilol, and metoprolol. However, these are typically considered if propranolol or atenolol are not suitable.

Common side effects of beta-blockers include a slower heart rate, diarrhea, weakness, fatigue, dizziness, anxiety, changes in sex drive or performance, and nausea.

Typically, treatment with bisoprolol is long-term and may continue for the rest of your life. Consult your doctor before discontinuing the medication, as stopping it may lead to an increase in blood pressure, elevating the risk of heart attack and stroke.