Triamterene-HCTZ Generic

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  1. Medication
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  2. Triamterene-HCTZ
    Generic for Maxzide
    30 tablets $5.1 USD
    Save $6.60
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Do you need a prescription for triamterene-hctz?

Yes, triamterene-hctz is only available with a valid physician Rx.

How much is triamterene-hctz without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase triamterene-hctz, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for triamterene-hctz in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a triamterene-hctz savings card?

Yes. Save up to 90% on your triamterene-hctz with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a triamterene-hctz coupon provider in the US?

No. Now Patient does not provide triamterene-hctz coupons or FREE triamterene-hctz samples.

Do you accept commercial, Medicare or Medicaid coverage for triamterene-hctz in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much triamterene-hctz?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using triamterene-hctz. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much triamterene-hctz. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic triamterene-HCTZ (triamterene and hydrochlorothiazide)?

US brand name of triamterene-HCTZ and manufacturer

Triamterene-HCTZ is available in the US under various brand names, including Dyazide, Maxzide, and others. These brands are manufactured by different pharmaceutical companies.

UK brand name of triamterene-HCTZ and manufacturer

Triamterene-HCTZ is not available as a combination brand name in the UK. However, it may be prescribed as a combination of individual components, triamterene and hydrochlorothiazide.

Prescription requirement for triamterene-HCTZ

Triamterene-HCTZ is a prescription medication in the US. It is not available over the counter and requires a prescription from a healthcare provider.

FDA approval of triamterene-HCTZ

Triamterene-HCTZ has received FDA approval for the treatment of edema (fluid retention) associated with various conditions, such as congestive heart failure, liver disease, and kidney disorders.

Is triamterene-HCTZ available in the UK on NHS?

Triamterene-HCTZ is not available on the NHS in the UK as a combination medication.  However, it can be prescribed as individual components (triamterene and hydrochlorothiazide). The availability and specific prescribing guidelines may vary, so it is recommended to consult with a healthcare provider or pharmacist for more information.

Mechanism of action

Triamterene-HCTZ is a combination medication that contains two active ingredients: triamterene and hydrochlorothiazide. Triamterene is a potassium-sparing diuretic that helps the kidneys eliminate excess salt and water from the body while retaining potassium. Hydrochlorothiazide is a thiazide diuretic that increases the excretion of salt and water from the kidneys. Together, they work to reduce fluid retention and lower blood pressure.

Uses of triamterene-HCTZ

Triamterene-HCTZ is primarily used to treat edema (fluid retention) associated with various conditions, including congestive heart failure, liver disease, and kidney disorders. It may also be used to manage high blood pressure (hypertension) when other medications alone are not sufficient.

Dosage of triamterene-HCTZ

The dosage of triamterene-HCTZ will depend on the individual’s condition and response to treatment. It is important to follow the dosage instructions provided by your healthcare provider. The medication is usually taken orally, once or twice daily.

Precautions and warnings for triamterene-HCTZ

  • Triamterene-HCTZ should not be used in individuals who are allergic to triamterene, hydrochlorothiazide, or any other components of the medication
  • Inform your healthcare provider about any known allergies or sensitivities to medications
  • Triamterene-HCTZ may interact with certain medications, including other diuretics, lithium, nonsteroidal anti-inflammatory drugs (NSAIDs), and certain blood pressure medications. It is important to inform your healthcare provider about all the medications you are taking
  • It is important to stay adequately hydrated and maintain appropriate electrolyte balance while taking triamterene-HCTZ. Your healthcare provider may monitor your blood pressure, kidney function, and electrolyte levels during treatment
  • Tell your doctor if you have diabetes, kidney stones, heart disease, kidney disease, or liver disease
  • Triamterene-HCTZ may pass into breast milk. Speak to your doctor before breast-feeding

Side effects of triamterene-HCTZ

Common side effects of triamterene-HCTZ may include dry mouth, dizziness, lightheadedness, drowsiness, headache, nausea, vomiting, muscle weakness, high potassium levels (hyperkalemia), and increased urination. If these side effects persist or worsen, it is important to contact a healthcare professional. Get medical help right away if you have a serious side effect such as an allergic reaction. Symptoms include hives, trouble breathing, worsening shortness of breath, sore throat, chest pain, swelling of the face, tongue or throat, skin rash, blisters, and serious skin reactions.

Interactions with other drugs

Triamterene-HCTZ may interact with other medications, including angiotensin-converting enzyme (ACE) inhibitors such lisinopril, digoxin, lithium, other medications that increase potassium levels (such as spironolactone, amiloride, or cyclosporine), medications for diabetes or high blood pressure, corticosteroids such as betamethasone, and nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen and naproxen. It is important to inform your healthcare provider about all the prescription drugs, over the counter nonprescription medications, salt substitutes, herbal products, potassium supplements, and vitamins you are taking to avoid potential adverse effects and drug interactions.

Similar drugs to triamterene-HCTZ

Other potassium-sparing diuretics, such as amiloride, may be used as alternatives to triamterene-HCTZ for the treatment of hypertension and edema.


  • U.S. Food and Drug Administration (FDA)
  • NHS
  • WebMD
  • MedlinePlus
Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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