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Sporanox is the brand name for itraconazole and is available as an oral capsule.

Sporanox is available as a 100 mg oral capsule and a 10 mg/ml oral solution.

Sporanox is an antifungal and is used to treat oral fungal infections (thrush) of the mouth and throat.

Sporanox is an antifungal solution. It kills the fungus causing the infection by damaging its protective outer layer.

Sporanox is dosed as follows:

• Oral thrush of the mouth: The typical dose is 200 mg by mouth without food once a day for 1 to 2 weeks
• Oral thrush of the mouth when fluconazole has already been tried: The typical dose is 100 mg by mouth without food twice a day for 2 to 4 weeks
• Oral thrush of the esophagus: The typical dose is 100 mg without food once a day for at least 3 weeks and until you’ve been symptom-free for 2 weeks in a row. Some people might need to take 200 mg per day if the lower dose isn’t working

Sporanox is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if any of the following apply:

• Congestive heart failure
• Taking medications that can lead to QT prolongation (e.g. dofetilide (Tikosyn), quinidine, pimozide (Orap), cisapride, methadone (Methadose), disopyramide (Norpace), Multaq (dronedarone), and ranolazine (Ranexa))
• Taking dihydroergotamine or ergotamine.
  People with kidney or liver problems taking colchicine (Colcrys), fesoterodine (Toviaz), or solifenacin (Vesicare)

Common side effects of Sporanox:

• Nausea
• Diarrhea
• Vomiting
• Fever
• Rash

Serious side effects are rare with Sporanox. Contact your healthcare provider immediately if you experience any of the following.

• Congestive heart failure (CHF): trouble breathing, swelling in the arms and legs, sudden weight gain, tiredness, dizziness, lightheadedness, feeling your heart beat very fast
• Abnormal heart rhythm: dizziness, feeling faint, lightheaded, feeling your heart beating fast
• Liver failure: nausea, vomiting, unusual tiredness, yellowing of the skin or whites of the eyes (jaundice), dark-colored urine, pale-colored stools

The following medications may interact with Sporanox:

• Coadministration of a number of CYP3A4 substrates are contraindicated with Sporanox
• Some examples of drugs for which plasma concentrations increase are: methadone, disopyramide dofetilide, dronedarone, quinidine, isavuconazole, ergot alkaloids (such as dihydroergotamine ergometrine (ergonovine), ergotamine, methylergometrine (methylergonovine)), irinotecan lurasidone, oral midazolam, pimozide, triazolam, felodipine, nisoldipine, ivabradine, ranolazine eplerenone, cisapride, naloxegol, lomitapide, lovastatin, simvastatin, avanafil, ticagrelor finerenone, voclosporin

Janssen Pharmaceuticals

Sporanox can harm your unborn baby. Tell your healthcare
provider right away if you become pregnant while taking Sporanox. Females who are able to become
pregnant must use effective forms of birth control during treatment and for 2 months after stopping treatment with
Sporanox.

• Itraconazole