Bisoprolol-hydrochlorothiazidePrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Bisoprolol-Hydrochlorothiazide
    Generic for Ziac
    30 tablets $10.8 USD
    Save $31.20
  3. Bisoprolol-Hydrochlorothiazide
    Generic for Ziac
    30 tablets $10.8 USD
    Save $31.20
  4. Bisoprolol-Hydrochlorothiazide
    Generic for Ziac
    30 tablets $10.8 USD
    Save $31.20
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Do you need a prescription for bisoprolol-hydrochlorothiazide?

Yes, bisoprolol-hydrochlorothiazide is only available with a valid physician Rx.

How much is bisoprolol-hydrochlorothiazide without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase bisoprolol-hydrochlorothiazide, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for bisoprolol-hydrochlorothiazide in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a bisoprolol-hydrochlorothiazide savings card?

Yes. Save up to 90% on your bisoprolol-hydrochlorothiazide with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a bisoprolol-hydrochlorothiazide coupon provider in the US?

No. Now Patient does not provide bisoprolol-hydrochlorothiazide coupons or FREE bisoprolol-hydrochlorothiazide samples.

Do you accept commercial, Medicare or Medicaid coverage for bisoprolol-hydrochlorothiazide in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much bisoprolol-hydrochlorothiazide?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using bisoprolol-hydrochlorothiazide. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much bisoprolol-hydrochlorothiazide. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic bisoprolol-hydrochlorothiazide?

Generic bisoprolol-hydrochlorothiazide refers to the non-brand-name version of the medication. It contains the same active ingredients as the brand-name drug but is typically less expensive.

FDA approval of bisoprolol-hydrochlorothiazide

Bisoprolol-hydrochlorothiazide is approved by the U.S. Food and Drug Administration (FDA) for the treatment of hypertension (high blood pressure).

Active ingredients of bisoprolol-hydrochlorothiazide

The active ingredients of bisoprolol-hydrochlorothiazide are bisoprolol fumarate and hydrochlorothiazide.

US brand name of bisoprolol-hydrochlorothiazide and manufacturer

Bisoprolol-hydrochlorothiazide is available in the US under various brand names, including Ziac. It is manufactured by various pharmaceutical companies.

UK brand name of bisoprolol-hydrochlorothiazide and manufacturer

In the UK, bisoprolol-hydrochlorothiazide combination is not available.

Prescription requirement for bisoprolol-hydrochlorothiazide

A prescription (Rx) is required for bisoprolol-hydrochlorothiazide in the US.

Availability of bisoprolol-hydrochlorothiazide in the UK with NHS Prescription

Bisoprolol-hydrochlorothiazide (hctz) is not available in the UK with an NHS prescription.

Conditions treated by bisoprolol-hydrochlorothiazide

Bisoprolol-hydrochlorothiazide is used for the treatment of hypertension (high blood pressure). It combines two medications with different mechanisms of action to help lower blood pressure effectively.

How does bisoprolol-hydrochlorothiazide work?

Bisoprolol belongs to a class of medications called beta blockers. It works by blocking the effects of certain chemicals in the body, such as adrenaline, which can increase heart rate and blood pressure. Hydrochlorothiazide is a thiazide diuretic that helps the kidneys remove excess salt and water from the body, reducing fluid volume and lowering blood pressure.

Forms of bisoprolol-hydrochlorothiazide available

Bisoprolol-hydrochlorothiazide is available in the form of oral tablets.

Dosage of bisoprolol-hydrochlorothiazide

The dosage of bisoprolol-hydrochlorothiazide may vary depending on the individual’s blood pressure levels and other factors. It is important to follow the prescribed dosage instructions provided by a healthcare professional.

Directions for bisoprolol-hydrochlorothiazide use

Bisoprolol-hydrochlorothiazide should be taken exactly as directed by the healthcare provider. The medication is usually taken once daily, with or without food. It is important to take bisoprolol-hydrochlorothiazide regularly to maintain blood pressure control.

Warnings and precautions for bisoprolol-hydrochlorothiazide

  • Bisoprolol-hydrochlorothiazide should be used with caution in individuals with certain medical conditions, such as heart failure or kidney problems. Dose adjustments may be necessary
  • Do not stop using this medication if you have chest pain (angina) or heart disease without speaking to your doctor first
  • It may interact with certain medications, including other blood pressure-lowering medications and nonsteroidal anti-inflammatory drugs (NSAIDs). Inform the healthcare provider about all medications being taken
  • Tell your doctor if you have kidney disease, liver disease, sinus bradycardia, heart failure, lung disease, an overactive thyroid, high calcium, or low potassium levels, any muscle diseases or skin cancer

Use of bisoprolol-hydrochlorothiazide during pregnancy

The use of bisoprolol-hydrochlorothiazide during pregnancy should be carefully considered, and the potential risks and benefits should be discussed with a healthcare provider.

Use of bisoprolol-hydrochlorothiazide while breastfeeding

Bisoprolol-hydrochlorothiazide should not be used while breastfeeding. It is important to discuss alternative options with a healthcare provider if breastfeeding is desired.

Possible side effects of bisoprolol-hydrochlorothiazide

Common side effects of bisoprolol-hydrochlorothiazide may include dizziness, tiredness, constipation, dry mouth, low blood pressure, increased urination, and electrolyte imbalances. Serious side effects are rare but can include shortness of breath, rapid weight gain, slow heart rate (bradycardia), and eye pain. Promptly report any adverse effects to a healthcare provider. Get medical help immediately if you have an allergic reaction. Symptoms may include hives, trouble breathing, swelling of your face, lips, tongue, or throat.

Interactions with other drugs

Bisoprolol may interact with other medications, including calcium channel blockers such as diltiazem and verapamil, clonidine, other beta blockers, diuretics, colestipol or cholestyramine, lithium, digoxin, and NSAIDs (such as ibuprofen and naproxen). It is important to inform your healthcare provider about all the prescription drugs, over the counter medication, supplements, and vitamins you are taking to avoid potential drug interactions.

Similar drugs to bisoprolol-hydrochlorothiazide

Other medications used for the treatment of hypertension include other beta blockers and thiazide diuretics.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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