Trihexyphenidyl Generic

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  1. Medication
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  2. Trihexyphenidyl HCl
    Generic for Artane
    30 tablets $4.5 USD
    Save $3.30
  3. Trihexyphenidyl HCl
    Generic for Artane
    30 tablets $5.4 USD
    Save $2.40
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Do you need a prescription for trihexyphenidyl?

Yes, trihexyphenidyl is only available with a valid physician Rx.

How much is trihexyphenidyl without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase trihexyphenidyl, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for trihexyphenidyl in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a trihexyphenidyl savings card?

Yes. Save up to 90% on your trihexyphenidyl with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a trihexyphenidyl coupon provider in the US?

No. Now Patient does not provide trihexyphenidyl coupons or FREE trihexyphenidyl samples.

Do you accept commercial, Medicare or Medicaid coverage for trihexyphenidyl in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much trihexyphenidyl?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using trihexyphenidyl. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much trihexyphenidyl. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic trihexyphenidyl?

Generic trihexyphenidyl refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of trihexyphenidyl

Trihexyphenidyl is approved by the U.S. Food and Drug Administration (FDA) for the treatment of parkinsonism and drug-induced extrapyramidal disorders.

Active ingredient of trihexyphenidyl

The active ingredient of trihexyphenidyl is trihexyphenidyl hydrochloride (trihexyphenidyl hcl).

US brand name of trihexyphenidyl and manufacturer

Trihexyphenidyl is available in the US under the brand name Artane. It is manufactured by Concordia Pharmaceuticals Inc.

UK brand name of trihexyphenidyl and manufacturer

In the UK, trihexyphenidyl is available under various brand names, including Artane and Benzhexol. The manufacturer may vary depending on the brand name.

Prescription requirement for trihexyphenidyl

A prescription (Rx) is required for trihexyphenidyl in both the US and the UK.

Availability of trihexyphenidyl in the UK with NHS prescription

Trihexyphenidyl is available in the UK with an NHS prescription.

Conditions treated by trihexyphenidyl

Trihexyphenidyl is an antimuscarinic, used alone or in combination with other drugs (levodopa) for the treatment of Parkinson’s disease, a group of movement disorders characterized by extrapyramidal symptoms such as tremors, difficulties with muscle control, and impaired balance and coordination. It can also be used to manage drug-induced extrapyramidal disorders caused by certain medications affecting the central nervous system (CNS).

How does trihexyphenidyl work?

Trihexyphenidyl is an anticholinergic agent. It works by blocking the action of a neurotransmitter called acetylcholine in the brain, which helps to reduce the abnormal muscle movements and other symptoms associated with parkinsonism and drug-induced extrapyramidal disorders.

Forms of trihexyphenidyl available

Trihexyphenidyl is available in the form of oral tablets and oral elixir.

Dosage of trihexyphenidyl

The dosage of trihexyphenidyl may vary depending on the individual’s condition, medical history, and response to the medication. It is important to follow the drug information provided by the healthcare provider.

Directions for trihexyphenidyl use

Trihexyphenidyl should be taken exactly as directed by the healthcare provider. The medication is usually taken orally, with or without food. It is important to swallow the tablets or solution whole and avoid crushing or chewing them.

Warnings and contraindications for trihexyphenidyl

  • Trihexyphenidyl may cause certain side effects, including dry mouth, blurred vision, constipation, and urinary retention. It may also have interactions with other medications. Inform the healthcare provider about all medications being taken
  • Tell your doctor if you have glaucoma, high blood pressure, stomach problems, heart disease, kidney disease, or liver disease
  • Use caution when driving or operating machinery, as trihexyphenidyl may cause drowsiness or dizziness

Use of trihexyphenidyl during pregnancy and breastfeeding

The use of trihexyphenidyl during pregnancy and breastfeeding should be carefully considered, and the potential risks and benefits should be discussed with a healthcare provider. trihexyphenidyl should only be used if the potential benefits outweigh the potential risks.

Possible side effects of trihexyphenidyl

In clinical trials common side effects of trihexyphenidyl may include dry mouth, blurred vision, narrow angle glaucoma, constipation, dizziness, and confusion. Serious side effects such as irregular heartbeats and mood changes are possible but less common. Promptly report any concerning symptoms to a healthcare provider. Get medical help right away if you have a serious side effect such as an allergic reaction. Symptoms include hives, trouble breathing, worsening shortness of breath, sore throat, chest pain, swelling of the face, tongue or throat, skin rash, blisters, and serious skin reactions.

Interactions with other drugs

Trihexyphenidyl may interact with other medications. It is important to inform your healthcare provider about all the prescription drugs, over the counter nonprescription medications, salt substitutes, herbal products, supplements, and vitamins you are taking to avoid potential adverse effects and drug interactions.

Similar drugs to trihexyphenidyl

Other anticholinergic medications used for the treatment of parkinsonism and drug-induced extrapyramidal disorders include benztropine and biperiden.


  • FDA Prescribing Information for Trihexyphenidyl
  • MHRA product information for Trihexyphenidyl
  • WebMD – Trihexyphenidyl
  • Drugs.com – Trihexyphenidyl
  • NHS UK
Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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