Key facts about Zevtera
What is Zevtera?
Zevtera (ceftobiprole medocaril sodium) is an IV infusion used to treat certain bacterial infections.
What dosages is Zevtera available in?
Zevtera is available as a 667 mg (equivalent to 500 mg of ceftobiprole) single-dose vial.
What is Zevtera used for?
Zevtera is a cephalosporin antibacterial indicated for the treatment of: Adult patients with Staphylococcus aureus bloodstream infections (bacteremia) (SAB), including those with right-sided infective endocarditis Adult patients with acute bacterial skin and skin structure infections (ABSSSI) Adult and pediatric patients (3 months to less than 18 years old) with community-acquired bacterial pneumonia (CABP)
How does Zevtera work?
Zevtera kills bacteria and works by preventing the formation of the bacterial cell wall.
How do I take Zevtera?
Zevtera is given as an IV infusion every 6 to 8 hours by a healthcare provider.
Is it safe for me to take Zevtera?
Zevtera is a safe and effective treatment when used for FDA approved indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not take this medication if you have a severe hypersensitivity to Zevtera, or to other members of the cephalosporin class.
Zevtera Common Side Effects
Common side effects of Zevtera: Anemia Nausea Low potassium levels Vomiting Increased liver enzymes and bilirubin, Diarrhea, High blood pressure Leukopenia, Fever
Zevtera Serious Side Effects
Serious side effects are rare with Zevtera. Contact your healthcare provider immediately if you experience any of the following: Seizures and other adverse central nervous system (CNS) reactions Clostridioides difficile-associated diarrhea (CDAD)
Effects of other drugs, drug classes and over-the-counter products on Zevtera
The following medications may interact with Zevtera: Organic Anion Transporting Polypeptide 1B1/1B3 (OATP1B1/OATP1B3) Substrates: Zevtera may increase the plasma concentrations of OATP1B1 and OATP1B3 substrates. Concomitant administration is not recommended.
Who makes Zevtera?
Basilea Pharmaceutica Ltd.
Is Zevtera safe in pregnancy?
It is not known whether Zevtera will harm your unborn baby. Talk with your healthcare provider about the risks of taking this medication if you are pregnant or plan on becoming pregnant.
