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Artane is the brand name for trihexyphenidyl and is available as an oral tablet.

Artane is available as a 2 mg and 5 mg oral tablet.

Artane is an anticholinergic medication that is used to treat Parkinson’s disease (PD) as well as movement problems (extrapyramidal symptoms or EPS) caused by central nervous system medications.

Artane is an anticholinergic medication. It works by blocking acetylcholine, a chemical that affects different functions in the body, including movement. In doing so, trihexyphenidyl relaxes your muscles to prevent muscle spasms and tremors.

Artane is typically started at a low dose and gradually increased. The usual dose is 5 mg to 15 mg by mouth per day. The dose can be split up into 3 doses and taken with meals.

Artane is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have angle-closure glaucoma.

Common side effects of Artane include:

• Dry mouth
• Blurry vision
• Dizziness
• Nausea
• Nervousness

Serious side effects are rare with Artane. Contact your healthcare provider immediately if you experience any of the following.

• Neuroleptic malignant syndrome: stiff muscles, sweating, fever, fast heartbeat, irregular pulse

The following medications may interact with Artane:

• Cannabinoids, barbituates, opiates, and alcohol – May have additive effects with Artane,and thus, an abuse potential exists
• Concurent use of alcohol or other CNS depressants – May cause increased sedative effects
• Monoamine oxidase inhibitors and trcyclic antidepressants – May intensify the anticholinergic effects

Wyeth Pharmaceuticals

It is not known if Artane will harm your unborn baby. If you become pregnant while receiving Artane, talk to your healthcare provider.

• Trihexyphenidyl